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Xiangdong Fang
fangxd@big.ac.cn
Chinese, English
Beijing
University of Chinese Academy of Sciences
Life Sciences
  • 1996-09--1999-07 PhD in Human Anatomy and Embryology: First Military Medical University
  • 1992-09--1995-07 Master's in Immunology: First Military Medical University
  • 1986-09--1992-07 Bachelor's in Clinical Medicine: First Military Medical University
  • 2009-01~Present - Chinese Academy of Sciences Beijing Institute of Genomics - Researcher, Doctoral Supervisor
  • 2000-05~2009-01 - Washington University School of Medicine - Postdoctoral, Lecturer, Research Assistant Professor
  • 2013: Excellent Course Award for 'Frontiers in Genomics' by the School of Life Sciences, University Level
  • 2010: Chinese Academy of Sciences Knowledge Innovation Project '****' Preferential Support, University Level
  • 1999: Shanghai Science and Technology Progress Award, Third Prize, Provincial Level
  • 1995: Guangdong Science and Technology Progress Award, Second Prize, Provincial Level
Genomic Big Data and Precision Medicine Research
Epigenetic Regulatory Networks of Cell Differentiation
Translation and Application of Genomic Research
  • CROST: a comprehensive repository of spatial transcriptomics, Wang, Guoliang, Wu, Song, Xiong, Zhuang, Qu, Hongzhu, Fang, Xiangdong, Bao, Yiming, 2023
  • 大型队列数据资源及其研究方法综述, 葛令乔, 渠鸿竹, 方向东, 2023
  • 痛风的多组学研究进展, 时文睿, 渠鸿竹, 方向东, 2023
  • DNA methylation-based age prediction with bloodstains using pyrosequencing and random forest regression, Fenglong Yang, Jialin Qian, Hongzhu Qu, Xiangdong Fang, 2023
  • DeteX: A highly accurate software for detecting SNV and InDel in single and paired NGS data in cancer research, Cui, Yunlong, Li, Hongfeng, Liu, Pengfei, Wang, Hailong, Zhang, Zhenzhen, Qu, Hongzhu, Tian, Caijuan, Fang, Xiangdong, 2023
  • A deep learning model for early risk prediction of heart failure with preserved ejection fraction by DNA methylation profiles combined with clinical features, Zhao, Xuetong, Sui, Yang, Ruan, Xiuyan, Wang, Xinyue, He, Kunlun, Dong, Wei, Qu, Hongzhu, Fang, Xiangdong, 2022
  • ANTXR1 Regulates Erythroid Cell Proliferation and Differentiation through wnt β -Catenin Signaling Pathway In Vitro and in Hematopoietic Stem Cell, Tingting Jin, Zhaojun Zhang, Yuanyuan Han, Di Li, Juan Liu, Minmin Jiang, Ryo Kurita, Yukio Nakamura, Fangfang Hu, Xiangdong Fang, Shengwen Huang, Zhaolin Sun, 2022
  • Transmembrane Protein ANTXR1 Regulates γ -Globin Expression by Targeting the Wnt β -Catenin Signaling Pathway, Tingting Jin, Zhaojun Zhang, Yuanyuan Han, Di Li, Juan Liu, Minmin Jiang, Junwei Zhu, Ryo Kurita, Yukio Nakamura, Fangfang Hu, Yongjie Xu, Xiangdong Fang, Shengwen Huang, Zhaolin Sun, 2022
  • Comparison of transcriptome profiles of nucleated red blood cells in cord blood between preterm and full-term neonates, Han, Yuanyuan, Huang, Ling, Zhou, Man, Tan, Xiaoyu, Gong, Shangjin, Zhang, Zhaojun, Jin, Tingting, Fang, Xiangdong, Jia, Yankai, Huang, S W, 2022
  • Single-cell RNA sequencing reveals the cellular and molecular changes that contribute to the progression of lung adenocarcinoma, Liu, Bing, Wang, Chen, Fang, Zhanjie, Bai, Jing, Qian, Ying, Ma, Yuanyuan, Ruan, Xiuyan, Yan, Shi, Li, Shaolei, Wang, Yaqi, Dong, Bin, Yang, Xin, Li, Meng, Xia, Xuefeng, Qu, Hongzhu, Fang, Xiangdong, Wu, Nan, 2022
  • CRISPR/Cas9-based multiplex genome editing of BCL11A and HBG efficiently induces fetal hemoglobin expression, Han, Yuanyuan, Tan, Xiaoyu, Jin, Tingting, Zhao, Siqi, Hu, Li, Zhang, Wei, Kurita, Ryo, Nakamura, Yukio, Liu, Juan, Li, Di, Zhang, Zhaojun, Fang, Xiangdong, Huang, Shengwen, 2022
