Professor | Liangyi Chen | Asia Growth Partners

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Name	Liangyi Chen
Contact Information	lychen@pku.edu.cn
Language ability	Chinese, English
Province	Beijing

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Name

Liangyi Chen

Contact Information

lychen@pku.edu.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Life Sciences / Medical / Biology
Academic Background & Achievements	1990.9-1992.7 Youth Class 01: Xi'an Jiaotong University 1992.9-1995.7 Bachelor's in Bioengineering and Medical Instruments: Xi'an Jiaotong University 1995.9-1998.7 Master's in Bioelectronics: Huazhong University of Science and Technology, supervised by Professors Huaguang Kang and Anlian Qu 1998.9-2001.4 Ph.D. in Biomedical Engineering: Huazhong University of Science and Technology, supervised by Professors Huaguang Kang and Shoubin Zou Recipient of National Science Fund for Distinguished Young Scholars and Excellent Young Scholars
Work Experience	2001.4-2004.6 Postdoctoral Researcher, Department of Physiology and Biophysics, University of Washington, supervised by Professor Bertil Hille 2004.6-2010.6 Associate Researcher, Institute of Biophysics, Chinese Academy of Sciences 2010.6-present Researcher, Institute of Molecular Medicine, Peking University 2020.1-present Boyuan Distinguished Professor, Institute of Molecular Medicine, Peking University
Awards	National Science Fund for Distinguished Young Scholars National Science Fund for Excellent Young Scholars

University/Lab Affiliation and Title

Peking University

Faculty

Life Sciences / Medical / Biology

Academic Background & Achievements

1990.9-1992.7 Youth Class 01: Xi'an Jiaotong University
1992.9-1995.7 Bachelor's in Bioengineering and Medical Instruments: Xi'an Jiaotong University
1995.9-1998.7 Master's in Bioelectronics: Huazhong University of Science and Technology, supervised by Professors Huaguang Kang and Anlian Qu
1998.9-2001.4 Ph.D. in Biomedical Engineering: Huazhong University of Science and Technology, supervised by Professors Huaguang Kang and Shoubin Zou
Recipient of National Science Fund for Distinguished Young Scholars and Excellent Young Scholars

Work Experience

2001.4-2004.6 Postdoctoral Researcher, Department of Physiology and Biophysics, University of Washington, supervised by Professor Bertil Hille
2004.6-2010.6 Associate Researcher, Institute of Biophysics, Chinese Academy of Sciences
2010.6-present Researcher, Institute of Molecular Medicine, Peking University
2020.1-present Boyuan Distinguished Professor, Institute of Molecular Medicine, Peking University

Awards

National Science Fund for Distinguished Young Scholars
National Science Fund for Excellent Young Scholars

Areas of Focus	Mechanisms of insulin secretion abnormalities in diabetes High spatiotemporal resolution biomedical imaging techniques
Publications	Sparse deconvolution improves the resolution of live-cell super-resolution fluorescence microscopy, Zhao W, Zhao S, Li L, Huang X, Xing S, Zhang Y, Qiu G, Han Z, Shang Y, Sun D, Shan C, Wu R, Gu L, Zhang S, Chen R, Xiao J, Mo Y, Wang J, Ji W, Chen X, Ding B, Liu Y, Mao H, Song B, Tan J, Liu J, Li H, Chen L, 2023 Miniature two-photon microscopy for enlarged field-of-view, multi-plane and long-term brain imaging, Zong W, Wu R, Chen S, Wu J, Wang H, Zhao Z, Chen G, Tu R, Wu D, Hu Y, Xu Y, Wang Y, Duan Z, Wu H, Zhang Y, Wang A, Chen L, Cheng H, 2021 Live-cell superresolution pathology reveals different molecular mechanisms of Pelizaeus-Merzbacher disease, Zheng X, Duan R, Li L, Xing S, Ji H, Yan H, Gao K, Wang J, Wang J, Chen L, 2020 Super-resolution fluorescence-assisted diffraction computational tomography reveals the three-dimensional landscape of the cellular organelle interactome, Dong D, Huang X, Li L, Mao H, Mo Y, Zhang G, Zhang Z, Shen J, Liu W, Wu Z, Liu G, Liu Y, Yang H, Gong Q, Shi K, Chen L, 2020 In Vivo imaging of β-cell function reveals glucose-mediated heterogeneity of β-cell functional development, Zhao J, Zong W, Zhao Y, Gou D, Liang S, Shen J, Wu Y, Zheng X, Wu R, Wang X, Niu F, Wang A, Zhang Y, Xiong JW, Chen L, Liu Y, 2019 Fast, long-term super-resolution imaging with Hessian structured illumination microscopy, Huang X, Fan J, Li L, Liu H, Wu R, Wu Y, Wei L, Mao H, Lal A, Xi P, Tang L, Zhang Y, Liu Y, Tan S, Chen L, 2018 Fast High-resolution Miniature Two-photon Microscopy for Brain Imaging in Freely-behaving Mice, Zong W, Wu R, Li M, Hu Y, Li Y, Li J, Rong H, Wu H, Xu Y, Lu Y, Jia H, Fan M, Zhou Z, Zhang Y, Wang A, Chen L, Cheng H, 2017 Diacylglycerol Guides the Hopping of Clathrin-Coated Pits along Microtubules for Exo-Endocytosis Coupling, Yuan T, Liu L, Zhang Y, Wei L, Zhao S, Zheng X, Huang X, Boulanger J, Gueudry C, Lu J, Xie L, Du W, Zong W, Yang L, Salamero J, Liu Y, Chen L, 2015 Large-field high-resolution two-photon digital scanned light-sheet microscopy, Zong W, Zhao J, Chen X, Lin Y, Ren H, Zhang Y, Fan M, Zhou Z, Cheng H, Sun Y, Chen L, 2015

