1986-1990 Bachelor's Degree: Zhejiang University, Department of Chemical Engineering
1992-1997 Doctoral Degree: Zhejiang University, National Key Laboratory of Industrial Control Technology
2004 Promoted to Professor and Doctoral Supervisor
Director of the Institute of Pharmaceutical Informatics, Zhejiang University
Director of the Department of Traditional Chinese Medicine Science and Engineering, Zhejiang University
Director of the Key Laboratory of Traditional Chinese Medicine (TCM) Pharmaceutical Engineering, Zhejiang Province
Selected for the Ministry of Education's New Century Excellent Talents Support Program
Key support from Zhejiang Province's 'New Century 151 Talent Project'
2004.12-present - Zhejiang University, College of Pharmaceutical Sciences - Professor
2003.1-2004.11 - Zhejiang University, College of Pharmaceutical Sciences - Associate Professor
2001.1-2002.12 - Zhejiang University, College of Materials and Chemical Engineering - Associate Professor
1997.6-2000.12 - Zhejiang University, Department of Information and Electronic Engineering - Lecturer
1990.7-1992.8 - Baosteel Chemical Company, Shanghai - Assistant Engineer
National Science and Technology Progress Award First Prize (2014)
National Science and Technology Progress Award Second Prize (2004)
Provincial and Ministerial Science and Technology Award Special Prize
Provincial and Ministerial Science and Technology Award First Prize
Provincial and Ministerial Science and Technology Award Second Prize (7 times)
Provincial and Ministerial Science and Technology Award Third Prize (2 times)
8th Zhejiang Youth Science and Technology Award
Research
Pharmaceutical Process Analytical Technology (PAT) Quality by Design (QbD) in Pharmaceuticals Big Data Analysis in Pharmaceutical Industry
Combining Convolutional Neural Networks and In‐line Near‐infrared Spectroscopy for Real‐time Monitoring of the Chromatographic Elution Process in Commercial Production of Notoginseng Total Saponins, Yan, X., Fu, H., Zhang, S., & Qu, H., 2019
Development of an on‐line Raman spectral analytical method for monitoring and endpoint determination of the Cornu Caprae Hircus hydrolysis process, Yan, X., Li, W., Zhang, X., Liu, S., & Qu, H., 2019
Application of definitive screening design to quantify the effects of process parameters on key granule characteristics and optimize operating parameters in pulsed-spray fluid-bed granulation, Zhao, J., Li, W., Qu, H., Tian, G., & Wei, Y., 2019
Pharmacological and transcriptome profiling analyses of Fufang E'jiao Jiang during chemotherapy-induced myelosuppression in mice, Zhang, Y., Ye, T., Hong, Z., Gong, S., Zhou, X., Liu, H., ... & Qu, H., 2019
RNA-sequencing based bone marrow cell transcriptome analysis reveals the potential mechanisms of E'jiao against blood-deficiency in mice, Zhang, Y., Ye, T., Gong, S., Hong, Z., Zhou, X., Liu, H., ... & Qian, J., 2019
Chemometric identification of canonical metabolites linking critical process parameters to monoclonal antibody production during bioprocess development, Shen, L., Yan, X., Nie, L., Xu, W., Miao, S., Wang, H., ... & Qu, H., 2019
Rapid analysis of the Tanreqing injection by near-infrared spectroscopy combined with least squares support vector machine and Gaussian process modeling techniques, Li, W., Yan, X., Pan, J., Liu, S., Xue, D., & Qu, H., 2019
Development and validation of in-line near-infrared spectroscopy based analytical method for commercial production of a botanical drug product, Zhang, S., Xiong, H., Zhou, L., Ju, W., Yang, Z., Yan, K., ... & Qu, H., 2019
Development and Qualification of a Scale-Down Mammalian Cell Culture Model and Application in Design Space Development by Definitive Screening Design, Nie, L., Gao, D., Jiang, H., Gou, J., Li, L., Hu, F., ... & Qu, H., 2019
Preparation of Salvianolic Acid B Disodium Salt Considering the Water Extract Quality Standard, Ye, T., Qu, H., & Gong, X., 2019
