Professor | Ke Ren Cheng | Asia Growth Partners

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Name	Ke Ren Cheng
Contact Information	keren.cheng@zju.edu.cn
Language ability	English, Chinese
Province	Zhejiang

Upload Avatar (500 x 500)

Name

Ke Ren Cheng

Contact Information

keren.cheng@zju.edu.cn

Language ability

English, Chinese

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Medical

University/Lab Affiliation and Title

Zhejiang University

Faculty

Medical

Areas of Focus	Primordial germ cells Spermatogonial stem cells Reconstitution of germ cell fate
Publications	Defining the Cellular Origin of Seminoma by Transcriptional and Epigenetic Mapping to the Normal Human Germline, Cheng, K.; Seita, Y.; Whelan, E. C.; Yokomizo, R.; Hwang, Y. S.; Rotolo, A.; Krantz, I. D.; Ginsberg, J. P.; Kolon, T. F.; Lal, P.; Luo, X.; Pierorazio, P. M.; Linn, R. L.; Ryeom, S.; Sasaki, K., 2024 Efficient Generation of Marmoset Primordial Germ Cell-like Cells Using Induced Pluripotent Stem Cells, Seita, Y.; Cheng, K.; McCarrey, J. R.; Yadu, N.; Cheeseman, I. H.; Bagwell, A.; Ross, C. N.; Santana Toro, I.; Yen, L.; Vargas, S.; Navara, C. S.; Hermann, B. P.; Sasaki, K., 2023 Profiling the Epigenetic Landscape of the Spermatogonial Stem Cell: Part 2—Computational Analysis of Epigenomics Data, Cheng, K.; McCarrey, J. R., 2023 Profiling the Epigenetic Landscape of the Spermatogonial Stem Cell—Part 1: Epigenomics Assays, Cheng, K.; McCarrey, J. R., 2023 Reconstitution of Human Adrenocortical Specification and Steroidogenesis Using Induced Pluripotent Stem Cells, Sakata, Y.; Cheng, K.; Mayama, M.; Seita, Y.; Detlefsen, A. J.; Mesaros, C. A.; Penning, T. M.; Shishikura, K.; Yang, W.; Auchus, R. J.; Strauss, J. F.; Sasaki, K., 2022 Histone Methyltransferase DOT1L Is Essential for Self-Renewal of Germline Stem Cells, Lin, H.; Cheng, K.; Kubota, H.; Lan, Y.; Riedel, S. S.; Kakiuchi, K.; Sasaki, K.; Bernt, K. M.; Bartolomei, M. S.; Luo, M.; Wang, P. J., 2022 The Developmental Origin and the Specification of the Adrenal Cortex in Humans and Cynomolgus Monkeys, Cheng, K.; Seita, Y.; Moriwaki, T.; Noshiro, K.; Sakata, Y.; Hwang, Y. S.; Torigoe, T.; Saitou, M.; Tsuchiya, H.; Iwatani, C.; Hosaka, M.; Ohkouchi, T.; Watari, H.; Umazume, T.; Sasaki, K., 2022 The Embryonic Ontogeny of the Gonadal Somatic Cells in Mice and Monkeys, Sasaki, K.; Oguchi, A.; Cheng, K.; Murakawa, Y.; Okamoto, I.; Ohta, H.; Yabuta, Y.; Iwatani, C.; Tsuchiya, H.; Yamamoto, T., 2021 Unique Epigenetic Programming Distinguishes Regenerative Spermatogonial Stem Cells in the Developing Mouse Testis, Cheng, K.; Chen, I.-C.; Cheng, C.-H. E.; Mutoji, K.; Hale, B. J.; Hermann, B. P.; Geyer, C. B.; Oatley, J. M.; McCarrey, J. R., 2020 The Mammalian Spermatogenesis Single-Cell Transcriptome, from Spermatogonial Stem Cells to Spermatids, Hermann, B. P.; Cheng, K.; Singh, A.; Roa-De La Cruz, L.; Mutoji, K. N.; Chen, I.-C.; Gildersleeve, H.; Lehle, J. D.; Mayo, M.; Westernströer, B.; Law, N. C.; Oatley, M. J.; Velte, E. K.; Niedenberger, B. A.; Fritze, D.; Silber, S.; Geyer, C. B.; Oatley, J. M.; McCarrey, J. R., 2018 Effect of Oocyte Vitrification on Deoxyribonucleic Acid Methylation of H19, Peg3, and Snrpn Differentially Methylated Regions in Mouse Blastocysts, Cheng, K.-R.; Fu, X.-W.; Zhang, R.-N.; Jia, G.-X.; Hou, Y.-P.; Zhu, S.-E., 2014

