Professor | Zhaoqing Ba | Asia Growth Partners

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Name	Zhaoqing Ba
Contact Information	bazhaoqing@nibs.ac.cn
Language ability	English, Chinese
Province	Beijing

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Name

Zhaoqing Ba

Contact Information

bazhaoqing@nibs.ac.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	National Institute of Biological Sciences，Beijing
Faculty	national institute of biological sciences，Beijing
Academic Background & Achievements	2013 - Ph.D. in Biochemistry and Molecular Biology: National Institute of Biological Science (NIBS), Beijing & Beijing Normal University, Beijing, China 2008 - B.S. in Biotechnology: Jiangnan University, Wuxi, Jiangsu, China
Work Experience	2021 - Present - National Institute of Biological Sciences, Beijing - Assistant Investigator 2019-2021 - Harvard Medical School/Boston Children’s Hospital, Boston, USA - Instructor/Research Associate 2014-2019 - Harvard Medical School/Boston Children’s Hospital, Boston, USA - Postdoctoral Research Fellow 2013-2014 - Tsinghua University, Beijing, China - Postdoctoral Research Fellow

University/Lab Affiliation and Title

National Institute of Biological Sciences，Beijing

Faculty

national institute of biological sciences，Beijing

Academic Background & Achievements

2013 - Ph.D. in Biochemistry and Molecular Biology: National Institute of Biological Science (NIBS), Beijing & Beijing Normal University, Beijing, China
2008 - B.S. in Biotechnology: Jiangnan University, Wuxi, Jiangsu, China

Work Experience

2021 - Present - National Institute of Biological Sciences, Beijing - Assistant Investigator
2019-2021 - Harvard Medical School/Boston Children’s Hospital, Boston, USA - Instructor/Research Associate
2014-2019 - Harvard Medical School/Boston Children’s Hospital, Boston, USA - Postdoctoral Research Fellow
2013-2014 - Tsinghua University, Beijing, China - Postdoctoral Research Fellow

Areas of Focus	B lymphocytes and adaptive immunity Antibody diversification and B cell function regulation
Publications	Contribution of the IGCR1 regulatory element and the 3'Igh CTCF-binding elements to regulation of Igh V(D)J recombination, Liang, Z., Zhao, L., Ye, A.Y., Lin, S.G., Zhang, Y., Guo, C., Dai, H.Q., Ba, Z., Alt, F.W., 2023 CTCF orchestrates long-range cohesin-driven V(D)J recombinational scanning, Ba, Z., Lou, J., Ye, A.Y., Dai, H.-Q., Dring, E.W., Lin, S.G., Jain, S., Kyritsis, N., Kieffer-Kwon, K.-R., Casellas, R., Alt, F.W., 2020 CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning, Jain, S., Ba, Z., Zhang, Y., Dai, H.-Q., Alt, F.W., 2018 Highly Sensitive and Unbiased Approach for Elucidating Antibody Repertoires, Lin, S.G., Ba, Z., Du, Z., Zhang, Y., Hu, J., Alt, F.W., 2016 A Rapid Embryonic Stem Cell-Based Mouse Model for B-cell Lymphomas Driven by Epstein-Barr Virus Protein LMP1, Ba, Z., Meng, F.-L., Gostissa, M., Huang, P.-Y., Ke, Q., Wang, Z., Dao, M.N., Fujiwara, Y., Rajewsky, K., Zhang, B., Alt, F.W., 2015 A Role for Small RNAs in DNA Double-Strand Break Repair, Wei, W., Ba, Z., Gao, M., Wu, Y., Ma, Y., Amiard, S., White, C.I., Rendtlew Danielsen, J.M., Yang, Y.-G., Qi, Y., 2012 Loop extrusion mediates physiological Igh locus contraction for RAG scanning, Dai, H.-Q., Hu, H., Lou, J., Ye, A.Y., Ba, Z., Zhang, X., Zhang, Y., Zhao, L., Yoon, H.S., Chapdelaine-Williams, A.M., Kyritsis, N., Chen, H., Johnson, K., Lin, S., Conte, A., Casellas, R., Lee, C.-S., Alt, F.W., 2021 BCR selection and affinity maturation in Peyer’s patch germinal centres, Chen, H., Zhang, Y., Ye, A.Y., Du, Z., Xu, M., Lee, C.-S., Hwang, J.K., Kyritsis, N., Ba, Z., Neuberg, D., Littman, D.R., Alt, F.W., 2020 Fundamental roles of chromatin loop extrusion in antibody class switching, Zhang, X., Zhang, Y., Ba, Z., Kyritsis, N., Casellas, R., Alt, F.W., 2019 The fundamental role of chromatin loop extrusion in physiological V(D)J recombination, Zhang, Y., Zhang, X., Ba, Z., Liang, Z., Dring, E.W., Hu, H., Lou, J., Kyritsis, N., Zurita, J., Shamim, M.S., Presser Aiden, A., Lieberman Aiden E., Alt, F.W., 2019 IDN2 Interacts with RPA and Facilitates DNA Double-Strand Break Repair by Homologous Recombination in Arabidopsis, Liu, M., Ba, Z., Costa-Nunes, P., Wei, W., Li, L., Kong, F., Li, Y., Chai, J., Pontes, O., Qi, Y., 2017 Ago2 Facilitates Rad51 Recruitment and DNA Double-Strand Break Repair by Homologous Recombination, Gao, M., Wei, W., Li, M.-M., Wu, Y.-S., Ba, Z., Jin, K.-X., Li, M.-M., Liao, Y.-Q., Adhikari, S., Chong, Z., 2014

