1994-1997 Doctor of Medicine: Chinese Academy of Medical Sciences & Peking Union Medical College
1991-1994 Master of Medicine: China Medical University
1986-1991 Bachelor of Medicine: China Medical University
2015 Shanghai Medical Leading Talent
2016 Shanghai Leading Talent
2007.12-present - Fudan University, Institute of Biomedical Sciences - Researcher
2021-present - Zhongshan Hospital affiliated to Fudan University - Joint Professor
2007-present - Shanghai Public Health Clinical Center, Institute of Translational Medicine - Joint Professor, Dean
2004-2007 - National Center for AIDS/STD Control and Prevention, China CDC - Associate Researcher
2001-2004 - Georgetown University, Department of Microbiology and Immunology - Research Assistant Professor
2001-2004 - Research Institute for Genetic and Human Therapy affiliated to Georgetown University - Senior Research Associate
1997-2001 - Research Institute for Genetic and Human Therapy affiliated to Georgetown University - Postdoctoral Research Fellow
2004-2006 Advanced Worker at National Center for AIDS/STD Control and Prevention, China CDC (three consecutive years)
2008 Outstanding Discipline Leader in Public Health, Shanghai
2009 Excellent Undergraduate Course Lecturer at Shanghai Public Health Clinical Center
2010 Academic Advisor at Nankai University AIDS Research Center
2011 Third Prize of Shanghai Medical Science and Technology Award (second contributor)
2011 Excellent Academic Leader in Shanghai
2011 Training Object of the New Round of Excellent Discipline Leader Training Program in Shanghai Health System
2011 Bronze Award of Excellent Team and Talent Reward Program at Shanghai Public Health Clinical Center
2012 Distinguished Expert of Science and Technology Innovation Team in Infection and Immunity at Heilongjiang Universities
2013 Third Prize of Shanghai Science and Technology Award (third contributor)
Research
Research on immune protection and pathogenic mechanisms of infections Development of immunotherapy, drugs, and vaccines against infections Development of new tumor immunotherapy technologies
High expression of oleoyl-ACP-hydrolase underpins life-threatening respiratory viral diseases., Jia X, Crawford JC, Gebregzabher D, Monson EA, Mettelman RC, Wan Y, Ren Y, Chou J, Novak T, McQuilten HA, Clarke M, Bachem A, Foo IJ, Fritzlar S, Montoya JC, Trenerry AM, Nie S, Leeming MG, Nguyen THO, Kedzierski L, Littler D, Kueh A, Cardamone T, Wong C, Hensen L, Cabug A1, Gómez Laguna J, Agrawal M, Flerlage T, Boyd DF, Van de Velde LE, Habel JR, Loh L, Koay HF, van de Sandt C, Konstantinov IE, Berzins SP, Flanagan KL, Wakim LM, Herold MJ, Green AM, Smallwood HS, Rossjohn J, Thwaites RS, Chiu C, Scott NE, Mackenzie JM, Bedoui S, Reading PC, Londrigan SL, Helbig KJ, Randolph AG, Thomas PG, Xu J, Wang Z, Chua and Kedzierska K., 2024
Efficacy and safety of novel multifunctional M10 CAR-T cells in HIV-1-infected patients: a phase I, multicenter, single-arm, open-label study., Mao Y, Liao Q, Zhu Y, Bi M, Zou J, Zheng N, Zhu L, Zhao C, Liu Q, Liu L, Chen J, Gu L, Liu Z, Pan X, Xue Y, Feng M, Ying T, Zhou P, Wu Z, Xiao J, Zhang R, Leng J, Sun Y, Zhang X, Xu J., 2024
One HA stalk topping multiple heads as a novel influenza vaccine., Zhou P, Qiu T, Wang X, Yang X, Shi H, Zhu C, Dai W, Xing M, Zhang X, Xu J, Zhou D., 2024
An intranasal combination vaccine induces systemic and mucosal immunity against COVID-19 and influenza., Xing M, Hu G, Wang X, Wang Y, He F, Dai W, Wang X, Niu Y, Liu J, Liu H, Zhang X, Xu J, Cai Q, Zhou D., 2024
