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Lihua Luo
luolihua@zju.edu.cn
Chinese, English
Zhejiang
Zhejiang University
Pharmaceutical Sciences
  • 2015.09 - 2019.03 PhD: Zhejiang University
  • Achievement: Designed a peptide microsphere with sustained release behavior for treating primary and distal tumors
  • Achievement: Researched photothermal ablation combined with anti-PD-1 therapy for metastatic tumors
  • Achievement: Explored enhancing tumor immunotherapy by improving tumor hypoxia and acidic microenvironment
  • 2021.11 - Present - Zhejiang University - Distinguished Researcher
  • 2019.04 - 2021.11 - Zhejiang University - Postdoctoral Researcher/Assistant Researcher
  • National Natural Science Foundation Youth Fund: 240,000 RMB (Ongoing)
  • China Postdoctoral (Pre-Station) Special Funding: 180,000 RMB (Completed)
  • China Postdoctoral 67th Batch General Funding: 80,000 RMB (Completed)
  • Zhejiang Province Postdoctoral Priority Funding: 50,000 RMB (Completed)
  • Zhejiang University Basic Research Funding: 50,000 RMB (Ongoing)
Design and application of targeted, sustained-release formulations
Photothermal immunotherapy for tumors
Construction and application of tumor/virus vaccine carriers
  • The Effect of Blood Velocity in Solid Tumor on Intratumorally Accumulation and Penetration of Nanocarriers and Drugs, Sijie Wang, Junlei Zhang, Huihui Liu, Xuemeng Guo, Yichao Lu, Guannan Guan, Zhenyu Luo, Mengshi Jiang, Qing Lin, Huanli Zhou, Xiaoqi Zhao, Lihua Luo*, Jian You*, 2023
  • The application of nanoparticle-based imaging and phototherapy for female reproductive organs diseases, Lihua Luo, Huanli Zhou, Sijie Wang, Mei Pang, Junlei Zhang, Yilong Hu, Jian You*, 2023
  • Neutrophil Hitchhiking for Drug Delivery to the Bone Marrow, Zhenyu Luo, Yichao Lu, Yingying Shi, Mengshi Jiang, Xinyu Shan, Xiang Li, Junlei Zhang, Bing Qin, Xu Liu, Xuemeng Guo, Jiaxin Huang, Yu Liu, Sijie Wang, Qingpo Li, Lihua Luo*, Jian You*, 2023
  • A clinically-achievable injectable and sprayable in-situ lyotropic liquid crystalline platform in treating hormone-sensitive and castration-resistant prostate cancer, Shan, Xinyu; Li, Xiang ; Luo, Zhenyu; Lin, Qing; Lu, Yichao; Jiang, Mengshi; Zhang, Junlei ; Huang, Jiaxin; Xie, Lin ; Guo, Xuemeng; Liu, Xu; Shi, Yingying ; Liu, Yu; Yin, Hang; Yang, Fuchun; Luo, Lihua*; You, Jian*, 2023
  • Recruiting T cells and sensitizing tumors to NKG2D immune surveillance for robust antitumor immune response, Xiang Li, Xuemeng Guo, Jiaxin Huang, Qing Lin, Bing Qin, Mengshi Jiang, Xinyu Shan, Zhenyu Luo, Junlei Zhang, Yingying Shi, Yichao Lu, Xu Liu, Yongzhong Du, Fuchun Yang, Lihua Luo*, Jian You*, 2023
  • Preventing Acute Lung Injury from Progressing to Pulmonary Fibrosis by Maintaining ERS Homeostasis Through a Multistage Targeting Nanomicelle, Lihua Luo, Zhenyu Luo, Junlei Zhang, Xu Liu, Jiaxin Huang, Sijie Wang, Hang Yin, Xuemeng Guo, Yilong Hu, Yichao Lu, Xinyu Shan, Huihui Liu, Yingying Shi, Yongzhong Du, Fuchun Yang, Jian You*, 2022
  • Reactivation of dysfunctional dendritic cells by a stress-relieving nanosystem resets anti-tumor immune landscape, Yichao Lu, Yingying Shi, Zhenyu Luo, Xuemeng Guo, Mengshi Jiang, Xiang Li, Junlei Zhang, Chunqi Zhu, Hang Yin, Bing Qin, Xu Liu, Jiaxin Huang, Yongzhong Du, Lihua Luo*, Jian You*, 2022