Areas of Focus

Mechanisms of insulin secretion abnormalities in diabetes
High spatiotemporal resolution biomedical imaging techniques

Publications

Sparse deconvolution improves the resolution of live-cell super-resolution fluorescence microscopy, Zhao W, Zhao S, Li L, Huang X, Xing S, Zhang Y, Qiu G, Han Z, Shang Y, Sun D, Shan C, Wu R, Gu L, Zhang S, Chen R, Xiao J, Mo Y, Wang J, Ji W, Chen X, Ding B, Liu Y, Mao H, Song B, Tan J, Liu J, Li H, Chen L, 2023
Miniature two-photon microscopy for enlarged field-of-view, multi-plane and long-term brain imaging, Zong W, Wu R, Chen S, Wu J, Wang H, Zhao Z, Chen G, Tu R, Wu D, Hu Y, Xu Y, Wang Y, Duan Z, Wu H, Zhang Y, Wang A, Chen L, Cheng H, 2021
Live-cell superresolution pathology reveals different molecular mechanisms of Pelizaeus-Merzbacher disease, Zheng X, Duan R, Li L, Xing S, Ji H, Yan H, Gao K, Wang J, Wang J, Chen L, 2020
Super-resolution fluorescence-assisted diffraction computational tomography reveals the three-dimensional landscape of the cellular organelle interactome, Dong D, Huang X, Li L, Mao H, Mo Y, Zhang G, Zhang Z, Shen J, Liu W, Wu Z, Liu G, Liu Y, Yang H, Gong Q, Shi K, Chen L, 2020
In Vivo imaging of β-cell function reveals glucose-mediated heterogeneity of β-cell functional development, Zhao J, Zong W, Zhao Y, Gou D, Liang S, Shen J, Wu Y, Zheng X, Wu R, Wang X, Niu F, Wang A, Zhang Y, Xiong JW, Chen L, Liu Y, 2019
Fast, long-term super-resolution imaging with Hessian structured illumination microscopy, Huang X, Fan J, Li L, Liu H, Wu R, Wu Y, Wei L, Mao H, Lal A, Xi P, Tang L, Zhang Y, Liu Y, Tan S, Chen L, 2018
Fast High-resolution Miniature Two-photon Microscopy for Brain Imaging in Freely-behaving Mice, Zong W, Wu R, Li M, Hu Y, Li Y, Li J, Rong H, Wu H, Xu Y, Lu Y, Jia H, Fan M, Zhou Z, Zhang Y, Wang A, Chen L, Cheng H, 2017
Diacylglycerol Guides the Hopping of Clathrin-Coated Pits along Microtubules for Exo-Endocytosis Coupling, Yuan T, Liu L, Zhang Y, Wei L, Zhao S, Zheng X, Huang X, Boulanger J, Gueudry C, Lu J, Xie L, Du W, Zong W, Yang L, Salamero J, Liu Y, Chen L, 2015
Large-field high-resolution two-photon digital scanned light-sheet microscopy, Zong W, Zhao J, Chen X, Lin Y, Ren H, Zhang Y, Fan M, Zhou Z, Cheng H, Sun Y, Chen L, 2015

Diabetes Insulin Secretion Biomedical Imaging High Resolution Spatiotemporal Microscopy Super-Resolution Live-Cell Imaging Fluorescence

Peng Xi - Peking University

Hanqing Xiong - Peking University

Yujie Sun - Peking University

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