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Shu Zhu
Animal Science
Zhejiang University
Zhejiang
Language: Chinese, English
Gut Microbiota
Metabolites
Innate Immunity
Enteric Viruses
Antiviral
Gut-Lung Axis
Gut-Liver Axis
Gut-Brain Axis
Severe Pancreatitis
Hematological Diseases
Areas of Focus
- Regulation of host innate immunity against enteric viruses by gut microbiota and their metabolites
- Mechanisms of gut microbiota regulating antiviral immunity in extra-intestinal tissues through gut-lung, gut-liver, and gut-brain axes
- Molecular mechanisms of gut microbiota metabolites regulating hematological diseases such as severe pancreatitis
Work Experience
- 2017.9-present - Zhejiang University, College of Animal Sciences - Researcher
- 2016.2-2017.7 - University of Florida, College of Medicine, Department of Molecular Genetics and Microbiology - Assistant Researcher
- 2011.2-2016.2 - University of Florida, College of Medicine, Department of Molecular Genetics and Microbiology - Postdoctoral Research Assistant
Academic Background & Achievements
- 2005.9-2010.6 Ph.D. in Preventive Veterinary Medicine: China Agricultural University (Supervisor: Professor Hanchun Yang)
- 2001.9-2005.6 Bachelor's in Veterinary Medicine: Huazhong Agricultural University
Publications
- Ginsenoside Rg3 enriches SCFA-producing commensal bacteria to confer protection against enteric viral infection via the cGAS-STING-type I IFN axis, Gan Wang, Jingtianyi Liu, Yanan Zhang, Jinyan Xie, Shuxian Chen, Yuhua Shi, Fushan Shi, Shu J. Zhu, 2023
- Akkermansia muciniphila protects mice against an emerging tick-borne viral pathogen, Jinyan Xie, Hao Li, Yiaoai Zhang, Tong Yang, Mengjia Yue, Junfa Zhang, Shuxian Chen, Ning Cui, Jingyun Li, Shu J. Zhu, Wei Liu, 2023
- Bifidobacterium spp. and their metabolite lactate protect against acute pancreatitis via inhibition of pancreatic and systemic inflammatory responses, Han Li, Jinyan Xie, Xiuliu Guo, Guilian Yang, Bin Cai, Jingtianyi Liu, Mengjia Yue, Yixin Tang, Gan Wang, Shuxian Chen, Jialin Guo, Xuchen Qi, Donghai Wang, Huijun Zheng, Wei Liu, Hong Yu, Chunfeng Wang, Shu J. Zhu, Feng Guo, 2022
- Bile acids promote the caveolae-associated entry of swine acute diarrhea syndrome coronavirus in porcine intestinal enteroids, Qiyue Yang, Yongle Yang, Yixin Tang, Pan Qin, Gan Wang, Jinyan Xie, Shuxian Chen, Chan Ding, Yaowei Huang, Shu J. Zhu, 2022
- The Intestinal Microbiome Primes Host Innate Immunity against Enteric Virus Systemic Infection through Type I Interferon, Xiaolian Yang, Gan Wang, Jinyan Xie, Han Li, Shuxian Chen, Wei Liu, Shu J. Zhu, 2021
- Broad cross-species infection of cultured cells by the bat HKU2-related swine acute diarrhea syndrome coronavirus (SADS-CoV) and identification of its replication in murine dendritic cells in vivo highlight its potential for diverse interspecies transmission, Yang YL, Qin P, Wang B, Liu Y, Xu GH, Peng L, Zhou J, Zhu SJ, Huang YW, 2019
