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陈霁云
Life Science
厦门大学
福建
Language: 英语, 中文
Rna解旋酶
基因表达
调控
结构生物学
分子生物学
生物物理学
蛋白质结构
基因组学
生物化学
细胞生物学
Areas of Focus
- RNA解旋酶介导的基因表达与调控的结构生物学研究
Work Experience
- 2017-2020 - 北京大学医学部 - 博士后
- 2020至今 - 厦门大学生命科学学院 - 助理教授
Academic Background & Achievements
- 2014 - 北京大学基础医学专业学士学位
- 2017 - 北京大学生物物理学专业博士学位
Publications
- NRDE2 negatively regulates exosome functions by inhibiting MTR4 recruitment and exosome interaction, Wang J, Chen J, Wu G, Zhang H, Du X, Chen S, Zhang L, Wang K, Wu X, Gao S, Zhang S, Kuai B, Zhao P, Chi B, Wang L, Li G, Wong CCL, Zhou Y, Li J, Yun C, Cheng H, 2019
- Structure and function of human Naa60 (NatF), a Golgi-localized bi-functional acetyltransferase, Chen JY, Liu L, Cao CL, Li MJ, Tan K, Yang X, Yun CH, 2016
- Active-State Structures of a Small Heat-Shock Protein Revealed a Molecular Switch for Chaperone Function, Liu L, Chen JY, Yang B, Wang FH, Wang YH, Yun CH, 2015
- Crystal structure of EGFR T790M/C797S/V948R in complex with EAI045, Zhao P, Yao MY, Zhu SJ, Chen JY, Yun CH, 2018
- FOXO1 inhibition potentiates endothelial angiogenic functions in diabetes via suppression of ROCK1/Drp1-mediated mitochondrial fission, Shi Y, Fan S, Wang D, Huyan T, Chen J, Chen J, Su J, Li X, Wang Z, Xie S, Yun C, Li X, Tie L, 2018
- Discovery and characterization of a novel potent type II native and mutant BCR-ABL inhibitor (CHMFL-074) for Chronic Myeloid Leukemia (CML), Liu F, Wang B, Wang Q, Qi Z, Chen C, Kong LL, Chen JY, Liu X, Wang A, Hu C, Wang W, Wang H, Wu F, Ruan Y, Qi S, Liu J, Zou F, Hu Z, Wang W, Wang L, Zhang S, Yun CH, Zhai Z, Liu J, Liu Q, 2016
- Crystal structure and function of an unusual dimeric Hsp20.1 provide insight into the thermal protection mechanism of small heat shock proteins, Liu L, Chen J, Yang B, Wang Y, 2015
- Oligomer-dependent and -independent chaperone activity of sHsps in different stressed conditions, Liu L, Chen J, Yang B, Wang Y, 2015
