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Zhixing Chen
Life Sciences / Medical / Biology
Peking University
Beijing
Language: Chinese, English
Imaging Probes
Labeling Techniques
Small Molecules
Polymers
Biomacromolecules
Organic Synthesis
Spectroscopy
Chemical Biology
Bioimaging
Molecular Engineering
Areas of Focus
- Development of imaging probes and labeling techniques based on small molecules, polymers, and biomacromolecules
Work Experience
- 2008.7-2009.8 - Peking University - Research Assistant
- 2015.3-2015.12 - Columbia University - Postdoctoral Researcher
- 2016.1-2018.3 - Stanford University - Postdoctoral Researcher
- 2018.6-present - Peking University - Researcher at the School of Future Technology, Joint Center for Life Sciences
Academic Background & Achievements
- 2004-2008 Bachelor of Science: Tsinghua University
- 2009-2014 Ph.D.: Columbia University, Supervisors: Profs. Virginia W. Cornish & Wei Min
Publications
- General Strategy To Improve the Photon Budget of Thiol-Conjugated Cyanine Dyes, Zhang, Y.; Yang, C.; Peng, S.; Ling, J.; Chen, P.; Ma, Y.; Wang, W.; Chen, Z.; Chen, C., 2023
- Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain, Liu, T.; Stephen, T.; Chen, P.; Keller-Findeisen, J.; Chen, J.; Riedel, D.; Yang, Z.; Jakobs, S.; Chen, Z., 2022
- Third-Generation Covalent TMP-Tag for Fast Labeling and Multiplexed Imaging of Cellular Proteins, Mo, J.; Chen, J.; Shi, Y.; Sun, J.; Wu, Y.; Liu, T.; Zhang, J.; Zheng, Y.; Li, Y.; Chen, Z., 2022
- Emerging trends in fluorescence bioimaging of divalent metal cations using small-molecule indicators, Liu, M.; Zhang, J.; Chen, Z., 2022
- Red- and Far-Red-Emitting Zinc Probes with Minimal Phototoxicity for Multiplexed Recording of Orchestrated Insulin Secretion, Zhang, J.; Peng, X.; Wu, Y.; Ren, H.; Sun, J.; Tong, S.; Liu, T.; Zhao, Y.; Wang, S.; Tang, C.; Chen, L.; Chen, Z., 2021
- Cyclooctatetraene-conjugated cyanine mitochondrial probes minimize phototoxicity in fluorescence and nanoscopic imaging, Yang, Z.; Li, L.; Ling, J.; Liu, T.; Huang, X.; Ying, Y.; Zhao, Y.; Zhao, Y.; Lei, K.; Chen, L.; Chen, Z., 2020
- The cascade unzipping of ladderane reveals dynamic effects in mechanochemistry, Chen, Z.; Zhu, X.; Yang, J.; Mercer, J. A. M.; Burns, N. Z.; Martinez, T. J.; Xia, Y., 2020
- Mechanochemical unzipping of insulating polyladderene to semiconducting polyacetylene, Chen, Z.; Mercer, J. A. M.; Zhu, X.; Romaniuk, J. A. H.; Pfattner, R.; Cegelski, L.; Martinez, T. J.; Burns, N. Z.; Xia, Y., 2017
- Super-multiplex vibrational imaging, Wei, L.; Chen, Z.; Shi, L.; Long, R.; Anzalone, A. V.; Zhang, L.; Hu, F.; Yuste, R.; Cornish, V. W.; Min, W., 2017
- Multicolor Live-Cell Chemical Imaging by Isotopically Edited Alkyne Vibrational Palette, Chen, Z.; Paley, D. W.; Wei, L.; Weisman, A. L.; Friesner, R. A.; Nuckolls, C.; Min, W., 2014
- Chemical Tags: Inspiration for Advanced Imaging Techniques, Chen, Z.; Cornish, V. W.; Min, W., 2013
- Mapping Protein-Specific Micro-Environments in Live Cells by Fluorescence Lifetime Imaging of a Hybrid Genetic-Chemical Molecular Rotor Tag, Gatzogiannis, E.; Chen, Z.; Wei, L.; Wombacher, R.; Kao, Y.-T.; Yefremov, G.; Cornish, V. W.; Min, W., 2012
- Second-Generation Covalent TMP-Tag for Live Cell Imaging, Chen, Z.; Jing, C.; Gallagher, S. S.; Sheetz, M. P.; Cornish, V. W., 2012
- Extending the Fundamental Imaging-Depth Limit of Multi-Photon Microscopy by Imaging with Photo-Activatable Fluorophores, Chen, Z.; Wei, L.; Zhu, X.; Min, W., 2012
- Diastereoselective Total Synthesis of (±)-Schindilactone A, Xiao, Q.; Ren, W.-W.; Chen, Z.-X.; Sun, T.-W.; Li, Y.; Ye, Q.-D.; Gong, J.-X.; Meng, F.-K.; You, L.; Liu, Y.-F.; Zhao, M.-Z.; Xu, L.-M.; Shan, Z.-H.; Shi, Y.; Tang, Y.-F.; Chen, J.-H.; Yang, Z., 2011
