Areas of Focus
- Cellular stress and homeostasis regulation
- Mitochondrial stress response
- Amino acid deprivation response
- Cancer
- Metabolic diseases
- Aging
Work Experience
- 2011.8 – 2014.2 - Massachusetts General Hospital, Harvard Medical School - Postdoctoral Researcher
- 2013.12 – 2019.8 - Peking University Institute of Molecular Medicine - Researcher
- 2019.8 – 2021.2 - Peking University Institute of Molecular Medicine - Deputy Director, Associate Professor with tenure
- 2021.2 – Present - Peking University School of Future Technology - Vice Dean, Professor
Academic Background & Achievements
- 2002-2006 Bachelor: Nanjing University, Biotechnology
- 2006-2011 PhD: University of Texas Southwestern Medical Center, Biochemistry
- HHMI International Research Scholar
- National Science Fund for Distinguished Young Scholars
- Science Exploration Award
- China Young Female Scientist Award
Publications
- E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression, Wang D, Xu C, Yang W, Chen J, Ou Y, Guan Y, Guan J, Liu Y, 2022
- Splicing factor PRP-19 regulates mitochondrial stress response, Xia P, Zhou L, Guan J, Ding W, Liu Y, 2022
- SAR1B senses leucine levels to regulate mTORC1 signalling, Chen J, Ou Y, Luo R, Wang J, Wang D, Guan J, Li Y, Xia P, Chen P, Liu Y, 2021
- HLH-11 modulates lipid metabolism in response to nutrient availability, Li Y, Ding W, Li C-Y, Liu Y, 2020
- Epigenetic codes of mitochondrial homeostasis, Liu Y, 2021
- Histone deacetylase HDA-1 modulates mitochondrial stress response and longevity, Shao L-W, Peng Q, Dong M, Gao K, Li YM, Li Y, Li C-Y, Liu Y, 2020
- SUMO peptidase ULP-4 regulates mitochondrial UPR-mediated innate immunity and lifespan extension, Gao K, Li Y, Hu SM, Liu Y, 2019
- N6-methyldeoxyadenine is a transgenerational epigenetic signal for mitochondrial stress adaptation, Ma C, Niu R, Huang T, Shao LW, Peng Y, Ding W, Wang Y, Jia G, He C, Li CY, He A, Liu Y, 2019
- KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing, Chen J, Ou Y, Li Y, Hu S, Shao LW, Liu Y, 2018
- Metformin extends C. elegans lifespan through lysosomal pathway, Chen J, Ou Y, Li Y, Hu S, Shao LW, Liu Y, 2017
- Neuropeptide signals cell non-autonomous mitochondrial unfolded protein response, Shao LW, Niu R, Liu Y, 2016
- Caenorhabditis elegans pathways that surveil and defend mitochondria, Liu Y, Samuel BS, Breen PC, Ruvkun G, 2014
- Autoantigen La promotes efficient RNAi, antiviral response and transposon silencing by facilitating multiple-turnover RISC catalysis, Liu Y, Tan H, Tian H, Liang C, Chen S, Liu Q, 2011
- C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation, Liu Y, Ye X, Jiang F, Liang C, Chen D, Peng J, Kinch L, Grishin N, Liu Q, 2009
Awards
- HHMI International Research Scholar: Detail not mentioned
- National Science Fund for Distinguished Young Scholars: Detail not mentioned
- Science Exploration Award: Detail not mentioned
- China Young Female Scientist Award: Detail not mentioned