Professor | Aijun Sun | Asia Growth Partners

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Name	Aijun Sun
Contact Information	sun.aijun@zs-hospital.sh.cn
Language ability	English, Chinese, German
Province	Shanghai

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Name

Aijun Sun

Contact Information

sun.aijun@zs-hospital.sh.cn

Language ability

English, Chinese, German

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Biomedical Sciences
Academic Background & Achievements	1999-2002 PhD: Shanghai Jiao Tong University, Cardiology 1996-1999 Master's: Soochow University, Cardiology New Century Excellent Talents, Ministry of Education, 2012 Shuguang Scholar, Shanghai Municipal Education Commission, 2009 Rising Star Follow-up Program, Shanghai Science and Technology Commission, 2009 Rising Star Program, Shanghai Science and Technology Commission, 2006
Work Experience	2015.05-present - Texas A&M University, Health Science Center - Adjunct Professor 2014.08-2015.07 - Texas Medical Center, School of Medicine - Visiting Scholar 2012.12-present - Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases - Doctoral Supervisor 2011.10-present - Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases - Researcher 2009.05-present - Fudan University, Institute of Biomedical Sciences - Dual-appointed PI 2005.05-2011.10 - Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases - Associate Researcher 2003.03-2004.05 - University of Essen, School of Medicine - Visiting Scholar 2002.08-2005.04 - Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases - Assistant Researcher
Awards	Science and Technology Progress Award Promotion Category Second Prize (Third Contributor), Ministry of Education, 2011 Science and Technology Award First Prize (Second Contributor), Shanghai Municipal Government, 2009 Science and Technology Progress Award First Prize (Second Contributor), Ministry of Education, 2009 Science and Technology Progress Award Second Prize (Third Contributor), Ministry of Education, 2008 Science and Technology Award Second Prize (Second Contributor), Chinese Medical Association, 2006 Wuzhou Women's Science and Technology Award (Basic Medical Research Innovation Award), Chinese Women Doctors Association, 2015 National Excellent Science and Technology Worker, China Association for Science and Technology, 2014 Silver Snake Award in Shanghai Health System, Shanghai Municipal Health and Family Planning Commission, 2011 Top Ten Young Science and Technology Talents in Shanghai (Fifth Session), Shanghai Association for Science and Technology, 2010

University/Lab Affiliation and Title

Fudan University

Faculty

Biomedical Sciences

Academic Background & Achievements

1999-2002 PhD: Shanghai Jiao Tong University, Cardiology
1996-1999 Master's: Soochow University, Cardiology
New Century Excellent Talents, Ministry of Education, 2012
Shuguang Scholar, Shanghai Municipal Education Commission, 2009
Rising Star Follow-up Program, Shanghai Science and Technology Commission, 2009
Rising Star Program, Shanghai Science and Technology Commission, 2006

Work Experience

2015.05-present - Texas A&M University, Health Science Center - Adjunct Professor
2014.08-2015.07 - Texas Medical Center, School of Medicine - Visiting Scholar
2012.12-present - Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases - Doctoral Supervisor
2011.10-present - Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases - Researcher
2009.05-present - Fudan University, Institute of Biomedical Sciences - Dual-appointed PI
2005.05-2011.10 - Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases - Associate Researcher
2003.03-2004.05 - University of Essen, School of Medicine - Visiting Scholar
2002.08-2005.04 - Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Diseases - Assistant Researcher

Awards

Science and Technology Progress Award Promotion Category Second Prize (Third Contributor), Ministry of Education, 2011
Science and Technology Award First Prize (Second Contributor), Shanghai Municipal Government, 2009
Science and Technology Progress Award First Prize (Second Contributor), Ministry of Education, 2009
Science and Technology Progress Award Second Prize (Third Contributor), Ministry of Education, 2008
Science and Technology Award Second Prize (Second Contributor), Chinese Medical Association, 2006
Wuzhou Women's Science and Technology Award (Basic Medical Research Innovation Award), Chinese Women Doctors Association, 2015
National Excellent Science and Technology Worker, China Association for Science and Technology, 2014
Silver Snake Award in Shanghai Health System, Shanghai Municipal Health and Family Planning Commission, 2011
Top Ten Young Science and Technology Talents in Shanghai (Fifth Session), Shanghai Association for Science and Technology, 2010

