2017: Joined Zhejiang University as a researcher under the 'Hundred Talents Program'
2020: Promoted to Tenured Associate Professor at Zhejiang University
2023: Promoted to Tenured Professor at Zhejiang University
Published over 80 papers in international SCI journals, with over 40 as corresponding author in journals like Nature Nanotechnology, PNAS, Science Advances
Received funding from National Natural Science Foundation, Ministry of Science and Technology, National Biopharmaceutical Technology Innovation Center, Zhejiang Provincial Outstanding Youth Project
2017 - Present: Zhejiang University - Researcher, Associate Professor, Professor
Dean of the School of Pharmacy at Zunyi Medical University
JCR (Journal of Controlled Release) Emerging Leader Award
International Association of Advanced Materials Scientist Medal
Zhejiang University 2020 Top Ten Academic Progress Nomination
Research
Drug Delivery Biomaterials Gene Editing
Proinflammatory polarization of engineered heat-inducible macrophages reprogram the tumor immune microenvironment during cancer immunotherapy, Y. Xue, X. Yan, D. Li, S. Dong, Y. Ping, 2024
Supramolecular Genome Editing: Targeted Delivery and Endogenous Activation of CRISPR/Cas9 by Dynamic Host-Guest Recognition, B. Li, Q. Li, Z. Qi, Z. Li, X. Yan, Y. Chen, X. Xu, Q. Pan, Y. Chen, F. Huang, Y. Ping, 2024
An oncolytic virus–T cell chimera for cancer immunotherapy, Y. Chen, X. Chen, W. Bao, G. Liu, W. Wei, Y. Ping, 2024
Development of CRISPR/Cas Delivery Systems for In Vivo Precision Genome Editing, Y. Chen, Y. Ping, 2023
Targeted Delivery of PROTAC-based Prodrug Activated by Bond-Cleavage Bioorthogonal Chemistry for Microneedle-Assisted Cancer Therapy, J. Huang, Z. Yao, B. Li, Y. Ping, 2023
Non-Invasive Activation of Intratumoural Gene Editing for Improved Adoptive T-Cell Therapy in Solid Tumours, X. Chen, S. Wang, Y. Chen, H. Xin, S. Zhang, D. Wu, Y. Xue, M. Zha, H. Li, K. Li, Z. Gu, W. Wei, Y. Ping, 2023
A Dual-Specific CRISPR-Cas Nanosystem for Precision Therapeutic Editing of Liver Disorders, X. Xu, H. Tang, J. Guo, H. Xin, Y. Ping, 2022
Peptides as Molecular Trojan Horses, Y. Ping, 2022
A Duplex CRISPR-Cas9 Ribonucleoprotein Nanomedicine for Colorectal Cancer Gene Therapy, T. Wan, Q. Pan, C. Liu, J. Guo, B. Li, X. Yan, Y. Cheng, Y. Ping, 2021
Genome-Editing Prodrug: Targeted Delivery and Conditional Stabilization of CRISPR/Cas9 for Precision Therapy of Inflammatory Disease, X. Yan, Q. Pan, H. Xin, Y. Chen, Y. Ping, 2021
Rational Design of Poly(disulfide)s as a Universal Platform for Delivery of CRISPR/Cas9 Machineries toward Therapeutic Genome Editing, J. Guo, T. Wan, B. Li, Q. Pan, H. Xin, Y. Qiu, Y. Ping, 2021
Microneedle-Assisted Genome Editing: A Transdermal Strategy of Targeting NLRP3 by CRISPR/Cas9 for Synergistic Therapy of Inflammatory Skin Disorders, T. Wan, P. Qi, Y. Ping, 2021
Reprogramming Tumor Microenvironment through Second Near-Infrared Photothermal Genome Editing of PD-L1 mediated by Supramolecular Gold Nanorods for Enhanced Cancer Immunotherapy, H. Tang, X. Xu, Y. Chen, H. Xin, T. Wan, B. Li, H. Pan, D. Li, Y. Ping, 2021
Delivery of CRISPR/Cas9 Plasmids by Cationic Gold Nanorods: Impact of Aspect Ratio for Genome Editing and Treatment of Hepatic Fibrosis, Y. Chen, X. Chen, D. Wu, H. Xin, D. Chen, D. Li, H. Pan, C. Zhou, Y. Ping, 2021
