Professor | Zhi-Min Shao | Asia Growth Partners

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Name	Zhi-Min Shao
Contact Information	zhimingshao@yahoo.com
Language ability	Chinese, English
Province	Shanghai

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Name

Zhi-Min Shao

Contact Information

zhimingshao@yahoo.com

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Biomedical Sciences
Academic Background & Achievements	1980.9—1985.7 Bachelor's in Clinical Medicine: Shanghai Medical University 1987.9—1990.6 Master's in Oncology: Shanghai Medical University 2000 National Outstanding Youth Fund Recipient 2004 Ministry of Health Outstanding Young and Middle-aged Expert 2005 Shanghai 'Top Ten Science and Technology Elites' Title 2006 Guanghua Engineering Award
Work Experience	1985.7-1990.7 - Shanghai Medical University Cancer Hospital - Surgeon 1990.8-1991.8 - Bowman Gray School of Medicine Cancer Center, USA - Breast Cancer Researcher 1991.9-1995.6 - University of Maryland Cancer Center, USA - Advanced Studies 1995.12-1998.4 - Shanghai Medical University Cancer Hospital - Promoted to Associate Researcher 1998.5 - Shanghai Medical University Cancer Hospital - Promoted to Researcher 1997.2-2000.6 - University of California, Los Angeles Breast Center, USA - Visiting Professor 2000.8-present - Fudan University Cancer Hospital - Director of Breast Surgery 2002.5-present - Fudan University Breast Cancer Research Institute - Director 2003.12-present - Fudan University Cancer Hospital - Professor 2005.6-present - Fudan University Cancer Hospital - Director of General Surgery 2012.8-present - Fudan University Cancer Research Institute - Director
Awards	2014.9: First Prize of the Chinese Anti-Cancer Association Science and Technology Award 2012.2.10: Second Prize of the Ministry of Education Science and Technology Progress Award 2011.11.23: First Prize of the Shanghai Science and Technology Progress Award 2009.1: First Prize of the Ministry of Education Science and Technology Progress Award 2009.11: Second Prize of the Shanghai Science and Technology Progress Award 2008.12: Third Prize of the Chinese Medical Science and Technology Award 2004.1: Third Prize of the Chinese Medical Science and Technology Award 2005.1: Second Prize of the National Science and Technology Progress Award 2006.11: Third Prize of the Shanghai Science and Technology Progress Award

University/Lab Affiliation and Title

Fudan University

Faculty

Biomedical Sciences

Academic Background & Achievements

1980.9—1985.7 Bachelor's in Clinical Medicine: Shanghai Medical University
1987.9—1990.6 Master's in Oncology: Shanghai Medical University
2000 National Outstanding Youth Fund Recipient
2004 Ministry of Health Outstanding Young and Middle-aged Expert
2005 Shanghai 'Top Ten Science and Technology Elites' Title
2006 Guanghua Engineering Award

Work Experience

1985.7-1990.7 - Shanghai Medical University Cancer Hospital - Surgeon
1990.8-1991.8 - Bowman Gray School of Medicine Cancer Center, USA - Breast Cancer Researcher
1991.9-1995.6 - University of Maryland Cancer Center, USA - Advanced Studies
1995.12-1998.4 - Shanghai Medical University Cancer Hospital - Promoted to Associate Researcher
1998.5 - Shanghai Medical University Cancer Hospital - Promoted to Researcher
1997.2-2000.6 - University of California, Los Angeles Breast Center, USA - Visiting Professor
2000.8-present - Fudan University Cancer Hospital - Director of Breast Surgery
2002.5-present - Fudan University Breast Cancer Research Institute - Director
2003.12-present - Fudan University Cancer Hospital - Professor
2005.6-present - Fudan University Cancer Hospital - Director of General Surgery
2012.8-present - Fudan University Cancer Research Institute - Director

