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Shuqing Chen
Pharmaceutical Sciences
Zhejiang University
Zhejiang
Language: English, Chinese
Biotechnology
Drug Design
Precision Medicine
Neoantigens
Cancer Treatment
Therapeutic Antibodies
Immunotherapy
Genomics
Proteomics
Biochemistry
Areas of Focus
- Design of Novel Biotechnological Drugs
- New Technologies for Precision Medicine Based on Neoantigens
Work Experience
- 1983.8-1985.8 - Pharmacist: Yutao Zhangting Health Center, Zhejiang Province
- 1987.8-1990.10 - Assistant: Biochemistry Department, Zhejiang Medical University
- 1990.10-1993.12 - Lecturer: Biochemistry Department, Zhejiang Medical University
- 1995.8-1998.10 - Associate Professor: Biochemistry Department, Zhejiang University School of Medicine
- 1998.10-2003.3 - Professor, Vice Dean: Ningbo University School of Medicine
- 2003.4-present - Director, Professor, Doctoral Supervisor: Biotechnology Drug Research Laboratory, Zhejiang University School of Pharmacy
Academic Background & Achievements
- 1983 - Bachelor of Science: Zhejiang Medical University
- 1987 - Master of Medicine: Zhejiang Medical University
- 1999 - Doctor of Medicine: Zhejiang University
- 1993.12-1995.8 - Visiting Scholar: University of Kentucky, USA
- 2001.1-2002.1 - Postdoctoral Research: Cornell University, USA
Publications
- Emerging new therapeutic antibody derivatives for cancer treatment, Shijie Jin, Yanping Sun, Xiao Liang, Xinyu Gu, Jiangtao Ning, Yingchun Xu, Shuqing Chen, Liqiang Pan, 2021
- Real-Time Imaging of Cell-Surface Proteins with Antibody-Based Fluorogenic Probes, Wenchao Wang, Ying Zhang, Hong Zhao, Xinlei Zhuang, Haoting Wang, Kaifeng He, Wanting Xu, Yu Kang, Shuqing Chen, Su Zeng, Linghui Qian, 2021
- Optimization strategies for expression of a novel bifunctional anti-PD-L1/TGFBR2-ECD fusion protein, Zhang-zhao Gao, Cui Li, Gang Chen, Jun-jie Yuan, Ya-qiong Zhou, Jing-yu Jiao, Lei Nie, Jian Qi, Yong Yang, Shu-qing Chen, Hai-bin Wang, 2022
- Development of a recombinant RBD subunit vaccine for SARS-CoV-2, Yi-sheng Sun, Jing Jing Zhou, Ping Han Zhu, Fang Xu, Wenbin Zhao, Hang-Jing Lu, Zhen Wang, Shuqing Chen, Ping-Ping Yao, Jianmin Jiang, Zhan Zhou, 2021
- Facile generation of potent bispecific Fab via Sortase A and Click chemistry for cancer immunotherapy, Xuefei Bai, Wenhui Liu, Shijie Jin, Wenbin Zhao, Yingchun Xu, Zhan Zhou, Shuqing Chen, Liqiang Pan, 2021
- TSNAD v2.0: a one-stop software solution for tumor-specific neoantigen detection, Zhan Zhou, Jingcheng Wu, Jianan Ren, Wenfan Chen, Wenyi Zhao, Xun Gu, Jian Wu, Shuqing Chen, 2021
- CanDriS: posterior profiling of cancer-driving sites based on two-component evolutionary model, Wenyi Zhao, Jingwen Yang, Jingcheng Wu, Guoxing Cai, Yao Zhang, Jeffrey Haltom, Weijia Su, Michael J Dong, Shuqing Chen, Jian Wu, Zhan Zhou, Xun Gu, 2021
- A neoantigen-based peptide vaccine for patients with advanced pancreatic cancer refractory to standard treatment, Zheling Chen, Shanshan Zhang, Ning Han, Jiahong Jiang, Yunyun Xu, Dongying Ma, Lantian Lu, Xiaojie Guo, Min Qiu, Qinxue Huang, Huimin Wang, Fan Mo, Shuqing Chen, Liu Yang, 2021
- Soluble Expression of Fc-Fused T Cell Receptors Allows Yielding Novel Bispecific T Cell Engagers, Wen-Bin Zhao, Ying Shen, Wen-Hui Liu, Yi-Ming Li, Shi-Jie Jin, Ying-Chun Xu, Li-Qiang Pan, Zhan Zhou, Shu-Qing Chen, 2021
