Upload Avatar (500 x 500)
Lenan Zhuang
Animal Science
Zhejiang University
Zhejiang
Language: Chinese, English
Comparative Biomedical
Animal Precision Medicine
Gene Editing
Genetic Diseases
Cell Models
Animal Models
Gene Therapy
Molecular Biology
Cardiovascular Diseases
Precision Treatment
Areas of Focus
- Comparative Biomedical and Animal Precision Medicine
- Epigenetics and Transcriptional Regulation Mechanisms in Cell Energy Metabolism and Related Diseases
Work Experience
- 2020-01 to 2022-12 - Principal Investigator: National Natural Science Foundation of China
- 2020-01 to 2021-12 - Principal Investigator: Zhejiang University
- 2020-12 to 2023-11 - Participant: National Key R&D Program
- 2021-12 to 2026-11 - Project Leader: National Key R&D Program
- 2023-01 to 2026-12 - Principal Investigator: National Natural Science Foundation of China
Academic Background & Achievements
- 2005 - Bachelor's Degree in Biology: Shaanxi Normal University
- 2011 - Ph.D. in Cell Biology: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
- 2013 - Research on Epigenetics and Metabolic Diseases: National Institutes of Health (NIH), USA
- 2018 - Research on Epigenetics and Muscle and Heart Diseases: University of Texas Southwestern Medical Center (UTSW), USA
Publications
- Transcriptomic Analyses and Experimental Validation Identified Immune-Related lncRNA–mRNA Pair MIR210HG–BPIFC Regulating the Progression of Hypertrophic Cardiomyopathy, Yuan Zhang, Jiuxiao Zhao, Qiao Jin, and Lenan Zhuang, 2024
- Barnacle-Inspired Wet Tissue Adhesive Hydrogels with Inherent Antibacterial Properties for Infected Wound Treatment, Zhenning Zhang, Zhipeng Ni, Yudi Huang, Hua Zhang, Zhewei Hu, Di Ye, Yihua Shen, Mengyan Jia, Kehang Shi, Ge Zhu, Jin He, Lichang Xu, Fushan Shi, Haojie Yu, Lenan Zhuang, and Huanan Wang, 2023
- Identification of JPX-RABEP1 Pair as an Immune-Related Biomarker and Therapeutic Target in Pulmonary Arterial Hypertension by Bioinformatics and Experimental Analyses, Qian Gong, Zhewei Hu, Qiao Jin, Yan Yan, Yan Liu, Jin He, Lenan Zhuang, and Huanan Wang, 2022
- Bioinformatics and Experimental Analyses Reveal Immune-Related LncRNA–mRNA Pair AC011483.1-CCR7 as a Biomarker and Therapeutic Target for Ischemic Cardiomyopathy, Qiao Jin, Qian Gong, Xuan Le, Jin He, and Lenan Zhuang, 2022
- Bioinformatics and Experimental Analyses Reveal NFIC as An Upstream Transcriptional Regulator for Ischemic Cardiomyopathy, Yang Ye, Qiao Jin, Qian Gong, Aoqi Li, Minghao Sun, Sibo Jiang, Yulan Jin, Zhe Zhang, Jin He, and Lenan Zhuang, 2022
- Multifunctional elastomer cardiac patches for preventing left ventricle remodeling after myocardial infarction in vivo, Yuejun Yao, Aoqi Li, Shuqin Wang, Yuwen Lu, Jieqi Xie, Haolan Zhang, Deteng Zhang, Jie Ding, Zhaoyi Wang, Chenxi Tu, Liyin Shen, Lenan Zhuang, Yang Zhu, and Changyou Gao, 2022
- Integrated Bioinformatics Analysis Reveals Marker Genes and Potential Therapeutic Targets for Pulmonary Arterial Hypertension, Aoqi Li, Jin He, Zhe Zhang, Sibo Jiang, Yun Gao, Yuchun Pan, Huanan Wang, and Lenan Zhuang, 2021
- Molecular Phylogenetic Analysis of the AIG Family in Vertebrates, Huang Yuqi, Sun Minghao, Lenan Zhuang, and He Jin, 2021
- Secreted MG53 from striated muscle impairs systemic insulin sensitivity, Lenan Zhuang, Rhonda Bassel-Duby, and Eric N. Olson, 2019
- Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function, Lenan Zhuang, Younghoon Jang, Young-Kwon Park, Ji-Eun Lee, Shalini Jain, Eugene Froimchuk, Aaron Broun, Chengyu Liu, Oksana Gavrilova, and Kai Ge, 2018
- βarrestin1 represses adipogenesis and inflammatary responses through its interaction with PPARγ, Lenan Zhuang, Wen-xiang Hu, Shun-mei Xin, Jian Zhao, and Gang Pei, 2011
- βarrestin1 represses diet-induced obesity, Lenan Zhuang, Wen-xiang Hu, Ming-liang Zhang, Shun-mei Xin, Wei-ping Jia, Jian Zhao, and Gang Pei, 2011
- Research progress of key molecules related with Alzheimer's disease, Lenan Zhuang, 2007
- Real time observation on cells in different fixed conditions and living cells in buffer solution by AFM, Lenan Zhuang, Hao Qi, Runguang Sun, Wenfang Chen, Ying Liu, and Jie Zhu, 2005
