Professor | Shan-Hua Li | Asia Growth Partners

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Name	Shan-Hua Li
Contact Information	lish@xmu.edu.cn
Language ability	Chinese, English, Korean
Province	Fujian

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Name

Shan-Hua Li

Contact Information

lish@xmu.edu.cn

Language ability

Chinese, English, Korean

Province

Fujian

University/Lab Affiliation and Title	Xiamen University
Faculty	Medical
Academic Background & Achievements	1991-1996: Bachelor of Medicine, Yanbian University Medical College 1996-1999: Master of Medicine, Yanbian University Medical College 2006-2010: Doctor of Medicine, Seoul National University College of Medicine
Work Experience	1999-2011: Assistant, Assistant Professor, Yanbian University Medical College 2010-2011: Postdoctoral Researcher, Seoul National University College of Medicine 2011-present: Associate Professor, Xiamen University School of Medicine

University/Lab Affiliation and Title

Xiamen University

Faculty

Medical

Academic Background & Achievements

1991-1996: Bachelor of Medicine, Yanbian University Medical College
1996-1999: Master of Medicine, Yanbian University Medical College
2006-2010: Doctor of Medicine, Seoul National University College of Medicine

Work Experience

1999-2011: Assistant, Assistant Professor, Yanbian University Medical College
2010-2011: Postdoctoral Researcher, Seoul National University College of Medicine
2011-present: Associate Professor, Xiamen University School of Medicine

Areas of Focus	Human Anatomy and Histology Epigenetics of Hypoxic Stress
Publications	Structure-based design, structure-activity relationship analysis, and antitumor activity of diaryl ether derivatives., Yang SM, Huang ZN, Zhou ZS, Hou J, Zheng MY, Wang LJ, Jiang Y, Zhou XY, Chen QY, Li SH, Li FN., 2015 Evaluation of Novel N-(piperidine-4-yl)benzamide Derivatives as Potential Cell Cycle Inhibitors in HepG2 Cells., Hou J, Zhao W, Huang ZN, Yang SM, Wang LJ, Jiang Y, Zhou ZS, Zheng MY, Jiang JL, Li SH, Li FN., 2015 The functional and mechanistic relatedness of EZH2 and menin in hepatocellular carcinoma., Gao SB, Xu B, Ding LH, Zheng QL, Zhang L, Zheng QF, Li SH, Feng ZJ, Wei J, Yin ZY, Hua X, Jin GH., 2014 Menin promotes hepatocellular carcinogenesis and epigenetically up-regulates Yap1 transcription., Xu B, Li SH, Zheng R, Gao SB, Ding LH, Yin ZY, Lin X, Feng ZJ, Zhang S, Wang XM, Jin GH., 2013 Interplay between menin and K-Ras in regulating lung adenocarcinoma., Wu Y, Feng ZJ, Gao SB, Matkar S, Xu B, Duan HB, Lin X, Li SH, Hua X, Jin GH., 2012 PHF2 histone demethylase acts as a tumor suppressor in association with p53 in cancer., Lee KH, Park JW, Sung HS, Choi YJ, Kim WH, Lee HS, Chung HJ, Shin HW, Cho CH, Kim TY, Li SH, Youn HD, Kim SJ, Chun YS., 2015 Red ginseng and 20(S)-Rg3 control testosterone-induced prostate hyperplasia by deregulating androgen receptor signaling., Bae JS, Park HS, Park JW, Li SH, Chun YS., 2012 von Hippel-Lindau protein adjusts oxygen sensing of the FIH asparaginyl hydroxylase., Li SH, Chun YS, Lim JH, Huang LE, Park JW., 2011 Hypoxia-inducible factor α subunit stabilization by NEDD8 conjugation is reactive oxygen species-dependent., Ryu JH, Li SH, Park HS, Park JW, Lee B, Chun YS., 2011 Survivin mediates prostate cell protection by HIF-1alpha against zinc toxicity., Yun YJ, Li SH, Cho YS, Park JW, Chun YS., 2010 Vitamin C supplementation prevents testosterone-induced hyperplasia of rat prostate by down-regulating HIF-1alpha., Li SH, Ryu JH, Park SE, Cho YS, Park JW, Lee WJ, Chun YS., 2010 Inhibitor of nuclear factor-kappaB alpha derepresses hypoxia-inducible factor-1 during moderate hypoxia by sequestering factor inhibiting hypoxia-inducible factor from hypoxia-inducible factor 1alpha., Shin DH, Li SH, Yang SW, Lee BL, Lee MK, Park JW., 2009 A novel mode of action of YC-1 in HIF inhibition: stimulation of FIH-dependent p300 dissociation from HIF-1{alpha}., Li SH, Shin DH, Chun YS, Lee MK, Kim MS, Park JW., 2008 Cloning of miniature pig HIF-1alpha and its responses to immunosuppressive agents., Kim KE, Jung YJ, Li SH, Chun YS, Ahn C, Park JW., 2008 CITED2 mediates the paradoxical responses of HIF-1alpha to proteasome inhibition., Shin DH, Li SH, Chun YS, Huang LE, Kim MS, Park JW., 2008

