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Akihiro Yamanaka
yamank(at)cibr.ac.cn
Japanese, English
Beijing
Chinese Institute for Brain Research, Beijing
Brain Science and Anthropology
  • 1994 - Bachelor of Pharmacy: Shizuoka Prefectural University, Japan
  • 1996 - Master of Pharmacology: Shizuoka Prefectural University, Japan
  • 2000 - Doctor of Pharmacology: University of Tsukuba, Japan
  • 2022-present - Beijing Institute of Brain Science and Brain-like Research - Senior Researcher
  • 2012-2022 - Nagoya University Institute of Environmental Medicine, Japan - Professor
  • 2008 - National Institute for Physiological Sciences, Japan - Associate Professor
  • 2006 - Yale University, USA - Visiting Researcher
  • 2002 - University of Tsukuba, Japan - Assistant Professor
  • 2000 - University of Tsukuba, Japan - Research Assistant
  • 2018-2020: Japan Science and Technology Agency CREST Researcher
  • 2009-2013: Japan Science and Technology Agency PRESTO Researcher
  • 2005: Best Teacher Award, University of Tsukuba
  • 2003: APSS Young Scientist Award
Neural regulation of instinctive behaviors such as sleep/wakefulness, feeding, drinking, and sexual behavior
  • Remote control of neural function by X-ray-induced scintillation., Matsubara T, Yanagida T, Kawaguchi N, Nakano T, Yoshimoto J, Sezaki M, Takikawa H, Tsunoda SP, Horigane S, Ueda S, Takemoto-Kimura S, Kandori H, Yamanaka A, *Yamashita T, 2021
  • The mammalian circadian pacemaker regulates wakefulness via CRF neurons in the paraventricular nucleus of the hypothalamus., Ono D, Mukai Y, Hung CJ, Chowdhury S, Sugiyama T, *Yamanaka A, 2020
  • Dual orexin and MCH neuron-ablated mice display severe sleep attacks and cataplexy., Hung CJ, Ono D, Kilduff TS, *Yamanaka A, 2020
  • REM sleep–active MCH neurons are involved in forgetting hippocampus-dependent memories., Izawa S, Chowdhury S, Miyazaki T, Mukai Y, Ono D, Inoue R, Ohmura Y, Mizoguchi H, Kimura K, Yoshioka M, Terao A, Kilduff TS, *Yamanaka A, 2019
  • Dissociating orexin-dependent and -independent functions of orexin neurons using novel Orexin-Flp knock-in mice., Chowdhury S, Hung CJ, Izawa S, Inutsuka A, Kawamura M, Kawashima T, Bito H, Imayoshi I, Abe M, Sakimura K, *Yamanaka A, 2019
  • GABA neurons in the ventral tegmental area regulate non-rapid eye movement sleep in mice., Chowdhury S, Matsubara T, Miyazaki T, Ono D, Fukatsu N, Abe M, Sakimura K, Sudo Y, *Yamanaka A, 2019
  • Top-down cortical input during NREM sleep consolidates perceptual memory., Miyamoto D, Hirai D, Fung CC, Inutsuka A, Odagawa M, Suzuki T, Boehringer R, Adaikkan C, Matsubara C, Matsuki N, Fukai T, McHugh TJ, Yamanaka A, *Murayama M, 2016
  • Concurrent and robust regulation of feeding behaviors and metabolism by orexin neurons., Inutsuka A, Inui A, Tabuchi S, Tsunematsu T, Lazarus M, *Yamanaka A, 2014
  • Conditional ablation of orexin/hypocretin neurons: A new mouse model for the study of narcolepsy and orexin system function., Tabuchi S, Tsunematsu T, Black SW, Tominaga M, Maruyama M, Takagi K, Minokoshi Y, Sakurai T, *Kilduff TS, *Yamanaka A, 2014
  • Optogenetic manipulation of activity and temporally-controlled cell-specific ablation reveal a role for MCH neurons in sleep/wake regulation., Tsunematsu T, Ueno T, Tabuchi S, Inutsuka A, Tanaka KF, Hasuwa H, Kilduff TS, Terao A, *Yamanaka A, 2014
  • Acute optogenetic silencing of orexin/hypocretin neurons induces slow wave sleep in mice., Tsunematsu T, Kilduff TS, Boyden ES, Takahashi S, Tominaga M, *Yamanaka A, 2011
  • Orexin Directly Excites Orexin Neurons through Orexin 2 Receptor., Yamanaka A, Tabuchi S, Tsunematsu T, Fukazawa Y, Tominaga M, 2010
  • Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor., Muraki Y, *Yamanaka A, Tsujino N, Kilduff TS, Goto K, Sakurai T, 2004
  • Hypothalamic orexin neurons regulate arousal according to energy balance in mice., Yamanaka A, Beuckmann CT, Willie JT, Hara J, Tsujino N, Mieda M, Tominaga M, Yagami K, Sugiyama F, Goto K, Yanagisawa M, *Sakurai T, 2003
Neuropeptides Hypothalamus Instinctive Behavior Sleep Wakefulness Feeding Drinking Sexual Behavior Molecular Biology Optogenetics

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