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Guangxia Gao
gaogx@ibp.ac.cn
English, Chinese
Beijing
University of Chinese Academy of Sciences
Life Sciences
  • 1990-09 to 1995-05 PhD: Columbia University
  • 1984-09 to 1988-07 Bachelor's: Peking University
  • 2014-06 to 2017-10 - Institute of Biophysics, Chinese Academy of Sciences - Deputy Director
  • 2012-08 to 2024-03 - Institute of Biophysics, Chinese Academy of Sciences - Director of Key Laboratory of Infection and Immunity
  • 2005-02 to Present - Institute of Biophysics, Chinese Academy of Sciences - Researcher
  • 2005-02 to 2014-06 - Institute of Biophysics, Chinese Academy of Sciences - Assistant Director
  • 2001-08 to 2005-01 - Institute of Microbiology, Chinese Academy of Sciences - Researcher
  • 1999-08 to 2001-07 - Department of Biochemistry, Columbia University - Associate Research Scientist
  • 1995-08 to 1999-08 - Department of Biochemistry, Columbia University - HHMI Postdoctoral Fellow
  • Innovation Research Group, National Level (2020)
  • Beijing Science and Technology Award, Second Prize, Provincial Level (2013)
  • Special Government Allowance, National Level (2009)
  • National Talent Project, National Level (2007)
  • Outstanding Youth, National Level (2002)
Molecular Virology
  • RNF213 modulates γ-herpesvirus infection and reactivation via targeting the viral Replication and Transcription Activator, 10th Author, 2023
  • TMEM106A inhibits enveloped virus release from cell surface, Corresponding Author, 2022
  • HIV-1 exploits the Fanconi anemia pathway for viral DNA integration, Corresponding Author, 2022
  • TMEM45B Interacts with Sindbis Virus Nsp1 and Nsp4 and Inhibits Viral Replication, Corresponding Author, 2022
  • Molecular Mechanism of RNA Recognition by Zinc-Finger Antiviral Protein, Corresponding Author, 2020
  • Subunit Nanovaccine with Potent Cellular and Mucosal Immunity for COVID-19, 7th Author, 2020
  • Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors, 6th Author, 2020
  • Regulation of HIV-1 Gag-Pol Expression by Shiftless, an Inhibitor of Programmed −1 Ribosomal Frameshifting, Corresponding Author, 2019
  • SUN1 Regulates HIV-1 Nuclear Import in a Manner Dependent on the Interaction between the Viral Capsid and Cellular Cyclophilin A, Corresponding Author, 2018
  • The ER membrane adaptor ERAdP senses the bacterial second messenger c-di-AMP and initiates anti-bacterial immunity, 10th Author, 2018
  • Identification of new type I interferon-stimulated genes and investigation of their involvement in IFN-beta activation, Corresponding Author, 2018
  • The Short Form of the Zinc Finger Antiviral Protein Inhibits Influenza A Virus Protein Expression and Is Antagonized by the Virus-Encoded NS1, Corresponding Author, 2017
  • MicroRNAs recruit eIF4E2 to repress translation of target mRNAs, Corresponding Author, 2017
  • TRIM25 Is Required for the Antiviral Activity of Zinc Finger Antiviral Protein, Corresponding Author, 2017
  • M2BP inhibits HIV-1 virion production in a vimentin filaments-dependent manner, Corresponding Author, 2016
  • Sindbis Virus Can Exploit a Host Antiviral Protein To Evade Immune Surveillance, Corresponding Author, 2016
  • LncBRM initiates YAP1 signalling activation to drive self-renewal of liver cancer stem cells, 8th Author, 2016
  • DNA sensor cGAS-mediated immune recognition, 4th Author, 2016
  • Tristetraprolin Recruits Eukaryotic Initiation Factor 4E2 To Repress Translation of AU-Rich Element-Containing mRNAs, Corresponding Author, 2015
  • HIV-1 Exploits the Host Factor RuvB-like 2 to Balance Viral Protein Expression, Corresponding Author, 2015
