Xiaoda Yang

xyang@bjmu.edu.cn

Chinese, English

Beijing

Peking University

Pharmaceutical Sciences

• 1984-1988 Bachelor of Science: Peking University, Department of Chemistry
• 1988-1994 Doctor of Science: Peking University, Department of Chemistry, Analytical Chemistry
• Published over 100 papers in domestic and international academic journals
• Received 4 Chinese invention patents
• Chief editor of a national planning textbook set for the 'Eleventh Five-Year Plan'
• Received the New Century Excellent Talents Support Program from the Ministry of Education in 2004
• Received the Second Prize of Beijing Science and Technology Progress Award in 2002

• 1994-1996 - Peking University Health Science Center, School of Pharmaceutical Sciences, Department of Inorganic Chemistry - Postdoctoral Research
• 1997-2000 - University of Kansas, School of Pharmacy, Department of Medicinal Chemistry - Postdoctoral Research
• 2000.8-Present - Peking University Health Science Center, School of Pharmaceutical Sciences, Department of Chemical Biology - Faculty
• 2003-Present - Peking University Health Science Center, School of Pharmaceutical Sciences, Department of Chemical Biology - Professor
• 2006-2010 - Peking University Health Science Center, School of Pharmaceutical Sciences, Department of Chemical Biology - Deputy Director

• New Century Excellent Talents Support Program (2004): Ministry of Education
• Second Prize of Beijing Science and Technology Progress Award (2002): Beijing

Metabolic diseases (cardiovascular diseases, neurodegenerative diseases, osteoporosis, diabetes) related to metal metabolism and cell signal transduction
Reactive oxygen metabolism in cells, antioxidant response mechanisms, and heavy metal exclusion
Quantitative structure-ADMET relationship (QSPR) studies of inorganic and mineral traditional Chinese medicine
Discovery and development of chemopreventive drugs for tumors and metabolic diseases from food and traditional Chinese medicine

• Synthesis, characterization and anti-diabetic therapeutic potential of novel aminophenol-derivatized nitrilotriacetic acid vanadyl complexes, Wang N, Wang Z, Niu X, Yang X, 2015
• The permeability and transport mechanism of graphene quantum dots (GQDs) across the biological barrier, Wang X, Lei R, Huang H, Wang N, Yuan L, Xiao R, Bai L, Li X, Li L, Yang X, 2015
• Is the Hypoglycemic Action of Vanadium Compounds Related to the Suppression of Feeding?, Huang M, Wu Y, Wang N, Wang Z, Zhao P, Yang X, 2014
• Vanadyl acetylacetonate upregulates PPARγ and adiponectin expression in differentiated rat adipocytes, Yaling Wu, Meiling Huang, Pan Zhao, Xiaoda Yang, 2013
• Vanadium compounds modulate PPARγ activity primarily by increasing PPARγ protein levels in mouse insulinoma NIT-1 cells, Zhao P, Yang X, 2013
• Europium complexes as novel indicators of paracellular diffusion, Xu Z, Zhang CY, Zhang Y, Yang X, 2012
• Vanadyl bis-acetylacetonate protected β cell from palmitate-induced cell death through unfolded protein response pathway, Gao Z, Zhang C, Yu S, Yang X, Wang K, 2011
• A new salicylic acid-derivatised kojic acid vanadyl complex: Synthesis, Characterization and Anti-diabetic Therapeutic Potential, Wei Y, Zhang C, Zhao P, Yang X, Wang K, 2011
• Brain derived neutrotrophic factor protects neurons from GdCl3-induced impairment in neuron-astrocyte co cultures, Xia Q, Feng X-D, Yuan L, Wang K, Yang X, 2010
• Vanadium compounds induced mitochondria permeability transition pore (PTP) opening related to oxidative stress, Zhao Y, Ye L, Liu H, Xia Q, Zhang Y, Yang X, Wang K, 2010
• Studies of intestinal permeability of 36 flavonoids using Caco-2 cell monolayer model, Tian XJ, Yang XW, Yang X, Wang K, 2009
• La3+ binds to BiP/GRP78 and induces unfolded protein response in HepG2 cells, Shen C, Li Z, Yang X, Wang K, 2008
• Copper ions inhibit S-Adenosylhomocysteine hydrolase by causing dissociation of NAD+ cofactor, Li M, Li Y, Chen J, Wei W, Pan X, Liu J, Liu Q, Leu W, Zhang L, Yang X, Lu J, Wang K, 2007
• La3+-Induced Extracellular Signal-Regulated Kinase (ERK) Signaling via a Metal-Sensing Mechanism Linking Proliferation and Apoptosis in NIH 3T3 Cells, Yu S, Hu J, Yang X, Wang K, Qian ZM, 2006
• The Permeability and Cytotoxicity of Insulin-mimetic Vanadium (III, IV, V)-Dipicolinate Complexes, Zhang Y, Yang X, Wang K, Crans DC, 2006
• La3+-Promoted Proliferation Could Be Interconnected with Apoptosis in NIH 3T3 Cells, Yu S, Yuan L, Yang X, Wang K, Qian Z, 2005
• The Permeability and Cytotoxicity of Insulin-mimetic Vanadium Compounds, Yang X-G, Yang X, Yuan L, Wang K, Crans DC, 2004
• La3+, Gd3+ and Yb3+ induced changes in mitochondrial structure, membrane permeability, cytochrome C release and intracellular ROS level, Liu H, Yuan L, Yang X, Wang K, 2003