- A novel biparatopic EGFR-targeting nanobody drug conjugate displays potent anticancer activity in solid tumor models, Jiansheng Fan, Xinlei Zhuang, Xiaoyue Yang, Yingchun Xu, Zhan Zhou, Liqiang Pan, Shuqing Chen, 2021
- Synthetic Multi-epitope Neoantigen DNA Vaccine for Personalized Cancer Immunotherapy, Xiaoyue Yang, Jiansheng Fan, Zhiming Ma, Jin Huang, Ying Zhang, Zhan Zhou, Fan Mo, Xuerong Liu, Hong Yuan, Yingchun Xu, Liqiang Pan, Shuqing Chen, 2021
- Multi-epitope vaccine design using an immunoinformatics approach for COVID-19, Ye Feng, Haiping Jiang, Min Qiu, Liang Liu, Shengmei Zou, Yun Li, Qianpeng Guo, Ning Han, Yingqiang Sun, Kui Wang, Xinlei Zhuang, Shanshan Zhang, Shuqing Chen, Fan Mo, 2021
- A novel genomic classification system of gastric cancer via integrating multidimensional genomic characteristics, Haiyong Wang, Yongfeng Ding, Yanyan Chen, Junjie Jiang, Yiran Chen, Jun Lu, Mei Kong, Fan Mo, Yingying Huang, Wenyi Zhao, Ping Fang, Xiangliu Chen, Xiaodong Teng, Nong Xu, Yimin Lu, Xiongfei Yu, Zhongqi Li, Jing Zhang, Haohao Wang, Xuanwen Bao, Donghui Zhou, Tianhua Zhou, Zhan Zhou, Shuqing Chen, Lisong Teng, 2021
- Specifically inhibit tumor growth by T cell receptor-drug conjugates targeting intracellular cancer-testis antigen NY-ESO-1/LAGE-1, Chi-Xiao Qiu, Xue-Fei Bai, Ying Shen,
Awards
- 2016 - Outstanding Doctoral Dissertation Nomination: Research on the Design and Specific Antitumor Effects of TRAIL Conjugates
- 2015 - Second Prize, Higher Education Science and Technology Progress Award: Research on Key Technologies and Models for ADMET Drug Evaluation
- 2014 - Second Prize, Chinese Pharmaceutical Association Science and Technology Award: Research on Key Technologies and Models for ADMET Drug Evaluation
- 2014 - Excellent Social Science Book Award: Pharmacogenomics - Application in Patient Care
- 2012 - Second Prize, Chinese Pharmaceutical Association Science and Technology Award: Research on Chiral Drug Analysis and Stereoselective Metabolism
- 2012 - Second Prize, Zhejiang Science and Technology Progress Award: Research on Chiral Drug Analysis and Metabolism
- 2007 - First Prize, Zhejiang Traditional Chinese Medicine Science and Technology Innovation Award: Research on Screening Technology Platform for Metabolic Activity of Traditional Chinese Medicine and Natural Drugs
- 2004 - First Prize, Zhejiang Medical and Health Science and Technology Innovation Award: Research on Clinical Value of Drug Metabolizing Enzyme Genotypes
- 2004 - Second Prize, Zhejiang Science and Technology Progress Award: Research on Clinical Value of Drug Metabolizing Enzyme Genotypes
- 2000 - Second Prize, Ningbo University Teaching Achievement Award: Role of General Medicine in Higher Medical Education
- 1999 - Third Prize, Zhejiang Medical Science and Technology Progress Award: Identification and Detection Method of Tumor Susceptibility Gene CYP2C19
- 1998 - Third Prize, Zhejiang Science and Technology Progress Award: Polymorphism of Cytochrome P450 2D6 Gene and Its Clinical Significance
- 1996 - Second Prize, Zhejiang Medical University Teaching Achievement Award: Reform and Practice of Biochemical Experiment Teaching
- 1993 - Second Prize, Zhejiang Medical University Teaching Achievement Award: Reform and Practice of Basic Medical Experiment Teaching