Reduced clinical severity during 2022 Shanghai Spring epidemic of SARS-CoV-2 omicron BA.2 variant infection - An integrated account of virus pathogenicity and vaccination effectiveness., Xingyue Wu, Yao Chen, Kangli Cao, Yao Shen, Xueling Wu, Yilin Yang, Zhongshu Kuang, Qingrun Li, Zhenzhen Lu, Yichen Jia, Mian Shao, Guorong Gu, Xiangwei Wang, Ye Yao, Ying Wang, Shaodie Chen, Zhigao Yu, Wei Wei, Longfei Ding, Lulu Lan, Tianwen Gu, Xiangyu Long, Jian Sun, Lingyu Xing, Jiayuan Shen, Yi Han, Yue Luo, Sucheng Mu, Mengna Lin, Xiaoyan Zhang, Rong Zeng, Jianqing Xu, Guoping Zhao, Lihong Huang, Zhenju Song., 2024
One HA stalk topping multiple heads as a novel influenza vaccine., Zhou P, Qiu T, Wang X, Yang X, Shi H, Zhu C, Dai W, Xing M, Zhang X, Xu J, Zhou D., 2023
CD160 Signaling Is Essential for CD8+ T Cell Memory Formation via Upregulation of 4-1BB., Zhang L, Zhang A, Zhu X, Tian X, Guo J, He Q, Zhu L, Yuan S, Zhao C, Zhang X, Xu J., 2023
Induced regulatory T cells modified by knocking down T-bet in combination with ectopic expression of inhibitory cytokines effectively protect graft-versus-host disease., Gao R, Li A, Li S, Li X, Zhang S, Zhang X, Xu J., 2023
Rapid generation of a mouse model for evaluating on-target normal tissue toxicity of human CAR-T cells using replication-defective recombinant adenovirus., Qibin Liao, Huan He, Zhuoqun Liu, Cuisong Zhu, Meiqi Feng, Lang Jiang, Xiangqing Ding, Xiaoyan Zhang, Jianqing Xu., 2023
A follow-up study on the recovery and reinfection of Omicron COVID-19 patients in Shanghai, China., Lin M, Cao K, Xu F, Wu X, Shen Y, Lu S, Kuang Z, Ding H, Yuan S, Shao M, Gu G, Xing L, Gu T, Chen S, Sun J, Zhu J, Zhang X, Yang Y, Zhao G, Huang L, Xu J, Song Z., 2023
Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2., Xiaoyu Sun, Chunyan Yi, Yuanfei Zhu, Longfei Ding, Shuai Xia, Xingchen Chen, Mu Liu, Chenjian Gu, Xiao Lu, Yadong Fu, Shuangfeng Chen, Tianlong Zhang, Yaguang Zhang, Zhuo Yang, Liyan Ma, Wangpeng Gu, Gaowei Hu, Shujuan Du, Renhong Yan, Weihui Fu, Songhua Yuan, Chenli Qiu, Chen Zhao, Xiaoyan Zhang, Yonghui He, Aidong Qu, Xu Zhou, Xiuling Li, Gary Wong, Qiang Deng, Qiang Zhou, Hongzhou Lu, Zhiyang Ling, Jianping Ding, Lu Lu, Xu J, Youhua Xie, Bing Sun., 2022
The kinase complex mTORC2 promotes the longevity of virus-specific memory CD4+ T cells by preventing ferroptosis., Wang Y, Tian Q, Hao Y, Yao W, Lu J, Chen C, Chen X, Lin Y, Huang Q, Xu L, Hu J, Lei S, Wei Z, Luo Y, Li Z, Hu L, Tang J, Wu Q, Zhou X, Wu Y, Yin Z, Xu J, Ye L., 2022
Feasibility of iNKT cell and PD-1+CD8+ T cell-based immunotherapy in patients with lung adenocarcinoma: Preliminary results of a phase I/II clinical trial., Cheng X, Wang J, Qiu C, Jin Y, Xia B, Qin R, Hu H, Yan J, Zhang X, Xu J., 2022
A Single Vaccine Protects against SARS-CoV-2 and Influenza Virus in Mice., Cao K, Wang X, Peng H, Ding L, Wang X, Hu Y, Dong L, Yang T, Hong X, Xing M, Li D, Zhu C, He X, Zhao C, Zhao P, Zhou D, Zhang X, Xu J., 2022
SARS-CoV-2 RNA elements share human sequence identity and upregulate hyaluronan via NamiRNA-enhancer network., Li W, Yang S, Xu P, Zhang D, Tong Y, Chen L, Jia B, Li A, Lian C, Ru D, Zhang B, Liu M, Chen C, Fu W, Yuan S, Gu C, Wang L, Li W, Liang Y, Yang Z, Ren X, Wang S, Zhang X, Song Y, Xie Y, Lu H, Xu J, Wang H, Yu W., 2022
Pathologically complete remission to combination of invariant NK T cells and anti-CD