Areas of Focus	Mechanisms and translational research of heart failure Mitochondrial metabolism and myocardial protection Stem cell transplantation and energy metabolism
Publications	The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction, Yang, G., X. Weng, Y. Zhao, X. Zhang, Y. Hu, X. Dai, P. Liang, P. Wang, L. Ma, X. Sun, L. Hou, H. Xu, M. Fang, Y. Li, T. Jenuwein, Y. Xu, and A. Sun, 2017 Naoxintong attenuates Ischaemia/reperfusion Injury through inhibiting NLRP3 inflammasome activation, Wang, Y., X. Yan, S. Mi, Z. Li, Y. Wang, H. Zhu, X. Sun, B. Zhao, C. Zhao, Y. Zou, K. Hu, X. Ding, A. Sun, and J. Ge, 2017 Aldehyde dehydrogenase 2 deficiency negates chronic low-to-moderate alcohol consumption-induced cardioprotecion possibly via ROS-dependent apoptosis and RIP1/RIP3/MLKL-mediated necroptosis, Shen, C., C. Wang, S. Han, Z. Wang, Z. Dong, X. Zhao, P. Wang, H. Zhu, X. Sun, X. Ma, H. Zhu, Y. Zou, K. Hu, J. Ge, and A. Sun, 2016 Aldehyde Dehydrogenase-2 Roles in Ischemic Cardiovascular Disease, Liu, X., and A. Sun, 2016 Mitochondrial aldehyde dehydrogenase 2 deficiency aggravates energy metabolism disturbance and diastolic dysfunction in diabetic mice, Wang, C., F. Fan, Q. Cao, C. Shen, H. Zhu, P. Wang, X. Zhao, X. Sun, Z. Dong, X. Ma, X. Liu, S. Han, C. Wu, Y. Zou, K. Hu, J. Ge, and A. Sun, 2016 Aldehyde dehydrogenase 2 deficiency blunts compensatory cardiac hypertrophy through modulating Akt phosphorylation early after transverse aorta constriction in mice, Xia, G., F. Fan, M. Liu, S. Wang, J. Wu, C. Shen, S. Han, C. Wang, J. Jia, Y. Zou, K. Hu, J. Ge, and A. Sun, 2016 Energy Remodeling, Mitochondrial Disorder and Heart Failure, Wang, P., L. Xu, and A. Sun, 2016 SPECT imaging of cytochrome c in pressure overload mice hearts, Wang, C., X. Li, C. Shen, L.L. Ma, Z. Dong, H. Zhu, P. Wang, J.B. Ge, and A. Sun, 2016 Trans-Fatty Acids Aggravate Obesity, Insulin Resistance and Hepatic Steatosis in C57BL/6 Mice, Possibly by Suppressing the IRS1 Dependent Pathway, Zhao, X., C. Shen, H. Zhu, C. Wang, X. Liu, X. Sun, S. Han, P. Wang, Z. Dong, X. Ma, K. Hu, A. Sun, and J. Ge, 2016 Mitochondrial Aldehyde Dehydrogenase 2 Regulates Revascularization in Chronic Ischemia: Potential Impact on the Development of Coronary Collateral Circulation, Liu, X., X. Sun, H. Liao, Z. Dong, J. Zhao, H. Zhu, P. Wang, L. Shen, L. Xu, X. Ma, C. Shen, F. Fan, C. Wang, K. Hu, Y. Zou, J. Ge, J. Ren, and A. Sun, 2015 Acetaldehyde dehydrogenase 2 (ALDH2) deficiency exacerbates pressure overload-induced cardiac dysfunction by inhibiting Beclin-1 dependent autophagy pathway, Shen, C., C. Wang, F. Fan, Z. Yang, Q. Cao, X. Liu, X. Sun, X. Zhao, P. Wang, X. Ma, H. Zhu, Z. Dong, Y. Zou, K. Hu, A. Sun, and J. Ge, 2015 Aberrant hypermethylation of aldehyde dehydrogenase 2 promoter upstream sequence in rats with experimental myocardial infarction, Wang, P., C. Shen, L. Diao, Z. Yang, F. Fan, C. Wang, X. Liu, X. Sun, Z. Dong, H. Zhu, X. Ma, Q. Cao, X. Zhao, D. Ma, Y. Zou, K. Hu, A. Sun, and J. Ge, 2015 Aldehyde dehydrogenase-2 is a host factor required for effective bone marrow mesenchymal stem cell therapy, Zhu, H., A. Sun, H. Zhu, Z. Li, Z. Huang, S. Zhang, X. Ma, Y. Zou, K. Hu, and J. Ge, 2014 Aldehyde dehydrogenase 2 ameliorates doxorubicin-induced myocardial dysfunction through detoxification of 4-HNE and suppression of autophagy, Sun, A., Y. Cheng, Y. Zhang, Q. Zhang, S. Wang, S. Tian, Y. Zou, K. Hu, J. Ren, and J. Ge, 2014 Mitochondrial aldehyde dehydrogenase 2 plays protective roles in heart failure after myocardial infarction via suppression of the cytosolic JNK/p53 pathway in mice, Sun, A., Y. Zou, P. Wang, D. Xu, H. Gong, S. Wang, Y. Qin, P. Zhang, Y. Chen, M. Harada, T. Isse, T. Kawamoto, H. Fan, P. Yang, H. Akazawa, T. Nagai, H. Takano, P. Ping, I. Komuro*, and J

