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Hongxiang Sun
Animal Sciences
Zhejiang University
Zhejiang
Language: Chinese, English
Systems Biology
Traditional Chinese Medicine
Multi-Omics
Integration Analysis
Compound Compatibility
Classic Prescriptions
Veterinary Medicine
Syndromes
New Drug Development
Natural Medicine
Areas of Focus
- Research on the material basis of traditional Chinese medicine based on systems biology
- Research on the mechanism of action of traditional Chinese medicine based on multi-omics integration analysis
- Research on the theory of compound compatibility of classic prescriptions of traditional Chinese medicine
- Biological basis research of traditional Chinese veterinary medicine syndromes
- Research and development of new traditional Chinese veterinary drugs
Publications
- linc-AAM facilitates gene expression contributing to macrophage activation and adaptive immune responses, Xiangfeng Chen, Yanfei He, Yongliang Zhu, Jing Du, Hongxiang Sun, 2021
- Quick and improved immune responses to inactivated H9N2 avian influenza vaccine by purified active fraction of Albizia julibrissin saponins, Hongxiang Sun, Liyan Fei, Binnian Zhu, Minghua Shi, 2020
- Establishment of indirect competitive enzyme linked immunosorbent assay for the detection of platycodin D in Radix Platycodonis, Luo, Shuai; He, Yanfei; and Sun, Hongxiang, 2020
- The ethnopharmacology, phytochemistry, pharmacology and toxicology of genus Albizia: A review, Yanfei He, Qiaowen Wang, Yiping Ye, Zhaoying Liu, Hongxiang Sun, 2020
- A comparative study on the mechanisms of innate immune responses in mice induced by Alum and Actinidia eriantha polysaccharide, Jing Du, Xiangfeng Chen, Yiping Ye, Hongxiang Sun, 2020
- Mechanisms of mixed Th1/Th2 responses in mice induced by Albizia julibrissin saponin active fraction by in silico analysis, Jing Du, Junjie Jin, Juanjuan Wang, Hongxiang Sun, 2020
- Activation of RAW264.7 macrophages by active fraction of Albizia julibrissin saponin via Ca2+–ERK1/2–CREB–lncRNA pathways, Chenying Wang, Jing Du, Xiangfeng Chen, Yongliang Zhu, Hongxiang Sun, 2019
- Hepatoprotective effect of the ethanol extract of Illicium henryi against acute liver injury in mice induced by lipopolysaccharide, Md Sodrul Islam, Hui Yu, Lingyan Miao, Zhaoying Liu, Yanfei He, Hongxiang Sun, 2019
- Rapid annotation and structural characterization of saponins in the active fraction of Albizia julibrissin by high‐performance liquid chromatography coupled with quadrupole time of flight mass spectrometry based on accurate mass database, Yanfe He, Tiantian Ni, Zhaoying Liu, Yiping Ye, Hongxiang Sun, 2019
- Ethanol extract of Illicium henryi attenuates LPS-Induced acute kidney injury in mice via regulating inflammation and oxidative stress, Md Sodrul Islam, Lingyan Miao, Hui Yu, Ziyi Han, Hongxiang Sun, 2019
- Comprehensive analysis of lncRNA and mRNA expression profiles in macrophages activated by Actinidia eriantha polysaccharide, Xiangfeng Chen, Jing Du, Yongliang Zhu, Caiqiao Zhang, Hongxiang Sun, 2019
- The polysaccharide from the roots of Actinidia eriantha activates RAW264.7 macrophages via regulating microRNA expression, Xiangfeng Chen, Lijia Yuan, Jing Du, Caiqiao Zhang, Hongxiang Sun, 2019
- The potential role of tubeimosides in cancer prevention and treatment, Md Sodrul Islam, Chenying Wang, Jingyou Zheng, Narayan Paudyal, Yongliang Zhu, Hongxiang Sun, 2019
- Evaluation and characteristics of immunological adjuvant activity of purified fraction of Albizia julibrissin saponins, Binnian Zhu, Tianyu He, Xiangyun Gao, Minghua Shi, Hongxiang Sun, 2019
- Antiasthmatic effects of Sanglong Pingchuan Decoction through inducing a balanced Th1/Th2 immune response, Binnian Zhu, Jun Dong, Xiangyun Gao, Yanfei He, Hongxiang Sun, 2018
- Role of ginsenosides in reactive oxygen species-mediated anticancer therapy, Islam M. D Sodrul, Chenying Wang, Xiangfeng Chen, Hongxiang Sun, 2018
- Pathway analysis of global gene expression change in dendritic cells induced by the polysaccharide from the roots of Actinidia eriantha, Du Jing, Xiangfeng Chen, Chenying Wang, Hongxiang Sun, 2018
- Stephanthraniline A and cyclosporine A synergize to inhibit T cell response in vitro and in vivo, Fengyang Chen, Lifei Zhou, Xiaoyu Li, Shifang Xu, Lijuan Gao, Hongxiang Sun, Yiping Ye, 2017