  • ER-targeting PDT converts tumor into in-situ therapeutic tumor vaccine, Liu, Xu; Liu, Yu; Li, Xiang; Huang, Jiaxin; Guo, Xuemeng; Zhang, Junlei; Luo, Zhenyu; Shi, Yingying; Jiang, Mengshi; Qin, Bing; Du, Yong-Zhong; Luo, Lihua*; You, Jian*, 2022
  • A Therapeutic DC Vaccine with Maintained Immunological Activity Exhibits Robust Anti-Tumor Efficacy, Yichao Lu, Yingying Shi, Yu Liu, Zhenyu Luo, Junlei Zhang, Mengshi Jiang, Xiang Li, Xu Liu,Xuemeng Guo, Bing Qin, Hang Yin, Yongzhong Du, Yunqing Qiu, Yan Lou, Guannan Guan, Lihua Luo*, Jian You*, 2022
  • Arginine supplementation targeting tumor-killing immune cells reconstructs tumor microenvironment and enhances antitumor immune response, Zhang, Junlei ; Wang, Sijie; Guo, Xuemeng; Lu, Yichao; Liu, Xu; Jiang, Mengshi; Li, Xiang ; Qin, Bing; Luo, Zhenyu; Liu, Huihui; Li, Qingpo; Du, Yong-Zhong; Luo, Lihua*; You, Jian*, 2022
  • Enhanced immune memory through a constant Photothermal-Metabolism regulation for Cancer Prevention and Treatment, Lihua Luo, Xiang Li, Junlei Zhang, Chunqi Zhu, Mengshi Jiang, Zhenyu Luo, Bing Qin, Yanqing Wang, Bin Chen, Yongzhong Du, Yan Lou, Jian You*, 2021
  • Regulating Immune Memory and Reversing Tumor Thermotolerance through a Step-by-Step Starving-Photothermal therapy, Lihua Luo; Bing Qin; Mengshi Jiang; Lin Xie; Zhenyu Luo; Xuemeng Guo; Junlei Zhang; Xiang Li; Chunqi Zhu; Yongzhong Du; Ling Peng; Jian You*, 2021
  • Laser Immunotherapy in Combination with Perdurable PD-1 Blocking for Treatment of Metastatic Tumor, Lihua Luo, Chunqi Zhu, Hang Yin, Mengshi Jiang, Junlei Zhang, Bing Qin, Zhenyu Luo, Xiaoling Yuan, Jie Yang, Wei Li, Yongzhong Du, Jian You*, 2018
  • Perdurable Anti-PD-1 Immunotherapy Together with Photothermal Ablation against Malignant and Distant Tumors, Lihua Luo, Chunqi Zhu, Jie Yang, XiaomengGuo, Wei Li, Xiaoyi Yin, Mengshi Jiang, Bing Qin, Xiaoling Yuan, Hang Yin, Qingpo Li, Yongzhong Du, Jian You*, 2018
  • Pharmacokinetics and tissue distribution of docetaxel liposome mediated by a novel galactosylated cholesterol derivatives synthesized by lipase-catalyzed esterification in non-aqueous phase, Lihua Luo, Pin jing, Zheng, Hua Nie, Yu chao Chen, Dan Tong, Jin Chen &Yi Chen, 2016
  • Inhibiting Hypoxia and Chemotherapy-Induced Cancer Cell Metastasis under a Valid Therapeutic Effect by an Assistance of Biomimetic Oxygen Delivery, Meng Shi Jiang, Xiao Yi Yin, Bing Qin, Shao Yan Xuan, Xiao Ling Yuan, Hang Yin, Chunqi Zhu, Xiang Li, Jie Yang, Yong-Zhong Du, Lihua Luo*, and Jian You*, 2019
  • Perdurable PD-1 blockage awakes anti-tumor immunity suppressed by precise chemotherapy, Mengshi Jiang, Wei Li, Chunqi Zhu, Xiang Li, Junlei Zhang, Zhenyu Luo, Bing Qin, Yongzhong Du, Lihua Luo*, Jian You*, 2021
  • Targeting photodynamic and photothermal therapy to the endoplasmic reticulum enhances immunogenic cancer cell death, Wei Li#, Jie Yang#, Lihua Luo#, Mengshi Jiang, Bing Qin, Hang Yin, Chunqi Zhu, Xiaoling Yuan, Junlei Zhang, Zhenyu Luo, Yong-Zhong Du, Qingpo Li Yan Lou, Yunqing Qiu, Jian You*, 2019
  • Cocktail strategy for ‘cold’ tumors therapy via active recruitment of CD8+ T cells and enhancing their function, Xiang Li#, Lihua Luo#, Mengshi Jiang, Chunqi Zhu, Yingying Shi, Junlei Zhang, Zhenyu Luo, Xuemeng Guo, Bing Qin, Yichao Lu, Xinyu Shan, Yu Liu, Yongzhong Du, Ling Peng*, Jian You*, 2021
Targeted Therapy Sustained Release Formulations Photothermal Therapy Immunotherapy Tumor Vaccine Virus Nanoparticles Drug Delivery

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