  • ZAP Inhibits Murine Gammaherpesvirus 68 ORF64 Expression and Is Antagonized by RTA, Corresponding Author, 2013
  • YB-1 stabilizes HIV-1 genomic RNA and enhances viral production, Corresponding Author, 2013
  • Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase, 7th Author, 2012
  • Expression of YB-1 enhances production of murine leukemia virus vectors by stabilizing genomic viral RNA, Corresponding Author, 2012
  • Zinc Finger Antiviral Protein Inhibits Murine Gammaherpesvirus 68 M2 Expression and Regulates Viral Latency in Cultured Cells, Corresponding Author, 2012
  • Zinc-Finger Antiviral Protein Inhibits XMRV Infection, Corresponding Author, 2012
  • Glycogen Synthase Kinase 3 beta (GSK3 beta) Modulates Antiviral Activity of Zinc-finger Antiviral Protein (ZAP), Corresponding Author, 2012
  • PR65A Regulates The Activity of The Zinc-finger Antiviral Protein, Corresponding Author, 2012
  • Structure of N-terminal domain of ZAP indicates how a zinc-finger protein recognizes complex RNA, 6th Author, 2012
  • Translational repression precedes and is required for ZAP-mediated mRNA decay, Corresponding Author, 2012
  • TANK-Binding Kinase 1 Attenuates PTAP-Dependent Retroviral Budding through Targeting Endosomal Sorting Complex Required for Transport-I, 4th Author, 2011
  • Zinc-finger antiviral protein inhibits HIV-1 infection by selectively targeting multiply spliced viral mRNAs for degradation, Corresponding Author, 2011
  • Hrs inhibits citron kinase-mediated HIV-1 budding via its FYVE domain, Corresponding Author, 2011
  • DEXH-Box protein DHX30 is required for optimal function of the zinc-finger antiviral protein, Corresponding Author, 2010
  • Expression of IMP1 Enhances Production of Murine Leukemia Virus Vector by Facilitating Viral Genomic RNA Packaging, Corresponding Author, 2010
  • Analyses of SELEX-derived ZAP-binding RNA aptamers suggest that the binding specificity is determined by both structure and sequence of the RNA, Corresponding Author, 2010
  • Mutagenesis analysis of the zinc-finger antiviral protein, Corresponding Author, 2010
  • Retroviral restriction factors: new mechanisms of innate immunity, 2nd Author, 2009
  • Genotyping of TRIM5 locus in northern pig-tailed macaques (Macaca leonina), a primate species susceptible to Human Immunodeficiency Virus type 1 infection, 6th Author, 2009
  • Identification of the nonstructural protein 4B of hepatitis C virus as a factor that inhibits the antiviral activity of interferon-alpha, Corresponding Author, 2009
  • ZAP-mediated mRNA degradation, Corresponding Author, 2008
  • P72 DEAD box RNA helicase is required for optimal function of the zinc-finger antiviral protein, Corresponding Author, 2008
  • The zinc-finger antiviral protein recruits the RNA processing exosome to degrade the target mRNA, Corresponding Author, 2007
  • ZAP融合蛋白抑制HIV病毒模型的构建及功能分析, Corresponding Author, 2007
  • ZAP is a CRM1-dependent nucleocytoplasmic shuttling protein, Not mentioned, 2004
  • Isolation of suppressor genes that restore retrovirus susceptibility to a virus-resistant cell line, 2nd Author, 2004
  • The zinc finger antiviral protein directly binds to specific viral mRNAs through the CCCH zinc finger motifs, Not mentioned, 2004
  • Inhibition of Retroviral RNA Production by ZAP, a CCCH-type Antiviral Protein, 1st Author, 2002
Virology Molecular Mechanisms Virus-Host Interactions Ribosomal Frameshifting Gene Identification Functional Analysis Infection Immunity Pathogens Biochemistry

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