Areas of Focus

B lymphocytes and adaptive immunity
Antibody diversification and B cell function regulation

Publications

Contribution of the IGCR1 regulatory element and the 3'Igh CTCF-binding elements to regulation of Igh V(D)J recombination, Liang, Z., Zhao, L., Ye, A.Y., Lin, S.G., Zhang, Y., Guo, C., Dai, H.Q., Ba, Z., Alt, F.W., 2023
CTCF orchestrates long-range cohesin-driven V(D)J recombinational scanning, Ba, Z., Lou, J., Ye, A.Y., Dai, H.-Q., Dring, E.W., Lin, S.G., Jain, S., Kyritsis, N., Kieffer-Kwon, K.-R., Casellas, R., Alt, F.W., 2020
CTCF-Binding Elements Mediate Accessibility of RAG Substrates During Chromatin Scanning, Jain, S., Ba, Z., Zhang, Y., Dai, H.-Q., Alt, F.W., 2018
Highly Sensitive and Unbiased Approach for Elucidating Antibody Repertoires, Lin, S.G., Ba, Z., Du, Z., Zhang, Y., Hu, J., Alt, F.W., 2016
A Rapid Embryonic Stem Cell-Based Mouse Model for B-cell Lymphomas Driven by Epstein-Barr Virus Protein LMP1, Ba, Z., Meng, F.-L., Gostissa, M., Huang, P.-Y., Ke, Q., Wang, Z., Dao, M.N., Fujiwara, Y., Rajewsky, K., Zhang, B., Alt, F.W., 2015
A Role for Small RNAs in DNA Double-Strand Break Repair, Wei, W., Ba, Z., Gao, M., Wu, Y., Ma, Y., Amiard, S., White, C.I., Rendtlew Danielsen, J.M., Yang, Y.-G., Qi, Y., 2012
Loop extrusion mediates physiological Igh locus contraction for RAG scanning, Dai, H.-Q., Hu, H., Lou, J., Ye, A.Y., Ba, Z., Zhang, X., Zhang, Y., Zhao, L., Yoon, H.S., Chapdelaine-Williams, A.M., Kyritsis, N., Chen, H., Johnson, K., Lin, S., Conte, A., Casellas, R., Lee, C.-S., Alt, F.W., 2021
BCR selection and affinity maturation in Peyer’s patch germinal centres, Chen, H., Zhang, Y., Ye, A.Y., Du, Z., Xu, M., Lee, C.-S., Hwang, J.K., Kyritsis, N., Ba, Z., Neuberg, D., Littman, D.R., Alt, F.W., 2020
Fundamental roles of chromatin loop extrusion in antibody class switching, Zhang, X., Zhang, Y., Ba, Z., Kyritsis, N., Casellas, R., Alt, F.W., 2019
The fundamental role of chromatin loop extrusion in physiological V(D)J recombination, Zhang, Y., Zhang, X., Ba, Z., Liang, Z., Dring, E.W., Hu, H., Lou, J., Kyritsis, N., Zurita, J., Shamim, M.S., Presser Aiden, A., Lieberman Aiden E., Alt, F.W., 2019
IDN2 Interacts with RPA and Facilitates DNA Double-Strand Break Repair by Homologous Recombination in Arabidopsis, Liu, M., Ba, Z., Costa-Nunes, P., Wei, W., Li, L., Kong, F., Li, Y., Chai, J., Pontes, O., Qi, Y., 2017
Ago2 Facilitates Rad51 Recruitment and DNA Double-Strand Break Repair by Homologous Recombination, Gao, M., Wei, W., Li, M.-M., Wu, Y.-S., Ba, Z., Jin, K.-X., Li, M.-M., Liao, Y.-Q., Adhikari, S., Chong, Z., 2014

B Lymphocytes Adaptive Immunity Antibody Diversification B Cell Function Immune Response Pathogen Defense Chronic Infection Autoimmunity Tumor Immunity Vaccine Development

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