Achievement: Designed a peptide microsphere with sustained release behavior for treating primary and distal tumors
Achievement: Researched photothermal ablation combined with anti-PD-1 therapy for metastatic tumors
Achievement: Explored enhancing tumor immunotherapy by improving tumor hypoxia and acidic microenvironment
2021.11 - Present - Zhejiang University - Distinguished Researcher
2019.04 - 2021.11 - Zhejiang University - Postdoctoral Researcher/Assistant Researcher
National Natural Science Foundation Youth Fund: 240,000 RMB (Ongoing)
China Postdoctoral (Pre-Station) Special Funding: 180,000 RMB (Completed)
China Postdoctoral 67th Batch General Funding: 80,000 RMB (Completed)
Zhejiang Province Postdoctoral Priority Funding: 50,000 RMB (Completed)
Zhejiang University Basic Research Funding: 50,000 RMB (Ongoing)
Research
Design and application of targeted, sustained-release formulations Photothermal immunotherapy for tumors Construction and application of tumor/virus vaccine carriers
The Effect of Blood Velocity in Solid Tumor on Intratumorally Accumulation and Penetration of Nanocarriers and Drugs, Sijie Wang, Junlei Zhang, Huihui Liu, Xuemeng Guo, Yichao Lu, Guannan Guan, Zhenyu Luo, Mengshi Jiang, Qing Lin, Huanli Zhou, Xiaoqi Zhao, Lihua Luo*, Jian You*, 2023
The application of nanoparticle-based imaging and phototherapy for female reproductive organs diseases, Lihua Luo, Huanli Zhou, Sijie Wang, Mei Pang, Junlei Zhang, Yilong Hu, Jian You*, 2023
Neutrophil Hitchhiking for Drug Delivery to the Bone Marrow, Zhenyu Luo, Yichao Lu, Yingying Shi, Mengshi Jiang, Xinyu Shan, Xiang Li, Junlei Zhang, Bing Qin, Xu Liu, Xuemeng Guo, Jiaxin Huang, Yu Liu, Sijie Wang, Qingpo Li, Lihua Luo*, Jian You*, 2023
Enhanced immune memory through a constant Photothermal-Metabolism regulation for Cancer Prevention and Treatment, Lihua Luo, Xiang Li, Junlei Zhang, Chunqi Zhu, Mengshi Jiang, Zhenyu Luo, Bing Qin, Yanqing Wang, Bin Chen, Yongzhong Du, Yan Lou, Jian You*, 2021
Regulating Immune Memory and Reversing Tumor Thermotolerance through a Step-by-Step Starving-Photothermal therapy, Lihua Luo; Bing Qin; Mengshi Jiang; Lin Xie; Zhenyu Luo; Xuemeng Guo; Junlei Zhang; Xiang Li; Chunqi Zhu; Yongzhong Du; Ling Peng; Jian You*, 2021
Laser Immunotherapy in Combination with Perdurable PD-1 Blocking for Treatment of Metastatic Tumor, Lihua Luo, Chunqi Zhu, Hang Yin, Mengshi Jiang, Junlei Zhang, Bing Qin, Zhenyu Luo, Xiaoling Yuan, Jie Yang, Wei Li, Yongzhong Du, Jian You*, 2018
Perdurable Anti-PD-1 Immunotherapy Together with Photothermal Ablation against Malignant and Distant Tumors, Lihua Luo, Chunqi Zhu, Jie Yang, XiaomengGuo, Wei Li, Xiaoyi Yin, Mengshi Jiang, Bing Qin, Xiaoling Yuan, Hang Yin, Qingpo Li, Yongzhong Du, Jian You*, 2018
Pharmacokinetics and tissue distribution of docetaxel liposome mediated by a novel galactosylated cholesterol derivatives synthesized by lipase-catalyzed esterification in non-aqueous phase, Lihua Luo, Pin jing, Zheng, Hua Nie, Yu chao Chen, Dan Tong, Jin Chen &Yi Chen, 2016
Inhibiting Hypoxia and Chemotherapy-Induced Cancer Cell Metastasis under a Valid Therapeutic Effect by an Assistance of Biomimetic Oxygen Delivery, Meng Shi Jiang, Xiao Yi Yin, Bing Qin, Shao Yan Xuan, Xiao Ling Yuan, Hang Yin, Chunqi Zhu, Xiang Li, Jie Yang, Yong-Zhong Du, Lihua Luo*, and Jian You*, 2019
Targeting photodynamic and photothermal therapy to the endoplasmic reticulum enhances immunogenic cancer cell death, Wei Li#, Jie Yang#, Lihua Luo#, Mengshi Jiang, Bing Qin, Hang Yin, Chunqi Zhu, Xiaoling Yuan, Junlei Zhang, Zhenyu Luo, Yong-Zhong Du, Qingpo Li Yan Lou, Yunqing Qiu, Jian You*, 2019
Cocktail strategy for ‘cold’ tumors therapy via active recruitment of CD8+ T cells and enhancing their function, Xiang Li#, Lihua Luo#, Mengshi Jiang, Chunqi Zhu, Yingying Shi, Junlei Zhang, Zhenyu Luo, Xuemeng Guo, Bing Qin, Yichao Lu, Xinyu Shan, Yu Liu, Yongzhong Du, Ling Peng*, Jian You*, 2021
Area of Focus
Pharmaceutics | Biopharmaceutics | Pharmacokinetics | Drug Delivery | Brain Targeting | Nanoparticles | Nasal Delivery | New Drug Development | In Vivo Evaluation | In Vitro Evaluation
Area of Focus
Theranostics | Formulations | Drug Delivery | Cancer | Radiotherapy | Chemotherapy | Immunotherapy | New Drug Formulations | Intelligent Delivery | Nanomedicine