Areas of Focus

Mechanisms and translational research of heart failure
Mitochondrial metabolism and myocardial protection
Stem cell transplantation and energy metabolism

Publications

The histone H3K9 methyltransferase SUV39H links SIRT1 repression to myocardial infarction, Yang, G., X. Weng, Y. Zhao, X. Zhang, Y. Hu, X. Dai, P. Liang, P. Wang, L. Ma, X. Sun, L. Hou, H. Xu, M. Fang, Y. Li, T. Jenuwein, Y. Xu*, and A. Sun*, 2017
Naoxintong attenuates Ischaemia/reperfusion Injury through inhibiting NLRP3 inflammasome activation, Wang, Y., X. Yan, S. Mi, Z. Li, Y. Wang, H. Zhu, X. Sun, B. Zhao, C. Zhao, Y. Zou, K. Hu, X. Ding*, A. Sun*, and J. Ge*, 2017
Aldehyde dehydrogenase 2 deficiency negates chronic low-to-moderate alcohol consumption-induced cardioprotecion possibly via ROS-dependent apoptosis and RIP1/RIP3/MLKL-mediated necroptosis, Shen, C., C. Wang, S. Han, Z. Wang, Z. Dong, X. Zhao, P. Wang, H. Zhu, X. Sun, X. Ma, H. Zhu*, Y. Zou, K. Hu, J. Ge*, and A. Sun*, 2016
Aldehyde Dehydrogenase-2 Roles in Ischemic Cardiovascular Disease, Liu, X., and A. Sun*, 2016
Mitochondrial aldehyde dehydrogenase 2 deficiency aggravates energy metabolism disturbance and diastolic dysfunction in diabetic mice, Wang, C., F. Fan, Q. Cao, C. Shen, H. Zhu, P. Wang, X. Zhao, X. Sun, Z. Dong, X. Ma, X. Liu, S. Han, C. Wu, Y. Zou, K. Hu, J. Ge*, and A. Sun*, 2016
Aldehyde dehydrogenase 2 deficiency blunts compensatory cardiac hypertrophy through modulating Akt phosphorylation early after transverse aorta constriction in mice, Xia, G., F. Fan, M. Liu, S. Wang, J. Wu, C. Shen, S. Han, C. Wang, J. Jia, Y. Zou, K. Hu, J. Ge*, and A. Sun*, 2016
Energy Remodeling, Mitochondrial Disorder and Heart Failure, Wang, P., L. Xu, and A. Sun*, 2016
SPECT imaging of cytochrome c in pressure overload mice hearts, Wang, C., X. Li, C. Shen, L.L. Ma, Z. Dong, H. Zhu, P. Wang, J.B. Ge, and A. Sun*, 2016
Trans-Fatty Acids Aggravate Obesity, Insulin Resistance and Hepatic Steatosis in C57BL/6 Mice, Possibly by Suppressing the IRS1 Dependent Pathway, Zhao, X., C. Shen, H. Zhu, C. Wang, X. Liu, X. Sun, S. Han, P. Wang, Z. Dong, X. Ma, K. Hu, A. Sun*, and J. Ge*, 2016