Areas of Focus

Primordial germ cells
Spermatogonial stem cells
Reconstitution of germ cell fate

Publications

Defining the Cellular Origin of Seminoma by Transcriptional and Epigenetic Mapping to the Normal Human Germline, Cheng, K.; Seita, Y.; Whelan, E. C.; Yokomizo, R.; Hwang, Y. S.; Rotolo, A.; Krantz, I. D.; Ginsberg, J. P.; Kolon, T. F.; Lal, P.; Luo, X.; Pierorazio, P. M.; Linn, R. L.; Ryeom, S.; Sasaki, K., 2024
Efficient Generation of Marmoset Primordial Germ Cell-like Cells Using Induced Pluripotent Stem Cells, Seita, Y.; Cheng, K.; McCarrey, J. R.; Yadu, N.; Cheeseman, I. H.; Bagwell, A.; Ross, C. N.; Santana Toro, I.; Yen, L.; Vargas, S.; Navara, C. S.; Hermann, B. P.; Sasaki, K., 2023
Profiling the Epigenetic Landscape of the Spermatogonial Stem Cell: Part 2—Computational Analysis of Epigenomics Data, Cheng, K.; McCarrey, J. R., 2023
Profiling the Epigenetic Landscape of the Spermatogonial Stem Cell—Part 1: Epigenomics Assays, Cheng, K.; McCarrey, J. R., 2023
Reconstitution of Human Adrenocortical Specification and Steroidogenesis Using Induced Pluripotent Stem Cells, Sakata, Y.; Cheng, K.; Mayama, M.; Seita, Y.; Detlefsen, A. J.; Mesaros, C. A.; Penning, T. M.; Shishikura, K.; Yang, W.; Auchus, R. J.; Strauss, J. F.; Sasaki, K., 2022
Histone Methyltransferase DOT1L Is Essential for Self-Renewal of Germline Stem Cells, Lin, H.; Cheng, K.; Kubota, H.; Lan, Y.; Riedel, S. S.; Kakiuchi, K.; Sasaki, K.; Bernt, K. M.; Bartolomei, M. S.; Luo, M.; Wang, P. J., 2022
The Developmental Origin and the Specification of the Adrenal Cortex in Humans and Cynomolgus Monkeys, Cheng, K.; Seita, Y.; Moriwaki, T.; Noshiro, K.; Sakata, Y.; Hwang, Y. S.; Torigoe, T.; Saitou, M.; Tsuchiya, H.; Iwatani, C.; Hosaka, M.; Ohkouchi, T.; Watari, H.; Umazume, T.; Sasaki, K., 2022
The Embryonic Ontogeny of the Gonadal Somatic Cells in Mice and Monkeys, Sasaki, K.; Oguchi, A.; Cheng, K.; Murakawa, Y.; Okamoto, I.; Ohta, H.; Yabuta, Y.; Iwatani, C.; Tsuchiya, H.; Yamamoto, T., 2021
Unique Epigenetic Programming Distinguishes Regenerative Spermatogonial Stem Cells in the Developing Mouse Testis, Cheng, K.; Chen, I.-C.; Cheng, C.-H. E.; Mutoji, K.; Hale, B. J.; Hermann, B. P.; Geyer, C. B.; Oatley, J. M.; McCarrey, J. R., 2020
The Mammalian Spermatogenesis Single-Cell Transcriptome, from Spermatogonial Stem Cells to Spermatids, Hermann, B. P.; Cheng, K.; Singh, A.; Roa-De La Cruz, L.; Mutoji, K. N.; Chen, I.-C.; Gildersleeve, H.; Lehle, J. D.; Mayo, M.; Westernströer, B.; Law, N. C.; Oatley, M. J.; Velte, E. K.; Niedenberger, B. A.; Fritze, D.; Silber, S.; Geyer, C. B.; Oatley, J. M.; McCarrey, J. R., 2018
Effect of Oocyte Vitrification on Deoxyribonucleic Acid Methylation of H19, Peg3, and Snrpn Differentially Methylated Regions in Mouse Blastocysts, Cheng, K.-R.; Fu, X.-W.; Zhang, R.-N.; Jia, G.-X.; Hou, Y.-P.; Zhu, S.-E., 2014

Germ Cells Stem Cells Reconstitution Primordial Spermatogonial Epigenetics Transcriptional Mapping Seminoma Pluripotent Stem Cells Adrenocortical Specification

Junfeng Ji - Zhejiang University

Xudong Fu - Zhejiang University

Nan Liu - Zhejiang University

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