Awards

2014.9: First Prize of the Chinese Anti-Cancer Association Science and Technology Award
2012.2.10: Second Prize of the Ministry of Education Science and Technology Progress Award
2011.11.23: First Prize of the Shanghai Science and Technology Progress Award
2009.1: First Prize of the Ministry of Education Science and Technology Progress Award
2009.11: Second Prize of the Shanghai Science and Technology Progress Award
2008.12: Third Prize of the Chinese Medical Science and Technology Award
2004.1: Third Prize of the Chinese Medical Science and Technology Award
2005.1: Second Prize of the National Science and Technology Progress Award
2006.11: Third Prize of the Shanghai Science and Technology Progress Award

Areas of Focus	Breast Cancer Clinical and Basic Research Early Screening and Diagnosis Processes for Chinese Population Clinical Trials to Improve Prognosis of Breast Cancer Patients Translational Research in Breast Cancer Mechanisms of Breast Cancer Metastasis
Publications	Transcriptome Analysis of Triple-Negative Breast Cancer Reveals an Integrated mRNA-lncRNA Signature with Predictive and Prognostic Value., Jiang, Y. Z., Liu, Y. R., Xu, X. E., Jin, X., Hu, X., Yu, K. D., and Shao, Z. M., 2016 Enriched variations in TEKT4 and breast cancer resistance to paclitaxel., Jiang YZ, Yu KD, Peng WT, Di GH, Wu J, Liu GY, Shao ZM., 2014 Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients., Chen L, Yang L, Yao L, Kuang XY, Zuo WJ, Li S, Qiao F, Liu YR, Cao ZG, Zhou SL, Zhou XY, Yang WT, Shi JX, Huang W, Hu X, Shao ZM., 2018 Dual Characteristics of Novel HER2 Kinase Domain Mutations in Response to HER2-Targeted Therapies in Human Breast Cancer., Zuo WJ, Jiang YZ, Wang YJ, Xu XE, Hu X, Liu GY, Wu J, Di GH, Yu KD, Shao ZM., 2016 Comprehensive Transcriptome Profiling Reveals Multigene Signatures in Triple-Negative Breast Cancer., Liu YR, Jiang YZ, Xu XE, Hu X, Yu KD, Shao ZM., 2016 Favorable prognostic impact in loss of TP53 and PIK3CA mutations after neoadjuvant chemotherapy in breast cancer., Jiang YZ, Yu KD, Bao J, Peng WT, Shao ZM., 2014 Cytidine Deaminase Axis Modulated by miR-484 Differentially Regulates Cell Proliferation and Chemoresistance in Breast Cancer., Ye FG, Song