New techniques and methods in drug analysis and their applications in the biomedical field Biomarkers and drug efficacy evaluation in the study of disease occurrence, development, and outcome through multi-omics research
Novel electrochemical biosensors for investigating the interactions between atezolizumab and PD-1/PD-L1 and screening their small-molecular inhibitors, Juncheng Zou, Cong Li, Xinyue Zhang, Tao Huang, Nurmuhammat Kehriman, Wen Kuang, Xin Hu, Youqi Yan, Xiaomei Ling, 2022
Multi-factor combined biomarker screening strategy to rapidly diagnose Alzheimer’s disease and evaluate drug effect based on a rat model, Yanmeng Liu, Xinyue Zhang, Weiwei Lin, Nurmuhammat Kehriman, Wen Kuang, Xiaomei Ling, 2022
Novel Cells-Based Electrochemical Sensor for Investigating the Interactions of Cancer Cells with Molecules and Screening Multitarget Anticancer Drugs, Cong Li, Yinzhu Cui, Jinyu Ren, Juncheng Zou, Wen Kuang, Xiaozhi Sun, Xin Hu, Youqi Yan, Xiaomei Ling, 2021
A strategy for population pharmaceutical quality assessment based on quality by design, Yu Zhao, Changqin Hu, Shangchen Yao, Lihui Yin, Xiaomei Ling, 2021
Detection of membrane receptors on per tumor cell by nonimmobilized cell capillary electrophoresis and a mathematic model, Ruijun Wu, Chunsu Liang, Juncheng Zou, Cong Li, Xiaomei Ling, 2021
Biomimetic cell-cell adhesion capillary electrophoresis for studying Gu-4 antagonistic interaction between cell membrane receptor and ligands, Yiran Zhao, Linghan Jia, Chunsu Liang, Cong Li, Meina Li, Xiaomei Ling, 2020
A novel strategy for rapidly and accurately screening biomarkers based on ultraperformance liquid chromatography-mass spectrometry metabolomics data, Cong Li, Jianmei Zhang, Ruijun Wu, Yi Liu, Xin Hu, Youqi Yan, Xiaomei Ling, 2019
MNPs@anionic MOFs/ERGO with the size selectivity for the electrochemical determination of H2O2 released from living cells, Cong Li, Ruijun Wu, Juncheng Zou, Tingting Zhang, Sufang Zhang, Zhiquan Zhang, Xin Hu, Youqi Yan, Xiaomei Ling, 2018
Mechanisms of the active components from Korean pine nut preventing and treating D-galactose-induced aging rats, Jianmei Zhang, Weiwei Lin, Ruijun Wu, Yanmeng Liu, Kai Zhu, Jinyu Ren, Sufang Zhang, Xiaomei Ling, 2018
Nonimmobilized Biomaterial Capillary Electrophoresis for Screening Drugs Targeting Human Glucose Transporter 1, Ruijun Wu, Kai Zhu, Xiaodan Zhang, Sufang Zhang, Yanmeng Liu, Jinyu Ren, Cong Li, Min Ye, Xiaomei Ling, 2017
Studies on diagnostic biomarkers and therapeutic mechanism of Alzheimer’s disease through metabolomics and hippocampal proteomics, Weiwei Lin, Jianmei Zhang, Haisong yang, Xiaobo Hu, Yanmeng Liu, Ruijun Wu, Xiaomei Ling, 2017
Metabolic profiling study on potential toxicity and immunotoxicity-biomarker discovery in rats treated with cyclophosphamide using HPLC-ESI-IT-TOF-MS, Jing Li, Wensi Lin, Weiwei Lin, Peng Xu, Jianmei Zhang, Haisong Yang, Xiaomei Ling, 2015
Rapid screening and identification of active ingredients in licoriceextract interacting with V3 loop region of HIV-1 gp120 using ACE and CE-MS, Zhongjie Li, Yiran Zhao, Weiwei Li, Xiaobo Hu, MinYe, Xiaodan Zhang, Xiaomei Ling, 2015
The effects of piracetam on heroin-induced CPP and neuronal apoptosis in rats, Peng Xu, Min Li, Yanping Βai, Wei Lu, Xiaomei Ling, Weidong Li, 2015
Quantitative evaluation of interactions between Kv4.3 N-terminus and its auxilary subunit KchIPs by affinity capillary electrophoresis, Meina Li, Lei Lei, Linghan Jia, Xiaomei Ling, Jianmei Zhang, Yiran Zhao, Kewei Wang, 2014
Urine metabonomics analysis of the toxic effects of TM208 in rats by HPLC-IT-TOF/MS, Haisong Yang, Wensi Lin, Jianmei Zhang, Weiwei Lin, Peng Xu, Jing Li, Xiaomei Ling, 2014
CCR4 Expressing Cell Cultured Adherently on a Capillary Wall as the Stationary Phase for Ligand Screening by ACE, Pazilaiti.Yakufu, Hui Qi, Xiaomei Ling, Wenjing Chen, Ying Wang, 2013
Evaluation of the effect of TM208 on the activity of five cytochrome P450 enzymes using on-line solid-phase extraction HPLC-DAD: A cocktail approach, Wensi Lin, Jianmei zhang, Xiaomei Ling, Ning Yu, Jing Li, Haisong yang, Runtao Li, Jingrong Cui, 2013
Interactions between N-terminal extracellular tail of CCR4 and natural products of licorice using capillary electrophoresis, Meina Li, Qing Wang, Xiaomei Ling, Lu Yang, Zhongjie Li, Min Ye, Ying Wang, 2013
