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Wei Feng
wfeng@ibp.ac.cn
English, Chinese
Beijing
University of Chinese Academy of Sciences
Life Sciences
  • 2001-09--2005-11 PhD in Biochemistry: Hong Kong University of Science and Technology
  • 1997-09--2001-07 Bachelor's in Chemistry: Fudan University
  • 2009-08~Present - Institute of Biophysics, Chinese Academy of Sciences - Researcher
  • 2007-08~2009-08 - Department of Biochemistry, Hong Kong University of Science and Technology - Research Assistant Professor
  • 2005-11~2007-08 - Department of Biochemistry, Hong Kong University of Science and Technology - Postdoctoral Research Assistant
Regulation of intracellular material transport by molecular motors
Structure and function of protein complexes involved in vesicle transport and autophagosome formation
  • A Plant Flavonol and Genetic Suppressors Rescues a Pathogenic Mutation Associated with Kinesin in Neurons, Chai, Yongping, Li, Dong, Gong, Weibin, Ke, Jingyi, Tian, Dianzhe, Chen, Zhe, Guo, Angel, Guo, Zhengyang, Li, Wei, Feng, Wei, Ou, Guangshuo, 2024
  • The HEAT repeat protein HPO-27 is a lysosome fission factor, Li, Letao, Liu, Xilu, Yang, Shanshan, Li, Meijiao, Wu, Yanwei, Hu, Siqi, Wang, Wenjuan, Jiang, Amin, Zhang, Qianqian, Zhang, Junbing, Ma, Xiaoli, Hu, Junyan, Zhang, Qiaohong, Liu, Yubing, Li, Dong, Hu, Junjie, Yang, Chonglin, Feng, Wei, Wang, Xiaochen, 2024
  • A non-canonical target-binding site in Munc18-1 domain 3b for assembling the Mint1-Munc18-1-syntaxin-1 complex, Li, Wei, Xing, Ying, Wang, Yue, Xu, Tao, Song, Eli, Feng, Wei, 2023
  • Intertwined Wdr47-NTD dimer recognizes a basic-helical motif in Camsap proteins for proper central-pair microtubule formation, Ren, Jinqi, Li, Dong, Liu, Juyuan, Liu, Hao, Yan, Xiumin, Zhu, Xueliang, Feng, Wei, 2022
  • Characterization of a thermostable, protease-tolerant inhibitor of α-glycosidase from carrot: A potential oral additive for treatment of diabetes, Hao, Yang, Guo, Tao, Ren, Jinqi, Wang, Yaxin, Wang, Lei, Shi, Yawei, Feng, Wei, 2022
  • The architecture of kinesin-3 KLP-6 reveals a multilevel-lockdown mechanism for autoinhibition, Wang, Wenjuan, Ren, Jinqi, Song, Weiye, Zhang, Yong, Feng, Wei, 2022
  • Crystal Structure of the Core Module of the Yeast Paf1 Complex, Chen, Feilong, Liu, Beibei, Zeng, Jianwei, Guo, Lu, Ge, Xuan, Feng, Wei, Li, DeFeng, Zhou, Hao, Long, Jiafu, 2022
  • Motor domain-mediated autoinhibition dictates axonal transport by the kinesin UNC-104/KIF1A, Cong, Dezi, Ren, Jinqi, Zhou, Yurong, Wang, Shuang, Jingjing Liang, Ding, Mei, Feng, Wei, 2021
  • Metaxins are core components of mitochondrial transport adaptor complexes, Zhao, Yinsuo, Song, Eli, Wang, Wenjuan, Hsieh, ChungHan, Wang, Xinnan, Feng, Wei, Wang, Xiangming, Shen, Kang, 2021
  • Biochemical insights into Paf1 complex-induced stimulation of Rad6/Bre1-mediated H2B monoubiquitination, Chen, Feilong, Liu, Beibei, Guo, Lu, Ge, Xuan, Feng, Wei, Li, De-Feng, Zhou, Hao, Long, Jiafu, 2021
  • CASK modulates the assembly and function of the Mint1/Munc18-1 complex to regulate insulin secretion, Zhang, Zhe, Li, Wei, Yang, Guang, Lu, Xuefeng, Qi, Xin, Wang, Shuting, Cao, Can, Zhang, Peng, Ren, Jinqi, Zhao, Jiaxu, Zhang, Junyi, Hong, Sheng, Tan, Yan, Burchfield, James, Yu, Yang, Xu, Tao, Yao, Xuebiao, James, David, Feng, Wei, Chen, Zhengjun, 2020
  • Multi-site-mediated entwining of the linear WIR-motif around WIPI beta-propellers for autophagy, Ren, Jinqi, Liang, Ruobing, Wang, Wenjuan, Zhang, Dachuan, Yu, Li, Feng, Wei, 2020
  • Structural Conservation of the Two Phosphoinositide-Binding Sites in WIPI Proteins, Liang, Ruobing, Ren, Jinqi, Zhang, Yong, Feng, Wei, 2019
  • YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization, Xu, Yang, Ren, Jinqi, He, Xiaolong, Chen, Han, Wei, Taotao, Feng, Wei, 2019
  • Structural conservation of the autoinhibitory domain in SUN proteins, Xu, Yang, Li, Wei, Ke, Huimin, Feng, Wei, 2018