CG, Cao ZG, Xia C, Chen DN, Chen L, Li S, Qiao F, Ling H, Yao L, Hu X, Shao ZM., 2015 PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression., Zheng YZ, Xue MZ, Shen HJ, Li XG, Ma D, Gong Y, Liu YR, Qiao F, Xie HY, Lian B, Sun WL, Zhao HY, Yao L, Zuo WJ, Li DQ, Wang P, Hu X, Shao ZM., 2018 Molecular essence and endocrine responsiceness of estrogen receptor-negative, progesterone receptor-positive and HER2-negative breast cancer., Yu KD, Jiang YZ, Hao S, Shao ZM., 2015 Cisplatin plus gemcitabine versus paclitaxel plus gemcitabine as first-line therapy for metastatic triple-negative breast cancer (CBCSG006): a randomised, open-label, multicentre, phase 3 trial., Hu XC, Zhang J, Xu BH, Cai L, Ragaz J, Wang ZH, Wang BY, Teng YE, Tong ZS, Pan YY, Yin YM, Wu CP, Jiang ZF, Wang XJ, Lou GY, Liu DG, Feng JF, Luo JF, Sun K, Gu YJ, Wu J, Shao ZM., 2015 Genomic and Transcriptomic Landscape of Triple-Negative Breast Cancers: Subtypes and Treatment Strategies., Yi-Zhou Jiang, Ding Ma, Chen Suo, Jinxiu Shi, Mengzhu Xue, Xin Hu, Yi Xiao, Ke-Da Yu, Yi-Rong Liu, Ying Yu, Yuanting Zheng, Xiangnan Li, Chenhui Zhang, Pengchen Hu, Jing Zhang, Qi Hua, Jiyang Zhang, Wanwan Hou, Luyao Ren, Ding Bao, Bingying Li, Jingcheng Yang, Ling Yao, Wen-Jia Zuo, Shen Zhao, Yue Gong, Yi-Xing Ren, Ya-Xin Zhao, Yun-Song Yang, Zhenmin Niu, Zhi-Gang Cao, Daniel G. Stover, Claire Verschraegen, Virginia Kaklamani, Anneleen Daemen, John R. Benson, Kazuaki Takabe, Fan Bai, Da-Qiang Li, Peng Wang, Leming Shi, Wei Huang, and Zhi-Ming Shao., 2019 The endogenous retrovirus-derived long noncoding RNA TROJAN promotes triple-negative breast cancer progression via ZMYND8 degradation., Xi Jin, Xiao-En Xu, Yi-Zhou Jiang, Yi-Rong Liu, Wei Sun, Ya-Jie Guo, Yi-Xing Ren, Wen-Jia Zuo, Xin Hu, Sheng-Lin Huang, Hong-Jie Shen, Fei Lan, Yun-Fei He, Guo-Hong Hu, Gen-Hong Di, Xiang-Huo He, Da-Qiang Li, Suling Liu, Ke-Da Yu, Zhi-Ming Shao., 2019 Multi-omics profiling reveals distinct microenvironment characterization and suggests immuneescape mechanisms of triple-negative breast cancer., Xiao Y, Ma D, Zhao S, Suo C, Shi J, Xue MZ, Ruan M, Wang H, Zhao J, Li Q, Wang P, Shi L, Yang WT, Huang W, Hu X, Yu K, Huang S, Bertucci F, Jiang YZ, Shao ZM., 2019

