Professor | Ruifeng Fan | Asia Growth Partners

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Name	Ruifeng Fan
Contact Information	fanruifeng@sdau.edu.cn
Language ability	Chinese, English
Province	Shandong

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Name

Ruifeng Fan

Contact Information

fanruifeng@sdau.edu.cn

Language ability

Chinese, English

Province

Shandong

University/Lab Affiliation and Title	Shandong Agricultural University
Faculty	Animal Science and Veterinary Medicine
Academic Background & Achievements	2014-2017 PhD in Veterinary Medicine: Northeast Agricultural University 2011-2014 Master's in Clinical Veterinary Medicine: Shandong Agricultural University 2007-2011 Bachelor's in Veterinary Medicine: Shandong Agricultural University Published over 40 SCI-indexed papers Co-editor of 'Illustrated Diagnosis and Treatment of Chicken Diseases' Contributor to 'Differential Diagnosis and Treatment of Abnormal Symptoms in Dairy Cows' Co-translator of 'Atlas of Small Animal CT and MRI'
Work Experience	2017-present - Shandong Agricultural University - Associate Professor

University/Lab Affiliation and Title

Shandong Agricultural University

Faculty

Animal Science and Veterinary Medicine

Academic Background & Achievements

2014-2017 PhD in Veterinary Medicine: Northeast Agricultural University
2011-2014 Master's in Clinical Veterinary Medicine: Shandong Agricultural University
2007-2011 Bachelor's in Veterinary Medicine: Shandong Agricultural University
Published over 40 SCI-indexed papers
Co-editor of 'Illustrated Diagnosis and Treatment of Chicken Diseases'
Contributor to 'Differential Diagnosis and Treatment of Abnormal Symptoms in Dairy Cows'
Co-translator of 'Atlas of Small Animal CT and MRI'

Work Experience

2017-present - Shandong Agricultural University - Associate Professor

Areas of Focus	Research on the biological functions of selenium and selenoproteins Research on the toxicity mechanisms and detoxification mechanisms of heavy metals and organic toxins
Publications	Mercuric chloride induces sequential activation of ferroptosis and necroptosis in chicken embryo kidney cells by triggering ferritinophagy, Chu J. H., Li L. X., Gao P. C., Chen X. W., Wang Z. Y., Fan R. F., 2022 Protective mechanism of selenium on mercuric chloride-induced testis injury in chicken via p38 MAPK/ATF2/iNOS signaling pathway, Chen X. W., Chu J. H., Li L. X., Gao P. C., Wang Z. Y., Fan R. F., 2022 Selenium ameliorates mercuric chloride-induced brain damage through activating BDNF/TrKB/PI3K/AKT and inhibiting NF-κB signaling pathways, Li L. X., Chu J. H., Chen X. W., Gao P. C., Wang Z. Y., Liu C., Fan R. F., 2022 Antagonistic effect of selenium on mercuric chloride in the central immune organs of chickens: The role of microRNA-183/135b-FOXO1/TXNIP/NLRP3 inflammasome axis, Gao P. C., Chen X. W., Chu J. H., Li L. X., Wang Z. Y., Fan R. F., 2022 Selenium alleviates mercury chloride-induced liver injury by regulating mitochondrial dynamics to inhibit the crosstalk between energy metabolism disorder and NF-κB/NLRP3 inflammasome-mediated inflammation, Gao P. C., Chu J. H., Chen X. W., Li L. X., Fan R. F., 2021 Persistent activation of Nrf2 promotes a vicious cycle of oxidative stress and autophagy inhibition in cadmium-induced kidney injury, Fan R. F., Tang K. K., Wang Z. Y., Wang L., 2021 Aberrant Gene Expression of Selenoproteins in Chicken Spleen Lymphocytes Induced by Mercuric Chloride, Chu J. H., Yan Y. X., Chen X. W., Gao P. C., Li L. X., Fan R. F., 2022 Involvement of Nrf2 and mitochondrial apoptotic signaling in trehalose protection against cadmium-induced kidney injury, Fan R. F., Li Z. F., Zhang D., Wang Z. Y., 2020 Selenium relieves oxidative stress, inflammation, and apoptosis within spleen of chicken exposed to mercuric chloride, Fan R. F., Liu J. X., Yan Y. X., Wang L., Wang Z. Y., 2020 Response of selenoproteins gene expression profile to mercuric chloride exposure in chicken kidney, Chu J. H., Yan Y. X., Gao P. C., Chen X. W., Fan R. F., 2020 Trehalose alleviates cadmium-induced brain damage by ameliorating oxidative stress, autophagy inhibition, and apoptosis, Tang K. K., Liu X. Y., Wang Z. Y., Qu K. C., Fan R. F., 2019 Selenium alleviates cadmium-induced inflammation and meat quality degradation via antioxidant and anti-inflammation in chicken breast muscles, Tang K. K., Li H. Q., Qu K. C., Fan R. F., 2019 Trehalose suppresses cadmium-activated Nrf2 signaling pathway to protect against spleen injury, Qu K. C., Wang Z. Y., Tang K. K., Zhu Y. S., Fan R. F., 2019 Selenium Mitigates Cadmium-Induced Adverse Effects on Trace Elements and Amino Acids Profiles in Chicken Pectoral Muscles, Qu K. C., Li H. Q., Tang K. K., Wang Z. Y., Fan R. F., 2020 Gga-let-7f-3p promotes apoptosis in selenium deficiency-induced skeletal muscle by targeting selenoprotein K, Fan R. F., Cao C. Y., Chen M. H., Shi Q. X., Xu S. W., 2018 Gene Silencing of Selenoprotein K Induces Inflammatory Response and Activates Heat Shock Proteins Expression in Chicken Myoblasts, Fan R. F., Yao H. D., Cao C. Y., Zhao X., Khalid A., Zhao J. X., Zhang Z. W., Xu S. W., 2017 Gene expression of selenoproteins can be regulated by selenoprotein K silencing in chicken myoblasts, Fan R. F., Yao H. D., Zhao X., Cao C. Y., Yang T. S., Luan Y. L., Zhang Z. W., Xu S. W., 2016