Combining convolutional neural networks and on-line Raman spectroscopy for monitoring the Cornu Caprae Hircus hydrolysis process, Yan, X., Zhang, S., Fu, H., & Qu, H., 2019
Critical process parameter identification of manufacturing processes of Astragali Radix extract with a weighted determination coefficient method, Sun, M. F., Yang, J. Y., Cao, W., Shao, J. Y., Wang, G. X., Qu, H. B., ... & Gong, X. C., 2019
Application of near-infrared spectroscopy combined with design of experiments for process development of the pulsed spray fluid bed granulation process, Tian, G., Wei, Y., Zhao, J., Li, W., & Qu, H., 2018
In-situ monitoring of saccharides removal of alcohol precipitation using near-infrared spectroscopy, Huang, H., & Qu, H., 2018
In-line Vis-NIR spectral analysis for the column chromatographic processes of Ginkgo biloba part I: End-point determination of the elution process, Li, W., Yan, X., Chen, H., & Qu, H., 2018
Optimization of a Coupling Process for Insulin Degludec According to a Quality by Design (QbD) Paradigm, Nie, L., Hu, M., Yan, X., Guo, T., Wang, H., Zhang, S., & Qu, H., 2018
A novel quality by design approach for developing an HPLC method to analyze herbal extracts: A case study of sugar content analysis, Shao, J., Cao, W., Qu, H., Pan, J., & Gong, X., 2018
Modeling of degradation kinetics of Salvianolic acid B at different temperatures and pH values, Gong, X., Huang, S., Pan, J., & Qu, H., 2017
Rapid quantification of multi-components in alcohol precipitation liquid of Codonopsis Radix using near infrared spectroscopy (NIRS), Luo, Y., Li, W., Huang, W. H., Liu, X. H., Song, Y. G., & Qu, H. B., 2017
Measurement and Correlation of Liquid–Liquid Equilibria for the Ternary Systems of Water+ d-Fructose+ 1-Butanol, Water+ d-Glucose+ 1-Butanol, and Water+ d-Galactose+ 1-Butanol at (288.2, 303.2 and 318.2) K, Ye, T., Qu, H., & Gong, X., 2017
A feasibility research on the monitoring of traditional Chinese medicine production process using NIR-based multivariate process trajectories, Li, W., Han, H., Cheng, Z., Zhang, Y., Liu, S., & Qu, H., 2016
Chromatographic elution process design space development for the purification of saponins in Panax notoginseng extract using a probability‐based approach, Chen, T., Gong, X., Chen, H., Zhang, Y., & Qu, H., 2016
Development of an analytical method by defining a design space: a case study of saponin determination for Panax notoginseng extracts, Gong, X., Zhang, Y., Chen, H., Chen, T., Pan, J., Wang, X., & Qu, H., 2016
Determination of total organic carbon and soluble solids contents in Tanreqing injection intermediates with NIR spectroscopy and chemometrics, Li, W., & Qu, H., 2016
Identification of bioactive ingredients with immuno-enhancement and anti-oxidative effects from Fufang-Ejiao-Syrup by LC–MSn combined with bioassays, Shen, L., Chen, H., Zhu, Q., Wang, Y., Wang, S., Qian, J., ... & Qu, H., 2016
Monitoring of the hydrolysis process of bear bile powder using near infrared spectroscopy and chemometrics, Li, W., Cheng, Z., & Qu, H., 2016
The determination of dissociation constants for active ingredients from herbal extracts using a liquid–liquid equilibrium method, Gong, X., Huang, S., Jiao, R., Pan, J., Li, Y., & Qu, H., 2016
Degradation Kinetics and Mechanism of Lithospermic Acid under Low Oxygen Condition Using Quantitative 1H N
Keywords
Pharmaceutical Process Analytical Technology (Pat)Quality By Design (Qbd) In PharmaceuticalsBig Data Analysis In Pharmaceutical IndustryTraditional Chinese MedicinePharmaceutical InformaticsNear-Infrared SpectroscopyChemometricsBioprocess DevelopmentMonoclonal Antibody ProductionPharmaceutical Engineering
Area of Focus
Traditional Chinese Medicine | Quality Control | Pharmaceutical Engineering | Herbal Medicine | Analytical Methods | Process Optimization | Chromatography | Pharmacology | Chemical Engineering | Drug Development