Areas of Focus

Breast Cancer Clinical and Basic Research
Early Screening and Diagnosis Processes for Chinese Population
Clinical Trials to Improve Prognosis of Breast Cancer Patients
Translational Research in Breast Cancer
Mechanisms of Breast Cancer Metastasis

Publications

Transcriptome Analysis of Triple-Negative Breast Cancer Reveals an Integrated mRNA-lncRNA Signature with Predictive and Prognostic Value., Jiang, Y. Z., Liu, Y. R., Xu, X. E., Jin, X., Hu, X., Yu, K. D., and Shao, Z. M., 2016
Enriched variations in TEKT4 and breast cancer resistance to paclitaxel., Jiang YZ, Yu KD, Peng WT, Di GH, Wu J, Liu GY, Shao ZM., 2014
Characterization of PIK3CA and PIK3R1 somatic mutations in Chinese breast cancer patients., Chen L, Yang L, Yao L, Kuang XY, Zuo WJ, Li S, Qiao F, Liu YR, Cao ZG, Zhou SL, Zhou XY, Yang WT, Shi JX, Huang W, Hu X, Shao ZM., 2018
Dual Characteristics of Novel HER2 Kinase Domain Mutations in Response to HER2-Targeted Therapies in Human Breast Cancer., Zuo WJ, Jiang YZ, Wang YJ, Xu XE, Hu X, Liu GY, Wu J, Di GH, Yu KD, Shao ZM., 2016
Comprehensive Transcriptome Profiling Reveals Multigene Signatures in Triple-Negative Breast Cancer., Liu YR, Jiang YZ, Xu XE, Hu X, Yu KD, Shao ZM., 2016
Favorable prognostic impact in loss of TP53 and PIK3CA mutations after neoadjuvant chemotherapy in breast cancer., Jiang YZ, Yu KD, Bao J, Peng WT, Shao ZM., 2014
Cytidine Deaminase Axis Modulated by miR-484 Differentially Regulates Cell Proliferation and Chemoresistance in Breast Cancer., Ye FG, Song CG, Cao ZG, Xia C, Chen DN, Chen L, Li S, Qiao F, Ling H, Yao L, Hu X, Shao ZM., 2015
PHF5A Epigenetically Inhibits Apoptosis to Promote Breast Cancer Progression., Zheng YZ, Xue MZ, Shen HJ, Li XG, Ma D, Gong Y, Liu YR, Qiao F, Xie HY, Lian B, Sun WL, Zhao HY, Yao L, Zuo WJ, Li DQ, Wang P, Hu X, Shao ZM., 2018
Molecular essence and endocrine responsiceness of estrogen receptor-negative, progesterone receptor-positive and HER2-negative breast cancer., Yu KD, Jiang YZ, Hao S, Shao ZM., 2015
Cisplatin plus gemcitabine versus paclitaxel plus gemcitabine as first-line therapy for metastatic triple-negative breast cancer (CBCSG006): a randomised, open-label, multicentre, phase 3 trial., Hu XC, Zhang J, Xu BH, Cai L, Ragaz J, Wang ZH, Wang BY, Teng YE, Tong ZS, Pan YY, Yin YM, Wu CP, Jiang ZF, Wang XJ, Lou GY, Liu DG, Feng JF, Luo JF, Sun K, Gu YJ, Wu J, Shao ZM., 2015
Genomic and Transcriptomic Landscape of Triple-Negative Breast Cancers: Subtypes and Treatment Strategies., Yi-Zhou Jiang, Ding Ma, Chen Suo, Jinxiu Shi, Mengzhu Xue, Xin Hu, Yi Xiao, Ke-Da Yu, Yi-Rong Liu, Ying Yu, Yuanting Zheng, Xiangnan Li, Chenhui Zhang, Pengchen Hu, Jing Zhang, Qi Hua, Jiyang Zhang, Wanwan Hou, Luyao Ren, Ding Bao, Bingying Li, Jingcheng Yang, Ling Yao, Wen-Jia Zuo, Shen Zhao, Yue Gong, Yi-Xing Ren, Ya-Xin Zhao, Yun-Song Yang, Zhenmin Niu, Zhi-Gang Cao, Daniel G. Stover, Claire Verschraegen, Virginia Kaklamani, Anneleen Daemen, John R. Benson, Kazuaki Takabe, Fan Bai, Da-Qiang Li, Peng Wang, Leming Shi, Wei Huang, and Zhi-Ming Shao., 2019
The endogenous retrovirus-derived long noncoding RNA TROJAN promotes triple-negative breast cancer progression via ZMYND8 degradation., Xi Jin, Xiao-En Xu, Yi-Zhou Jiang, Yi-Rong Liu, Wei Sun, Ya-Jie Guo, Yi-Xing Ren, Wen-Jia Zuo, Xin Hu, Sheng-Lin Huang, Hong-Jie Shen, Fei Lan, Yun-Fei He, Guo-Hong Hu, Gen-Hong Di, Xiang-Huo He, Da-Qiang Li, Suling Liu, Ke-Da Yu, Zhi-Ming Shao., 2019
Multi-omics profiling reveals distinct microenvironment characterization and suggests immuneescape mechanisms of triple-negative breast cancer., Xiao Y, Ma D, Zhao S, Suo C, Shi J, Xue MZ, Ruan M, Wang H, Zhao J, Li Q, Wang P, Shi L, Yang WT, Huang W, Hu X, Yu K, Huang S, Bertucci F, Jiang YZ, Shao ZM., 2019

Breast Cancer Clinical Research Basic Research Early Screening Diagnosis Chinese Population Clinical Trials Prognosis Translational Research Metastasis

Lunxiu Qin - Fudan University

Zhaoyou Tang - Fudan University

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