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Chengsheng Wu
Life Science
University of Chinese Academy of Sciences
Beijing
Language: English, Chinese
Tumor
Microenvironment
Non-Tumor Cells
Fibroblasts
Immune Cells
Ecm
Stress
Initiation
Progression
Metastasis
Areas of Focus
- Tumor Microenvironment
- Non-tumor Cell Components
- Tumor Initiation
- Tumor Progression
- Tumor Metastasis
- Molecular Targets
- Cancer Cell Biology
- Molecular Biology
- Biochemistry
- Multi-omics
Work Experience
- 2024-04 to Present - University of Chinese Academy of Sciences - Tenure-Track Assistant Professor
- 2023-02 to 2024-04 - University of California, San Diego - Assistant Project Scientist
Academic Background & Achievements
- 2018-02 to 2023-02 Postdoctoral: University of California, San Diego
- 2012-09 to 2017-06 PhD: University of Alberta
- 2009-09 to 2012-06 Master's: Fudan University
- 2005-09 to 2009-06 Bachelor's: Hefei University of Technology
Publications
- Tumor-initiating cells establish a niche to overcome isolation stress., First Author, 2024
- Integrin αvβ3 Upregulation in Response to Nutrient Stress Promotes Lung Cancer Cell Metabolic Plasticity., Second Author, 2024
- Upregulation of fibronectin and its integrin receptors - an adaptation to isolation stress that facilitates tumor initiation., First Author, 2023
- Pancreatic cancer cells upregulate LPAR4 in response to isolation stress to promote an ECM-enriched niche and support tumour initiation., First Author, 2023
- Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity., Eighth Author, 2020
- Oxidative stress enhances tumorigenicity and stem-like features via the activation of the Wnt/β-catenin/MYC/Sox2 axis in ALK-positive anaplastic large-cell lymphoma., First Author, 2018
- A positive feedback loop involving the Wnt/β-catenin/MYC/Sox2 axis defines a highly tumorigenic cell subpopulation in ALK-positive anaplastic large cell lymphoma., First Author, 2016
- The PI3K/AKT/c-MYC axis promotes the acquisition of cancer stem-like features in esophageal squamous cell carcinoma., First Author, 2016
- STAT1 is phosphorylated and downregulated by the oncogenic tyrosine kinase NPM-ALK in ALK-positive anaplastic large-cell lymphoma., First Author, Cover Article, 2015