Areas of Focus

Research on the biological functions of selenium and selenoproteins
Research on the toxicity mechanisms and detoxification mechanisms of heavy metals and organic toxins

Publications

Mercuric chloride induces sequential activation of ferroptosis and necroptosis in chicken embryo kidney cells by triggering ferritinophagy, Chu J. H., Li L. X., Gao P. C., Chen X. W., Wang Z. Y., Fan R. F., 2022
Protective mechanism of selenium on mercuric chloride-induced testis injury in chicken via p38 MAPK/ATF2/iNOS signaling pathway, Chen X. W., Chu J. H., Li L. X., Gao P. C., Wang Z. Y., Fan R. F., 2022
Selenium ameliorates mercuric chloride-induced brain damage through activating BDNF/TrKB/PI3K/AKT and inhibiting NF-κB signaling pathways, Li L. X., Chu J. H., Chen X. W., Gao P. C., Wang Z. Y., Liu C., Fan R. F., 2022
Antagonistic effect of selenium on mercuric chloride in the central immune organs of chickens: The role of microRNA-183/135b-FOXO1/TXNIP/NLRP3 inflammasome axis, Gao P. C., Chen X. W., Chu J. H., Li L. X., Wang Z. Y., Fan R. F., 2022
Selenium alleviates mercury chloride-induced liver injury by regulating mitochondrial dynamics to inhibit the crosstalk between energy metabolism disorder and NF-κB/NLRP3 inflammasome-mediated inflammation, Gao P. C., Chu J. H., Chen X. W., Li L. X., Fan R. F., 2021
Persistent activation of Nrf2 promotes a vicious cycle of oxidative stress and autophagy inhibition in cadmium-induced kidney injury, Fan R. F., Tang K. K., Wang Z. Y., Wang L., 2021
Aberrant Gene Expression of Selenoproteins in Chicken Spleen Lymphocytes Induced by Mercuric Chloride, Chu J. H., Yan Y. X., Chen X. W., Gao P. C., Li L. X., Fan R. F., 2022
Involvement of Nrf2 and mitochondrial apoptotic signaling in trehalose protection against cadmium-induced kidney injury, Fan R. F., Li Z. F., Zhang D., Wang Z. Y., 2020
Selenium relieves oxidative stress, inflammation, and apoptosis within spleen of chicken exposed to mercuric chloride, Fan R. F., Liu J. X., Yan Y. X., Wang L., Wang Z. Y., 2020
Response of selenoproteins gene expression profile to mercuric chloride exposure in chicken kidney, Chu J. H., Yan Y. X., Gao P. C., Chen X. W., Fan R. F., 2020
Trehalose alleviates cadmium-induced brain damage by ameliorating oxidative stress, autophagy inhibition, and apoptosis, Tang K. K., Liu X. Y., Wang Z. Y., Qu K. C., Fan R. F., 2019
Selenium alleviates cadmium-induced inflammation and meat quality degradation via antioxidant and anti-inflammation in chicken breast muscles, Tang K. K., Li H. Q., Qu K. C., Fan R. F., 2019
Trehalose suppresses cadmium-activated Nrf2 signaling pathway to protect against spleen injury, Qu K. C., Wang Z. Y., Tang K. K., Zhu Y. S., Fan R. F., 2019
Selenium Mitigates Cadmium-Induced Adverse Effects on Trace Elements and Amino Acids Profiles in Chicken Pectoral Muscles, Qu K. C., Li H. Q., Tang K. K., Wang Z. Y., Fan R. F., 2020
Gga-let-7f-3p promotes apoptosis in selenium deficiency-induced skeletal muscle by targeting selenoprotein K, Fan R. F., Cao C. Y., Chen M. H., Shi Q. X., Xu S. W., 2018
Gene Silencing of Selenoprotein K Induces Inflammatory Response and Activates Heat Shock Proteins Expression in Chicken Myoblasts, Fan R. F., Yao H. D., Cao C. Y., Zhao X., Khalid A., Zhao J. X., Zhang Z. W., Xu S. W., 2017
Gene expression of selenoproteins can be regulated by selenoprotein K silencing in chicken myoblasts, Fan R. F., Yao H. D., Zhao X., Cao C. Y., Yang T. S., Luan Y. L., Zhang Z. W., Xu S. W., 2016

Selenium Selenoproteins Biological Functions Heavy Metals Organic Toxins Toxicity Mechanisms Detoxification Research Veterinary Medicine Animal Health

Baoquan Li - Shandong Agricultural University

Xingxing Shi - Shandong Agricultural University

Yang Dubao - Shandong Agricultural University

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