Delivery of genome-editing biomacromolecules for treatment of lung genetic disorders, T. Wan, Y. Ping, 2021
Near-Infrared Engineering of Photothermal NanoCRISPR for Programmable Genome Editing, X. Chen, Y. Chen, H. Xin, T. Wan, Y. Ping, 2020
A synergistic optical strategy for enhanced deep-tumor penetration and therapy in the second near-infrared window, D. Wu, X. Chen, J. Zhou, Y. Chen, T. Wan, Y. Wang, A. Lin, Y. Ruan, Z. Chen, X. Song, W. Fang, H. Duan, Y. Ping, 2020
Genome editing of mutant KRAS through supramolecular polymer-mediated delivery of Cas9 ribonucleoprotein for colorectal cancer therapy, T. Wan, Y. Chen, Q. Pan, X. Xu, Y. Kang, X. Gao, F. Huang, C. Wu, Y. Ping, 2020
Bioengineering Bacterial Vesicle-Coated Polymeric Nanomedicine for Enhanced Cancer Immunotherapy and Metastasis Prevention, Q. Chen, M. Wu, G. Huang, G. Tang, Y. Ping, 2020
Off-Targeting of Base Editors: BE3 but not ABE induces substantial off-target single nucleotide variants, H. Xin, T. Wan, Y. Ping, 2019
A boronic acid-rich dendrimer with robust and unprecedented efficiency for cytosolic protein delivery and CRISPR/Cas9 gene editing, C. Liu, T. Wan, H. Wang, S. Zhang, Y. Ping, Y. Cheng, 2019
Material Solutions for Delivery of CRISPR/Cas-Based Genome Editing Tools: Current Status and Future Outlook, T. Wan, D. Niu, C. Wu, F-J Xu, G. Church, Y. Ping, 2019
Cationic Polymer‐Mediated CRISPR/Cas9 Plasmid Delivery for Genome Editing, Z. Zhang, T. Wan, Y. Chen, Y. Chen, H. Sun, T. Cao, Z. Songyang, G. Tang, C. Wu, Y. Ping, F. J. Xu, J. Huang, 2018
Reactive Oxygen Species (ROS)-Responsive Nanomedicine for RNAi-Based Cancer Therapy, Y. Li, H. Bai, H. Wang, Y. Shen, G. Tang, Y. Ping, 2018
A Cooperative Dimensional Strategy for Enhanced Nuclear-Targeted Delivery of Anticancer Drug, H. Wang, Y. Li, H. Bai, J. Shen, X. Chen, Y. Ping, Guping Tang, 2017
Targeting ETS1 with RNAi-based Supramolecular Nanoassemblies for Multidrug-Resistant Breast Cancer Therapy, M. Wu, X. Liu, W. Jin, Y. Li, Y. Li, Q. Hu, P. Chu, G. Tang, Y. Ping, 2017
Multiple Regulation of Cancer Multidrug Resistance through Lanthanide-Functionalized Supramolecular Polymeric Nanoparticles, W. Jin, Q. Wang, M. Wu, Y. Li, G. Tang, Y. Ping, P. K. Chu, 2017
Redox-Activatable ATP-Depleting Micelles with Dual Modulation Characteristics for Multidrug-Resistant Cancer Therapy, H. Wang, Y. Li, M. Zhang, D. Wu, Y. Shen, G. Tang, Y. Ping, 2017
A Redox-activated Light-up Nanomicelle for Precise Imaging-guided Cancer Therapy and Real-time Pharmacokinetic Monitoring, X. Liu, M. Wu, Q. Hu, H. Bai, S. Zhang, Y. Shen, G. Tang, Y. Ping, 2016
Structure-Invertible Nanoparticles for Triggered Co-Delivery of Nucleic Acids and Hydrophobic Drugs for Combination Cancer Therapy, K. Wang, Q. Hu, W. Zhu, M. Zhao, Y. Ping, G. Tang, 2015
Engineering Nanoparticle-Coated Bacteria as Oral DNA Vaccines for Cancer Immunotherapy, Q. Hu, M. Wu, C. Fang, C. Cheng, M. Zhao, W. Fang, P. K. Chu, Y. Ping, G. Tang, 2015
Area of Focus
Biomacromolecules | Non-Injection | Drug Delivery | Pharmaceutical Materials | Oral Nano Systems | In Vivo Transport | Nanoparticles | Bioavailability | Targeted Delivery | Drug Solubility
Area of Focus
Drug Delivery | Nanoparticles | Inflammation | Stroke | Depression | Tumor | Targeted Therapy | Chinese Medicine | Bioavailability | Formulation