  • Mapping the single-cell landscape of acral melanoma and analysis of the molecular regulatory network of the tumor microenvironments, Zan He, Zijuan Xin, Qiong Yang, Chen Wang, Meng Li, Wei Rao, Zhimin Du, Jia Bai, Zixuan Guo, Xiuyan Ruan, Zhaojun Zhang, Xiangdong Fang, Hua Zhao, 2022
  • Mapping Human Pluripotent Stem Cell-derived Erythroid Differentiation by Single-cell Transcriptome Analysis, Xin, Zijuan, Zhang, Wei, Gong, Shangjin, Zhu, Junwei, Li, Yanming, Zhang, Zhaojun, Fang, Xiangdong, 2021
  • 中国人类遗传资源与生物大数据, 方向东, 2021
  • 组学大数据和医学人工智能, 王昕玥, 渠鸿竹, 方向东, 2021
  • Regulatory association of long noncoding RNAs and chromatin accessibility facilitates erythroid differentiation, Ren, Yunxiao, Zhu, Junwei, Han, Yuanyuan, Li, Pin, Wu, Jing, Qu, Hongzhu, Zhang, Zhaojun, Fang, Xiangdong, 2021
  • Construction of competing endogenous RNA interaction network as prognostic markers in metastatic melanoma, He, Zan, Xin, Zijuan, Peng, Yongfei, Zhao, Hua, Fang, Xiangdong, 2021
  • Genome sequencing of pancreatic cancer: differential expression by location, Bi, F, Qian, Y, Song, L, Qu, H, Zheng, J, Fang, X, He, T, Yan, H, 2021
  • Platform-independent approach for cancer detection from gene expression profiles of peripheral blood cells, Yang, Yadong, Zhang, Tao, Xiao, Rudan, Hao, Xiaopeng, Zhang, Huiqiang, Qu, Hongzhu, Xie, Bingbing, Wang, Tao, Fang, Xiangdong, 2020
  • Increased expression of CXCL2 in ACPA‐positive rheumatoid arthritis and its role in osteoclastogenesis, X Wang, L Sun, N He, Z An, R Yu, C Li, Y Li, Y Li, X Liu, X Fang, J Zhao, 2020
  • Big Data and the Brain: Peeking at the Future, Hongzhu Qu, Hongxing Lei, Xiangdong Fang, 2019
  • 基因编辑技术及其在基因治疗中的应用, 任云晓, 肖茹丹, 娄晓敏, 方向东, 2019
  • GliomaDB: A Web Server for Integrating Glioma Omics Data and Interactive Analysis, Yadong Yang, Yang Sui, Bingbing Xie, Hongzhu Qu, Xiangdong Fang, 2019
  • TRIM44 is indispensable for glioma cell proliferation and cell cycle progression through AKT/p21/p27 signaling pathway, Zhou, Xia, Yang, Yadong, Ma, Pengcheng, Wang, Na, Yang, Dong, Tu, Qiu, Sun, Bin, Xiang, Tingxiu, Zhao, Xudong, Hou, Zongliu, Fang, Xiangdong, 2019
  • Photodynamic Therapy for Genital Warts Causes Activation of Local Immunity, Xie, Fang, Yu, Haisheng S, Wang, Rui, Wang, Dong, Li, Yanming M, Wen, Haiying Y, Du, Jiangbo B, Ba, Wei, Meng, Xianfu F, Yang, Jie, Lin, Biwen W, Li, Hengjin J, Li, Chengxin X, Zhang, Liguo G, Fang, Xiangdong D, Zhao, Hua, 2019
  • Knockdown of SSATX, an alternative splicing variant of the SAT1 gene, promotes melanoma progression, Yang, Qiong, Deng, Youhui, Xu, Yuanyuan, Ding, Nan, Wang, Chen, Zhao, Xuetong, Lou, Xiaomin, Li, Yongjun, Zhao, Hua, Fang, Xiangdong, 2019
  • GliomaDB: a Web Server for Integrating Glioma Omics Data and Interactive Analysis, Qu Hongzhu, 2018
  • KLF1和KLF9对K562细胞红系分化的协同调控作用, 任岚, 肖茹丹, 张倩, 娄晓敏, 张昭军, 方向东, 2018
  • 基因编辑在镰状细胞贫血症治疗中的研究进展, 肖茹丹, 任云晓, 张昭军, 方向东, 2018
  • 组学时代下机器学习方法在临床决策支持中的应用, 赵学彤, 杨亚东, 渠鸿竹, 方向东, 2018
  • MOBCdb: a comprehensive database for integrating multi-omics data on breast cancer for precision medicine, Fang Xiangdong, 2018
  • Research progress on liquid biopsy in oncology and its clinical applications, Fang Xiangdong, 2017
  • MicroRNA 200a inhibits erythroid differentiation by targeting PDCD4 and THRB, Li, Yanming, Zhang, Qian, Du, Zhenglin, Lu, ZhiChao, Liu, Shuge, Zhang, Lu, Ding, Nan, Bao, Binghao, Yang, Yadong, Xiong, Qian, Wang, Hai, Zhang, Zhaojun, Qu, Hongzhu, Jia, Haibo, Fang,
Genomics Big Data Precision Medicine Epigenetics Cell Differentiation Regulatory Networks Genomic Research Translation Application Bioinformatics

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