- Stephanthraniline A suppressed CD4+ T cell-mediated immunological hepatitis through impairing PKCθ function, Fengyang Chen, Lifei Zhou, XiaoYu Li, Jiawen Zhao, Shifang Xu, Wenhai Huang, Lijuan Gao, Shujuan Hao, Yiping Ye, Hongxiang Sun, 2016
- Immunological adjuvant effect of the peptide fraction from the larvae of Musca domestica, Liqing Chen, Juan Zhang, Hongxiang Sun, 2015
- Activation of RAW264.7 macrophages by the polysaccharides from the roots of Actinidia eriantha and its molecular mechanisms, Hongxiang Sun, Juan Zhang, Fengyang Chen, Xiangfeng Chen, Zhihua Zhou, Hui Wang, 2015
- Adjuvant-active fraction from Albizzia julibrissin saponins improves immune responses by inducing cytokine and chemokine at the site of injection, Hongxiang Sun, Shuwang He, Minghua Shi, 2014
- Cytotoxic and apoptosis-inducing activity of triterpene glycosides from Holothuria scabra and Cucumaria frondosa against HepG2 cells, Juanjuan Wang, Hua Han, Xiangfeng Chen, Yanghua Yi, Hongxiang Sun, 2014
- Anti-tumor and immunomodulatory activity of peptide fraction from the larvae of Musca domestica, Hongxiang Sun, Liqing Chen, Juan Zhang, Fengyang Chen, 2014
- The inhibitory effect of 3β-hydroxy-12-oleanen-27-oic acid on growth and motility of human hepatoma HepG2 cells through JNK and Akt signaling pathway, Juanjuan Wang, Xiangfeng Chen, Zhihua Zhou, Jinhui Li, Hongxiang Sun, 2013
- Stephanthraniline A inhibits the proliferation and activation of T cells in vitro and in vivo, Fengyang Chen, Yang Ni, Yiping Ye, Hongxiang Sun, Xiaoyu Li, Shifang Xu, 2012
- Screening and appraisal for immunological adjuvant-active fractions from Platycodon grandiflorum total saponins, Ke Ouyang, Liqing Chen, Hongxiang Sun, Jing Du, Minghua Shi, 2012
- Structure-function relationship of the saponins from the roots of Platycodon grandiflorum for hemolytic and adjuvant activity, Hongxiang Sun, Liqing Chen, Ke Ouyang, Kuiwang Wang, Jiyong Zhou, 2011
- Comparison of immunosuppressive activity of Stephanoside E and its aglycone from Stephanotis mucronata in vitro, Fengyang Chen, Yang Ni, Yiping Ye, Hongxiang Sun, Xiaoyu Li, Shifang Xu, 2010
- Platycodin D improves the immunogenicity of Newcastle disease virus-based recombinant avian influenza vaccine in mice, Yong Xie, Hongxiang Sun, Dou Li, 2010
- Platycodin D2 improves specific cellular and humoral response to hepatitis B surface antigen in mice, Yong Xie, Shuwang He, Hongxiang Sun, Dou Li, 2010
- Immunosuppressive effect of ethanol extract of Artemisia annua on specific antibody and cellular responses of mice against ovalbumin, Yanxiang Zhang, Hongxiang Sun, 2009
- Chemical composition and antitumor activity of different polysaccharides from the roots of Actinidia eriantha, Haishun Xu, Li Yao, Hongxiang Sun, Yuanwen Wu, 2009
- Antitumor and immunomodulatory activity of polysaccharides from the roots of Actinidia eriantha, Haishun Xu, Yuanwen Wu, Shifang Xu, Hongxiang Sun, Fengyang Chen, Li Yao, 2009
- Immunomodulatory activity of 3β,6β-dihydroxyolean-12-en-27-oic acid in tumor-bearing mice, Wen Deng, Hongxiang Sun, Fengyang Chen, Minli Yao, 2009
- ISCOMs and ISCOMATRIX adjuvants, Hongxiang Sun, Yong Xie, Yiping Ye, 2009
- Stemucronatoside L, a pregnane glycoside from the roots of Stephanotis mucronata, inhibits Th1/Th2 immune responses in vitro, Fengyang Chen, Yiping Ye, Hongxiang Sun, Xiaoyu Li, Hong Shi, 2009
- Novel polysaccharide adjuvant from the roots of Actinidia eriantha with dual Th1 and Th2 potentiating activity, Hongxiang Sun, Hui Wang, Haishun Xu, Yang Ni, 2009
- Advances in saponin-based adjuvants, Hongxiang Sun, Yong Xie, Yiping Ye, 2009
- Astilbotriterpenic acid induces growth arrest and apoptosis in HeLa cells through mitochondria-related pathways and reactive oxygen species (ROS) production, Yibin Zhang, Yiping Ye, Xiaodan Wu, Hongxiang Sun, 2009
- Platycodin D
Awards
- Zhejiang Provincial Science and Technology Award Second Prize (2009): Preclinical experimental study of a new drug for the treatment of tumor diseases with Filipendula
- Zhejiang Provincial Science and Technology Award Third Prize (2009): Study on the anti-inflammatory and immunosuppressive substances of Cynanchum paniculatum
