Areas of Focus
- Microbial Resource Bioinformatics Mining and Utilization
Work Experience
- 2019-08~Present - Institute of Microbiology, Chinese Academy of Sciences - Researcher, Doctoral Supervisor
- 2014-07~2019-07 - Key Laboratory of Genomic Information and Science, Chinese Academy of Sciences - Director
- 2013-07~2014-07 - Key Laboratory of Genomic Information and Science, Chinese Academy of Sciences - Deputy Director
- 2003-11~2019-07 - Beijing Institute of Genomics, Chinese Academy of Sciences - Researcher, Doctoral Supervisor
- 2002-02~2008-09 - Watson Institute of Genome Sciences, Zhejiang University - Professor, Master's Supervisor
- 1999-08~2003-11 - Human Genome Center, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences - Chief Engineer
- 1998-08~1999-07 - Genome Center, University of Washington, Seattle, USA - Visiting Scholar
- 1996-09~1998-07 - Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences - Assistant Researcher
Academic Background & Achievements
- 1991-09--1996-07 Ph.D. in Biochemistry: China Agricultural University
- 1987-09--1991-07 B.Sc. in Food Engineering: Tianjin University of Commerce
Publications
- VarEPS-Influ:an risk evaluation system of occurred and virtual variations of influenza virus genomes, 11th Author, 2023
- Insights into the genomic evolution and the alkali tolerance mechanisms of Agaricus sinodeliciosus by comparative genomic and transcriptomic analyses, 3rd Author, 2023
- Gut microbiome and mycobiome in inflammatory bowel disease patients with Clostridioides difficile infection, 11th Author, 2023
- Plasmer: an Accurate and Sensitive Bacterial Plasmid Prediction Tool Based on Machine Learning of Shared k-mers and Genomic Features, 11th Author, 2023
- A food poisoning caused by ST7 Staphylococcal aureus harboring sea gene in Hainan province, China, 18th Author, 2023
- Large-scale genomic survey and characterization of mcr genes carried by foodborne Cronobacter isolates, 9th Author, 2023
- Comparative genomic analysis of Fusobacterium nucleatum reveals high intra-species diversity and cgmlst marker construction, 5th Author, 2023
- Improved pea reference genome and pan-genome highlight genomic features and evolutionary characteristics, 4th Author, 2022
- VarEPS: an evaluation and prewarning system of known and virtual variations of SARS-CoV-2 genomes, 11th Author, 2022
- Monitoring microbial communities in intensive care units over one year in China, 11th Author, 2022
- The Dissemination of NDM-1 in Acinetobacter baumannii Strains, 11th Author, 2022
- A genome and gene catalog of glacier microbiomes, 7th Author, 2022
- Amplicon-based sequencing and co-occurence network analysis reveals notable differences of microbial community structure in healthy and dandruff scalps, 11th Author, 2022
- Improved 93-11 Genome and Time-Course Transcriptome Expand Resources for Rice Genomics, 11th Author, 2022
- Central gene transcriptional regulatory networks shaping monocyte development in bone marrow, 11th Author, 2022
- Identification of a Putative CodY Regulon in the Gram-Negative Phylum Synergistetes, 11th Author, 2022
- Genome of the Giant Panda Roundworm Illuminates Its Host Shift and Parasitic Adaptation, 11th Author, 2021
- Association of CYP3A5 Gene Polymorphisms and Amlodipine-Induced Peripheral Edema in Chinese Han Patients with Essential Hypertension, 8th Author, 2021
- A Method for Estimating 24-Hour Urinary Sodium Excretion by Casual Urine Specimen in Chinese Hypertensive Patients, 9th Author, 2021
- Association of CYP3A5 Gene Polymorphisms and Amlodipine-Induced Peripheral Edema in Chinese Han Patients with Essential Hypertension, 11th Author, 2021
- Complete sequences of two new KPC-harbouring plasmids in Klebsiella pneumoniae ST11 strains in China, 11th Author, 2021
- A fine-scale map of genome-wide recombination in divergent Escherichia coli population, 0th Author, 2021
- 5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic and predictive biomarkers for coronary artery disease, 12th Author, 2020
- Expert consensus on microbiome sequencing and analysis, 10th Author, 2020
- The genome evolution and domestication of tropical fruit mango, 11th Author, 2020
- IC4R-2.0: Rice Genome Reannotation Using Massive RNA-seq Data, 11th Author, 2020
- Gene family expansion of pinewood nematode to detoxify its host defence chemicals, 11th Author, 2020
- Identification of a SCN4A mutation in a large Chinese family with atypical normokalemic periodic paralysis using whole-exome sequencing, 2nd Author, 2020
- Structural and Functional Annotation of Transposable Elements Revealed a Potential Regulation of Genes Involved in Rubber Biosynthesis by TE-Derived siRNA Interference in Hevea brasiliensis, 6th Author, 2020
- Post-transcriptional regulation of several biological processes involved in latex production in Hevea brasiliensis, 12th Author, 2020
- A Reference Genome of Bursaphelenchus mucronatus Provides New Resources for Revealing Its Displacement by Pinewood Nematode, 10th Author, 2020
- Abundant Taxa and Favorable Pathways in the Microbiome of Soda-Saline Lakes in Inner Mongolia, 10th Author, 2020
- Genome Assembly and Pathway Analysis of Edible Mushroom Agrocybe cylindracea, 11th Author, 2020
- Semi-rational mutagenesis of an industrial Streptomyces fungicidicus strain for improved enduracidin productivity, 12th Author, 2020
- Editome Disease Knowledgebase (EDK): a curated knowledgebase of editome-disease associations in human, 12th Author, 2019
- Genome structure and evolution of Antirrhinum majus L, 31st Author, 2019
- The HuangZaoSi Maize Genome Provides Insights into Genomic Variation and Improvement History of Maize, 11th Author, 2019
- Evolview v3: a webserver for visualization, annotation, and management of phylogenetic trees, 11th Author, 2019
- Transcriptomic profiling reveals MEP pathway contributing to ginsenoside biosynthesis in
Awards
- Hebei Province Science and Technology Progress Third Prize (2015): Provincial Level
- Tangshan City Science and Technology Progress Second Prize (2015): City Level
- State Council Special Allowance (2014): National Level
- Zhu Li Yuehua Excellent Teacher Award, Chinese Academy of Sciences (2008): Institute Level
- First Prize in Zhejiang Province Science and Technology for Large-Scale Cloning of Functional Genes in Silkworm Using EST Information Resources (2007): Provincial Level
- Excellent Teacher Award, Chinese Academy of Sciences (2006): Institute Level
- Outstanding Scientific Achievement Collective Award for Hybrid Rice Genome Project, Chinese Academy of Sciences (2003): Institute Level
- Qiu Shi Outstanding Scientific Achievement Collective Award for Hybrid Rice Genome Project, Hong Kong Qiu Shi Science and Technology Foundation (2002): Other