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Hongyan Chen
Life Science
Fudan University
Shanghai
Language: English, Chinese
Gene Editing
Cell Therapy
Genetic Diseases
Gene Transfer
Molecular Biotechnology
Detection Technology
Non-Invasive Prenatal Diagnosis
Preimplantation Genetic Diagnosis
Thalassemia
Hemophilia
Areas of Focus
- Genetic Disease Gene Editing and Cell Therapy
- Genetic Disease Gene Detection and Application
Work Experience
- 2004.7-2005.10 - Second Military Medical University and Shanghai Fuchun Zhongnan Biotechnology Co., Ltd. - Postdoctoral Researcher
- 2005.10-2008.2 - National Neuroscience Institute of Singapore - Postdoctoral Researcher
- 2008.3-2008.8 - Singapore General Hospital - Research Scientist
- 2008.12-present - Fudan University - Lecturer, Associate Professor
Academic Background & Achievements
- 1998.9-2001.7 Master's Degree in Biochemistry and Molecular Biology: Xiamen University
- 2001.9-2004.7 PhD in Genetics: Fudan University
- Singapore Millennium Foundation scholarship
Publications
- Two novel genetic variants in the STK38L and RAB27A genes are associated with glioma susceptibility, Chen Hongyan, Chen G, Li G, Zhang S, Chen H, Chen Y, Duggan D, Hu Z, Chen J, Zhao Y, Zhao Y, Huang H, Zheng SL, Trent JM, Yu L, Jiang D, Mo Z, Wang H, Mou Y, Jiang T, Mao Y, Xu J, Lu D, 2019
- Shuttling SLC2A4RG is regulated by 14-3-3θ to modulate cell survival via caspase-3 and caspase-6 in human glioma, Yun D, Wang H, Wang Y, Chen Y, Zhao Z, Ma J, Ji Y, Huang Q, Chen J, Chen Hogyan, Lu D, 2019
- TRIM21 overexpression promotes tumor progression by regulating cell proliferation, cell migration and cell senescence in human glioma, Zhao Z, Wang Y, Yun D, Huang Q, Meng D, Li Q, Zhang P, Wang C, Chen Hongyan, Lu D, 2020
- Analysis of high-resolution human leucocyte antigen allele polymorphism in 3788 Han Chinese patients with leukaemia, Liao Kuankai, Zheng Zhongzheng, Yang Lan, Wang Liping, Wang Ningjuan, Zhang Lirong, Pan Jie, Du Keming, Hu Ying, Du Jinwei, Chen Hongyan, 2018
- CRISPR/Cas9-mediated somatic and germline gene correction to restore hemostasis in hemophilia B mice, Huai C, Jia C, Sun R, Xu P, Min T, Wang Q, Zheng C, Chen Hongyan, Lu D, 2017
- High expression of N-myc (and STAT) interactor predicts poor prognosis and promotes tumor growth in human glioblastoma, Meng D, Chen Y, Yun D, Zhao Y, Wang J, Xu T, Li X, Wang Y, Yuan L, Sun R, Song X, Huai C, Hu L, Yang S, Min T, Chen J, Chen Hongyan, Lu D, 2015
- REV3L 30UTR 460 T4C polymorphism in microRNA target sites contributes to lung cancer susceptibility, S Zhang, Chen Hongyan, X Zhao, J Cao, J Tong, J Lu, W Wu, H Shen, Q Wei, D Lu, 2013
- Association of Sequence Variants on Chromosomes 20, 11, and 5 (20q13.33, 11q23.3, and 5p15.33) With Glioma Susceptibility in a Chinese Population, Chen Hongyan, Chen Y, Zhao Y, Fan W, Zhou K, Liu Y, Zhou L, Mao Y, Wei Q, Xu J, Lu D, 2011
Awards
- Singapore Millennium Foundation scholarship