  • Structural Delineation of the Neck Linker of Kinesin-3 for Processive Movement, Ren, Jinqi, Zhang, Yong, Wang, Shuang, Huo, Lin, Lou, Jizhong, Feng, Wei, 2018
  • Coiled-coil 1-mediated fastening of the neck and motor domains for kinesin-3 autoinhibition, Ren, Jinqi, Wang, Shuang, Chen, Han, Wang, Wenjuan, Huo, Lin, Feng, Wei, 2018
  • BORC regulates the axonal transport of synaptic vesicle precursors by activating ARL-8, Niwa Shinsuke, Tao Li, Lu Sharon Y., Liew Gerald M., Feng Wei, Nachury Maxence V., Shen Kang, 2017
  • Structural Correlation of the Neck Coil with the Coiled-coil (CC1)-Forkhead-associated (FHA) Tandem for Active Kinesin-3 KIF13A, Ren, Jinqi, Huo, Lin, Wang, Wenjuan, Zhang, Yong, Li, Wei, Lou, Jizhong, Xu, Tao, Feng, Wei, 2016
  • HID-1 is required for homotypic fusion of immature secretory granules during maturation, Du, Wen, Zhou, Maoge, Zhao, Wei, Cheng, Dongwan, Wang, Lifen, Lu, Jingze, Song, Eli, Feng, Wei, Xue, Yanhong, Xu, Pingyong, Xu, Tao, 2016
  • Coiled-Coil Domains of SUN Proteins as Intrinsic Dynamic Regulators, Nie, Si, Ke, Huimin, Gao, Feng, Ren, Jinqi, Wang, Mingzhu, Huo, Lin, Gong, Weimin, Feng, Wei, 2016
  • Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism, Yi, Fengshuang, Kong, Ruirui, Ren, Jinqi, Zhu, Li, Lou, Jizhong, Wu, Jane Y, Feng, Wei, 2016
  • Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression, Kong, Ruirui, Yi, Fengshuang, Wen, Pushuai, Liu, Jianghong, Chen, Xiaoping, Ren, Jinqi, Li, Xiaofei, Shang, Yulong, Nie, Yongzhan, Wu, Kaichun, Fan, Daiming, Zhu, Li, Feng, Wei, Wu, Jane Y, 2015
  • Interdomain interface-mediated target recognition by the Scribble PDZ34 supramodule, Ren, Jinqi, Feng, Lei, Bai, Yujie, Pei, Haohong, Yuan, Zengqiang, Feng, Wei, 2015
  • Structural Insights into the Intrinsic Self-Assembly of Par-3 N-Terminal Domain, Zhang, Yan, Wang, Wenjuan, Chen, Jia, Zhang, Kai, Gao, Feng, Gao, Bingquan, Zhang, Shuai, Dong, Mingdong, Besenbacher, Flemming, Gong, Weimin, Zhang, Mingjie, Sun, Fei, Feng, Wei, 2013
  • Structural Insights into the Redox-Regulated Dynamic Conformations of Human Protein Disulfide Isomerase, Wang, Chao, Li, Wei, Ren, Jinqi, Fang, Jingqi, Ke, Huimin, Gong, Weimin, Feng, Wei, Wang, Chihchen, 2013
  • The Balance between Capture and Dissociation of Presynaptic Proteins Controls the Spatial Distribution of Synapses, Wu, Ye E, Huo, Lin, Maeder, Celine I, Feng, Wei, Shen, Kang, 2013
  • Membrane-induced Lever Arm Expansion Allows Myosin VI to Walk with Large and Variable Step Sizes, Cong Yu, Jizhong Lou, Jingjing Wu, Lifeng Pan, Wei Feng, Mingjie Zhang, 2012
  • The CC1-FHA tandem as a central hub for controlling the dimerization and activation of kinesin-3 KIF1A, Huo, Lin, Yue, Yang, Ren, Jinqi, Yu, Jiang, Liu, Junlin, Yu, Yong, Ye, Fei, Xu, Tao, Zhang, Mingjie, Feng, Wei, 2012
  • Human Protein-disulfide Isomerase Is a Redox-regulated Chaperone Activated by Oxidation of Domain a ', Wang, Chao, Yu, Jiang, Huo, Lin, Wang, Lei, Feng, Wei, Wang, Chihchen, 2012
  • Cdc42-dependent formation of the ZO-1/MRCK beta complex at the leading edge controls cell migration, Huo, Lin, Wen, Wenyu, Wang, Rui, Kam, Chuen, Xia, Jun, Feng, Wei, Zhang, Mingjie, 2011
  • Organization and Dynamics of PDZ Domain-Related Supramodules in the Postsynaptic Density, Feng, Wei, Zhang, Mingjie, 2009
  • Myosin VI undergoes cargo-mediated dimerization, Yu, Cong, Feng, Wei, Miyanoiri, Yohei, Wen, Wenyu, Zhao, Yanxiang, Zhang, Mingjie, 2009
  • The Par-3 NTD adopts a PB1-like structure required for Par-3 oligomerization and membrane localization, Feng, Wei, Wu, Hao, Chan, Ling-Nga, Zhang, Mingjie, 2007
  • PDZ domains of
Molecular Motors Intracellular Transport Vesicle Transport Autophagosome Formation Protein Complexes Cell Biology Biochemistry Structural Biology Regulation Function

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