Mitochondrial Aldehyde Dehydrogenase 2 Regulates Revascularization in Chronic Ischemia: Potential Impact on the Development of Coronary Collateral Circulation, Liu, X., X. Sun, H. Liao, Z. Dong, J. Zhao, H. Zhu, P. Wang, L. Shen, L. Xu, X. Ma, C. Shen, F. Fan, C. Wang, K. Hu, Y. Zou, J. Ge, J. Ren, and A. Sun*, 2015
Acetaldehyde dehydrogenase 2 (ALDH2) deficiency exacerbates pressure overload-induced cardiac dysfunction by inhibiting Beclin-1 dependent autophagy pathway, Shen, C., C. Wang, F. Fan, Z. Yang, Q. Cao, X. Liu, X. Sun, X. Zhao, P. Wang, X. Ma, H. Zhu, Z. Dong, Y. Zou, K. Hu, A. Sun*, and J. Ge, 2015
Aberrant hypermethylation of aldehyde dehydrogenase 2 promoter upstream sequence in rats with experimental myocardial infarction, Wang, P., C. Shen, L. Diao, Z. Yang, F. Fan, C. Wang, X. Liu, X. Sun, Z. Dong, H. Zhu, X. Ma, Q. Cao, X. Zhao, D. Ma, Y. Zou, K. Hu, A. Sun*, and J. Ge*, 2015
Aldehyde dehydrogenase-2 is a host factor required for effective bone marrow mesenchymal stem cell therapy, Zhu, H., A. Sun*, H. Zhu, Z. Li, Z. Huang, S. Zhang, X. Ma, Y. Zou, K. Hu, and J. Ge*, 2014
Aldehyde dehydrogenase 2 ameliorates doxorubicin-induced myocardial dysfunction through detoxification of 4-HNE and suppression of autophagy, Sun, A.*, Y. Cheng, Y. Zhang, Q. Zhang, S. Wang, S. Tian, Y. Zou, K. Hu, J. Ren, and J. Ge, 2014
Mitochondrial aldehyde dehydrogenase 2 plays protective roles in heart failure after myocardial infarction via suppression of the cytosolic JNK/p53 pathway in mice, Sun, A.*, Y. Zou*, P. Wang, D. Xu, H. Gong, S. Wang, Y. Qin, P. Zhang, Y. Chen, M. Harada, T. Isse, T. Kawamoto, H. Fan, P. Yang, H. Akazawa, T. Nagai, H. Takano, P. Ping, I. Komuro*, and J

Heart Failure Mechanisms Translational Research Mitochondrial Dysfunction Myocardial Injury Metabolic Homeostasis Stem Cell Transplantation Energy Metabolism Cheatocin Cardioprotection

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