Upload Avatar (500 x 500)
Liangyi Chen
Life Sciences / Medical / Biology
Peking University
Beijing
Language: Chinese, English
Diabetes
Insulin
Secretion
Biomedical Imaging
High Resolution
Spatiotemporal
Microscopy
Super-Resolution
Live-Cell Imaging
Fluorescence
Areas of Focus
- Mechanisms of insulin secretion abnormalities in diabetes
- High spatiotemporal resolution biomedical imaging techniques
Work Experience
- 2001.4-2004.6 Postdoctoral Researcher, Department of Physiology and Biophysics, University of Washington, supervised by Professor Bertil Hille
- 2004.6-2010.6 Associate Researcher, Institute of Biophysics, Chinese Academy of Sciences
- 2010.6-present Researcher, Institute of Molecular Medicine, Peking University
- 2020.1-present Boyuan Distinguished Professor, Institute of Molecular Medicine, Peking University
Academic Background & Achievements
- 1990.9-1992.7 Youth Class 01: Xi'an Jiaotong University
- 1992.9-1995.7 Bachelor's in Bioengineering and Medical Instruments: Xi'an Jiaotong University
- 1995.9-1998.7 Master's in Bioelectronics: Huazhong University of Science and Technology, supervised by Professors Huaguang Kang and Anlian Qu
- 1998.9-2001.4 Ph.D. in Biomedical Engineering: Huazhong University of Science and Technology, supervised by Professors Huaguang Kang and Shoubin Zou
- Recipient of National Science Fund for Distinguished Young Scholars and Excellent Young Scholars
Publications
- Sparse deconvolution improves the resolution of live-cell super-resolution fluorescence microscopy, Zhao W, Zhao S, Li L, Huang X, Xing S, Zhang Y, Qiu G, Han Z, Shang Y, Sun D, Shan C, Wu R, Gu L, Zhang S, Chen R, Xiao J, Mo Y, Wang J, Ji W, Chen X, Ding B, Liu Y, Mao H, Song B, Tan J, Liu J, Li H, Chen L, 2023
- Miniature two-photon microscopy for enlarged field-of-view, multi-plane and long-term brain imaging, Zong W, Wu R, Chen S, Wu J, Wang H, Zhao Z, Chen G, Tu R, Wu D, Hu Y, Xu Y, Wang Y, Duan Z, Wu H, Zhang Y, Wang A, Chen L, Cheng H, 2021
- Live-cell superresolution pathology reveals different molecular mechanisms of Pelizaeus-Merzbacher disease, Zheng X, Duan R, Li L, Xing S, Ji H, Yan H, Gao K, Wang J, Wang J, Chen L, 2020
- Super-resolution fluorescence-assisted diffraction computational tomography reveals the three-dimensional landscape of the cellular organelle interactome, Dong D, Huang X, Li L, Mao H, Mo Y, Zhang G, Zhang Z, Shen J, Liu W, Wu Z, Liu G, Liu Y, Yang H, Gong Q, Shi K, Chen L, 2020
- In Vivo imaging of β-cell function reveals glucose-mediated heterogeneity of β-cell functional development, Zhao J, Zong W, Zhao Y, Gou D, Liang S, Shen J, Wu Y, Zheng X, Wu R, Wang X, Niu F, Wang A, Zhang Y, Xiong JW, Chen L, Liu Y, 2019
- Fast, long-term super-resolution imaging with Hessian structured illumination microscopy, Huang X, Fan J, Li L, Liu H, Wu R, Wu Y, Wei L, Mao H, Lal A, Xi P, Tang L, Zhang Y, Liu Y, Tan S, Chen L, 2018
- Fast High-resolution Miniature Two-photon Microscopy for Brain Imaging in Freely-behaving Mice, Zong W, Wu R, Li M, Hu Y, Li Y, Li J, Rong H, Wu H, Xu Y, Lu Y, Jia H, Fan M, Zhou Z, Zhang Y, Wang A, Chen L, Cheng H, 2017
- Diacylglycerol Guides the Hopping of Clathrin-Coated Pits along Microtubules for Exo-Endocytosis Coupling, Yuan T, Liu L, Zhang Y, Wei L, Zhao S, Zheng X, Huang X, Boulanger J, Gueudry C, Lu J, Xie L, Du W, Zong W, Yang L, Salamero J, Liu Y, Chen L, 2015
- Large-field high-resolution two-photon digital scanned light-sheet microscopy, Zong W, Zhao J, Chen X, Lin Y, Ren H, Zhang Y, Fan M, Zhou Z, Cheng H, Sun Y, Chen L, 2015
Awards
- National Science Fund for Distinguished Young Scholars
- National Science Fund for Excellent Young Scholars
