2000.9 – 2003.12, Ph.D. in Chemical Biology, Peking University, Advisors: Kui Wang, Xiaoda Yang
1997.9 – 2000.7, M.Sc. in Chemistry, Huazhong University of Science and Technology, Advisors: Huibi Xu, Changlin Liu
1992.9 – 1996.7, B.Sc. in Chemical Engineering, Sichuan University of Light Industry, Advisor: Shu Wang
Beijing University Green Leaf Biomedical Outstanding Young Scholar Award
Beijing University Excellent Talent Reward Program Young Scholar Award
2018.1 - Present, Associate Professor, Doctoral Supervisor, Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University
2008.12 - 2017.12, Associate Professor, Master's Supervisor, Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University
2004.12 – 2008.12, Postdoctoral Researcher, Rutgers, The State University of New Jersey, USA
2003.12 - 2004.12, Assistant to General Manager, Chengdu Xinkang Pharmaceutical Co., Ltd.
Beijing University Green Leaf Biomedical Outstanding Young Scholar Award
Beijing University Excellent Talent Reward Program Young Scholar Award
Research
Stress signal transduction mechanisms in cells and organisms Cellular and molecular mechanisms in cancer and metabolic diseases Biomarkers and intervention targets for disease prevention and treatment Personalized prediction of disease progression Targeted intervention or preventive treatment using natural or synthetic substances
Dibenzoylmethane Protects Against CCl4-Induced Acute Liver Injury by Activating Nrf2 via JNK, AMPK, and Calcium Signaling, Cao M, Wang H, Guo L, Yang S, Liu C, Khor TO, Yu S*, Kong AN, 2017
An unusual spinaceamine-bearing pregnane from a soft coral Scleronephthya sp. inhibits the migration of tumor cells, Cheng W, Liu Z, Yu Y, van Ofwegen L, Proksch P, Yu S*, Lin W*, 2017
A novel triazolonaphthalimide induces apoptosis and inhibits tumor growth by targeting DNA and DNA-associated processes, Ji L, Yang S, Li S, Liu S, Tang S, Liu Z, Meng X*, Yu S*, 2017
Licoricidin inhibits the growth of SW480 human colorectal adenocarcinoma cells in vitro and in vivo by inducing cycle arrest, apoptosis and autophagy, Ji S, Tang S, Li K, Li Z, Liang W, Qiao X, Wang Q, Yu S*, Ye M*, 2017
Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra, Li K, Ji S, Song W, Kuang Y, Lin Y, Tang S, Cui Z, Qiao X, Yu S, Ye M*, 2017
Activation of Nrf2-ARE signaling mitigates cyclophosphamide-induced myelosuppression, Que L, He L, Yu C, Yin W, Ma L, Cao B*, Yu S*, 2016
Isocoumarin Derivatives from the Sponge-Associated Fungus Peyronellaea glomerata with Antioxidant Activities, Zhao, Y., Liu, D., Proksch, P., Yu, S.*, Lin, W.*, 2016
Synthesis, anti-cancer evaluation of benzenesulfonamide derivatives as potent tubulin-targeting agents, Yang, J., Yang, S., Zhou, S., Lu, D., Ji, L., Li, Z., Yu, S.*, Meng, X.*, 2016
Antioxidative phenolic compounds from a marine-derived fungus Aspergillus versicolor, Wu ZH, Wang YR, Liu D, Proksch P, Yu SW*, Lin WH*, 2016
Bioactive Constituents of Glycyrrhiza uralensis (Licorice): Discovery of the Effective Components of a Traditional Herbal Medicine, Ji S, Li Z, Song W, Wang Y, Liang W, Li K, Tang S, Wang Q, Qiao X, Zhou D, Yu S*, Ye M*, 2016