Areas of Focus

Human Anatomy and Histology
Epigenetics of Hypoxic Stress

Publications

Structure-based design, structure-activity relationship analysis, and antitumor activity of diaryl ether derivatives., Yang SM, Huang ZN, Zhou ZS, Hou J, Zheng MY, Wang LJ, Jiang Y, Zhou XY, Chen QY, Li SH, Li FN., 2015
Evaluation of Novel N-(piperidine-4-yl)benzamide Derivatives as Potential Cell Cycle Inhibitors in HepG2 Cells., Hou J, Zhao W, Huang ZN, Yang SM, Wang LJ, Jiang Y, Zhou ZS, Zheng MY, Jiang JL, Li SH, Li FN., 2015
The functional and mechanistic relatedness of EZH2 and menin in hepatocellular carcinoma., Gao SB, Xu B, Ding LH, Zheng QL, Zhang L, Zheng QF, Li SH, Feng ZJ, Wei J, Yin ZY, Hua X, Jin GH., 2014
Menin promotes hepatocellular carcinogenesis and epigenetically up-regulates Yap1 transcription., Xu B, Li SH, Zheng R, Gao SB, Ding LH, Yin ZY, Lin X, Feng ZJ, Zhang S, Wang XM, Jin GH., 2013
Interplay between menin and K-Ras in regulating lung adenocarcinoma., Wu Y, Feng ZJ, Gao SB, Matkar S, Xu B, Duan HB, Lin X, Li SH, Hua X, Jin GH., 2012
PHF2 histone demethylase acts as a tumor suppressor in association with p53 in cancer., Lee KH, Park JW, Sung HS, Choi YJ, Kim WH, Lee HS, Chung HJ, Shin HW, Cho CH, Kim TY, Li SH, Youn HD, Kim SJ, Chun YS., 2015
Red ginseng and 20(S)-Rg3 control testosterone-induced prostate hyperplasia by deregulating androgen receptor signaling., Bae JS, Park HS, Park JW, Li SH, Chun YS., 2012
von Hippel-Lindau protein adjusts oxygen sensing of the FIH asparaginyl hydroxylase., Li SH, Chun YS, Lim JH, Huang LE, Park JW., 2011
Hypoxia-inducible factor α subunit stabilization by NEDD8 conjugation is reactive oxygen species-dependent., Ryu JH, Li SH, Park HS, Park JW, Lee B, Chun YS., 2011
Survivin mediates prostate cell protection by HIF-1alpha against zinc toxicity., Yun YJ, Li SH, Cho YS, Park JW, Chun YS., 2010
Vitamin C supplementation prevents testosterone-induced hyperplasia of rat prostate by down-regulating HIF-1alpha., Li SH, Ryu JH, Park SE, Cho YS, Park JW, Lee WJ, Chun YS., 2010
Inhibitor of nuclear factor-kappaB alpha derepresses hypoxia-inducible factor-1 during moderate hypoxia by sequestering factor inhibiting hypoxia-inducible factor from hypoxia-inducible factor 1alpha., Shin DH, Li SH, Yang SW, Lee BL, Lee MK, Park JW., 2009
A novel mode of action of YC-1 in HIF inhibition: stimulation of FIH-dependent p300 dissociation from HIF-1{alpha}., Li SH, Shin DH, Chun YS, Lee MK, Kim MS, Park JW., 2008
Cloning of miniature pig HIF-1alpha and its responses to immunosuppressive agents., Kim KE, Jung YJ, Li SH, Chun YS, Ahn C, Park JW., 2008
CITED2 mediates the paradoxical responses of HIF-1alpha to proteasome inhibition., Shin DH, Li SH, Chun YS, Huang LE, Kim MS, Park JW., 2008

Human Anatomy Histology Embryology Hypoxic Stress Epigenetics Hif Signaling Pathway Cell Cycle Regulation Cell Proliferation Tumorigenesis Molecular Biology

Hua Dong Jiang - Zhejiang University

Xiaotong Hu - Zhejiang University

Juze Yang - Zhejiang University

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