N-terminal extracellular tail of CC chemokine receptor 4 (ML40) immobilized on capillary column to study the interactions between ML40 and its potential ligands, Wen-Jing Chen, Pazilaiti.Yakufu, Xiao-Mei Ling, Hui Qi, Jun-Hai Xiao, Ying Wang, 2012
Determination of 4-methylpiperaine-1-carbodithioc acid 3-cyano-3, 3-diphenylpropyl ester hydrochloride in Rats’ Plasma by Online-SPE-HPLC-DAD: Application to a Pharmacokinetic Study, Jianmei Zhang, Wensi Lin, Xiaona Li, Ning Yu, Xiaomei Ling, Ge Fu, Runtao Li, Jingrong Cui, 2012
Screening of thiourea derivatives and carbonyl-2-aminothiazole derivatives for potential CCR4 antagonists using capillary zone electrophoresis, Shuyu Zhang, Hui Qi, Pazilaiti. Yakufu, Fang Zhao, Xiaomei Ling, Junhai Xiao, Ying Wang, 2011
Qualitative and quantitative determination of oligonucleotide by non-gel capillary electrophoresis, Wujie Li, Yinling Ma, Zhu Gan, Xiaomei Ling, Zhenjun Yang, 2011
Studies on the adenosine deaminase-catalyzed conversion of adenosine and nucleoside prodrugs by different capillary electrophoresis modes, Lu Pei, Lujia Xie, Qian Lin, Xiaomei Ling, Zhu Guan, Zhenjun Yang, 2011
Screening of chemokine receptor CCR4 antagonists by capillary zone electrophoresis, Zhe Sun, Linjie Tian, Qian Lin, Xiaomei Ling, Haijun Xiao, Ying Wang, 2011
Simultaneous determination of 4-methyl-piperazine-1-carbodithioc acid 3-cyano-3,3-diphenylpropyl ester hydrochloride and its major metabolite in rats by high-performance liquid chromatography, Xiaomei Jing, Yihao Bai, Xiaomei Ling, Fangbin Han, Runtao Li, Jingrong Cui, 2010
Study on steady-state kinetics of nucleotide analogues incorporation by non-gel capillary electrophoresis, Wujie Li, Mou Cao, Lu Pei, Xiaomei Ling, Bingchao Li, Zhenjun Yang, 2010
Study on the interaction between HIV reverse transcriptase and its non-nucleoside inhibitor nevirapine by capillary electrophoresis, Wenjing Chen, Wujie Li, Xiaomei Ling, Xiaowei Wang, Junyi Liu, 2010
Gas-fragmentation study of the novel synthetic zwitterionic drug 3-methyl-9-(2-oxa-2λ5-2H-1,3,2-oxazaphosphorine-2-cyclohexyl)-3,6,9-triazaspiro[5,5]undecane chloride (SLXM-2) by electrospray ionization tandem mass spectrometry, Siting Wang, Yan Song, Jiao Wang, Xiaomei Ling, Zemei Ge, Runtao Li, Jingrong Cui, 2010
LC and LC–MS Study of the Bioavailability and Metabolites of TM208 after Oral and Intravenous Administration to Rat, Jiao Wang, Yan Song, Jianmei Zhang, Xiaona Li, Xiaomei Ling, Runtao Li, Jingrong Cui, 2010
Interactions Between Thrombin and Natural Products of Millettia nitita var. hirsutissima Using Capillary Zone Electrophoresis, Shuyu Zhang, Jun Cheng, Wenjing Chen, Xiaomei Ling, Yiying Zhao, Jie Feng, Cheng Xiang, Hong Liang, 2009
Determination of anti-tumor agent TM208, 4-methyl-piperazine-1-carbodithioc acid 3-cyano-3,3-diphenylpropyl ester hydrochloride, in rats by LC, Detao Kong, Siting Wang, Xiaomei Ling, Runtao Li, Jingrong Cui, 2009
Capillary electrophoresis for screening of 20S proteasome inhibitors, Wenjing Chen, Ke Mou, Bo Xu, Xiaomei Ling, Jingrong Cui, Ping Xu, 2009
Interactions of the peptides from secreted human CKLF1 and the N-terminal extracellular tail of CCR4 analyzed by capillary zone electrophoresis, Zhe Sun, Xiaomei Ling, Yingmei Zhang, Linjie Tian, Ying Wang, 2009
Advances of methods of protein immobilization on capillary, Wenjing Chen, Xiaomei Ling, 2009
Determination of Chloride 3-Methyl-9-(2-oxa-2k5-2H-1,3,2- Oxazaphosphorine-Cyclohexyl)-3,6,9- Triazaspiro [5.5] Undecane (SLXM-2) in Rats by LC:Application to a Pharmacokinetic Study, Yihao Bai, Zhen Chen, Xiaomei Ling, Runtao Li, Jingrong Cui, 2009
Keywords
Drug AnalysisBiomedical ApplicationsNew TechniquesNew MethodsBiomarkersDrug EfficacyDisease OccurrenceDisease DevelopmentDisease OutcomeMulti-Omics Research
Area of Focus
Drug Development | New Technologies | New Methods | Drug Targets | Biomarkers | Antiviral | Small Molecules | Protein Biopharmaceuticals | Discovery | Validation
Area of Focus
Protein Analysis | Dna Analysis | New Techniques | Biotechnology | Molecular Biology | Analytical Chemistry | Drug Analysis | Quality Control | Pharmaceuticals | Research