Cancer Prevention Research in China, Yu S*, Yang CS, Li J, You W, Chen JG, Cao Y, Dong Z, Qiao YL, 2015
Epigenetic regulation of Keap1-Nrf2 signaling, Guo Y, Yu S*, Zhang C, Tony Kong AN, 2015
Anti-H1N1 virus, cytotoxic and Nrf2 activation activities of chemical constituents from Scutellaria baicalensis, Ji S, Li R, Wang Q, Miao WJ, Li ZW, Si LL, Qiao X, Yu SW, Zhou DM, Ye M, 2015
Synthesis and biological evaluation of thiabendazole derivatives as anti-angiogenesis and vascular disrupting agents, Zhang C, Zhong B, Yang S, Pan L, Yu S, Li Z, Li S, Su B, Meng X, 2015
Metformin activates Nrf2 signaling and induces the expression of antioxidant genes in skeletal muscle and C2C12 myoblasts, Yang SM, Ji LY, Que LL, Wang K, Yu SW*, 2014
Amicoumacins from the marine-derived bacterium Bacillus sp. with the inhibition of NO production, Jian Bai, Dong Liu, Siwang Yu, Peter Proksch, Wenhan Lin, 2014
Synthesis and structure-activity relationship of 4-azaheterocycle benzenesulfonamide derivatives as new microtubule-targeting agents, Yang J, Zhou S, Ji L, Zhang C, Yu S, Li Z, Meng X, 2014
Synthesis and cytotoxicity evaluation of naphthalimide derived N-mustards, Lou Q, Ji L, Zhong W, Li S, Yu S*, Li Z, Meng X*, 2014
Biotransformation of 20(R)-panaxadiol by the fungus Rhizopus chinensis, Lin XH, Cao MN, He WN, Yu SW*, Guo DA, Ye M*, 2014
IC5, a dithiocarbamate derivative, inhibits colon cancer cell proliferation in vitro and colitis-associated colorectal carcinogenesis in vivo, Ma WW, Tang SN, Cao MN, Ge ZM, Li RT, Yu SW*, 2014
Isoangustone A induces apoptosis in SW480 human colorectal adenocarcinoma cells by disrupting mitochondrial functions, Huang W, Tang S, Qiao X, Ma W, Ji S, Wang K, Ye M*, Yu S*, 2014
Upregulation of Nrf2 regulated gene expression by tBHQ alleviates cyclophosphamide-induced hematotoxicity in mice, Que LL, Wang XZ, Qian PZ, Cao BS, Wang K, Yu SW*, 2014
Identification of Key Licorice Constituents Which Interact with Cytochrome P450: Evaluation by LC/MS/MS Cocktail Assay and Metabolic Profiling, Qiao X, Ji S, Yu SW, Lin XH, Jin HW, Duan YK, Zhang LR, Guo DA, Ye M*, 2014
Epigenetic Modifications of Nrf2 by 3,3'-diindolylmethane In Vitro in TRAMP C1 Cell Line and In Vivo TRAMP Prostate Tumors, Wu TY, Khor TO, Su ZY, Saw CL, Shu L, Cheung KL, Huang Y, Yu S, Kong AN, 2013
Cancer Chemoprevention in China, Yu S*, Yang CS, 2013
The nuclear cofactor RAC3/AIB1/SRC-3 enhances Nrf2 signaling by interacting with transactivation domains, Kim JH, Yu S, Chen JD, Kong AN*, 2013
Vanadyl bisacetylacetonate protects β cells from palmitate-induced cell death through the unfolded protein response pathway, Gao Z, Zhang C, Yu S*, Yang X*, Wang K, 2011
The regulation and functions of transcription factor Nrf2 in cancer chemoprevention and chemoresistance, Que LL, Wang HX, Cao BS, Yang XD, Wang K, Yu SW*, 2011
Nrf2 Expression Is Regulated by Epigenetic Mechanisms in Prostate Cancer of TRAMP Mice, Yu S, Khor TO, Cheung K-L, Li W, Wu T-Y, Huang Y, Foster BA, Kan YW, Kong AN*, 2010
