Upload Avatar (500 x 500)
Xianen Zhang
Life Science
University of Chinese Academy of Sciences
Beijing
Language: Chinese, English
Microbiology
Pathogens
Biosensors
Nanobiotechnology
Synthetic Biology
Virus
Bacteria
Immunology
Biochemistry
Molecular Biology
Areas of Focus
- Microbiology
- Pathogenic Microbiology
Work Experience
- 2013-05~Present - Institute of Biophysics, Chinese Academy of Sciences - Researcher
- 2002-01~2013-04 - Ministry of Science and Technology - Director
- 1999-01~2002-01 - Wuhan Branch, Chinese Academy of Sciences - Party Secretary, Deputy Director
- 1996-09~1996-11 - Department of Biochemistry, Imperial College London - Senior Visiting Scholar
- 1994-06~1994-12 - Department of Biochemistry, Imperial College London - Senior Visiting Scholar
- 1993-01~Present - Wuhan Institute of Virology, Chinese Academy of Sciences - Researcher
- 1993-01~1993-12 - University of Hawaii - Senior Visiting Scholar
- 1992-01~1999-01 - Wuhan Institute of Virology, Chinese Academy of Sciences - Deputy Director, Academic Committee Director
- 1989-01~1993-01 - Wuhan Institute of Virology, Chinese Academy of Sciences - Associate Researcher
- 1986-01~1987-01 - Alberta Research Council, Canada - Visiting Scholar
- 1985-07~1988-12 - Wuhan Institute of Virology, Chinese Academy of Sciences - Researcher, Assistant Researcher, Project Leader
Academic Background & Achievements
- 1991-09--1994-07 Ph.D.: Institute of Microbiology, Chinese Academy of Sciences
- 1982-09--1985-07 M.Sc.: Wuhan Institute of Virology, Chinese Academy of Sciences
- 1979-09--1982-07 B.Sc.: Hubei University
Publications
- Altered hACE2 binding affinity and S1/S2 cleavage efficiency of SARS-CoV-2 spike protein mutants affect viral cell entry, Ke Wang, Yu Pan, Dianbing Wang, Ye Yuan, Min Li, Yuanyuan Chen, Lijun Bi, XianEn Zhang, 2023
- Enabling technology and core theory of synthetic biology, Zhang, XianEn, Liu, Chenli, Dai, Junbiao, Yuan, Yingjin, Gao, Caixia, Feng, Yan, Wu, Bian, Wei, Ping, You, Chun, Wang, Xiaowo, Si, Tong, 2023
- Diagnosis of nasopharyngeal carcinoma using an ultrasensitive immunoassay method based on nanoparticles, Gong, Rui, Yang, Chenyang, Abbas, Ghulam, Wang, Dianbing, Zhang, Xianen, Nie, Guohui, Ding, Hui, 2023
- Construction of Genetically Encoded Biosensors to Monitor Subcellular Compartment-Specific Glutathione Response to Chemotherapeutic Drugs in Acute Myeloid Leukemia Cells, Abbas, Ghulam, Cui, Mengmeng, Wang, Dianbing, Li, Min, Zhang, XianEn, 2023
- Two-Dimensional Protein Nanoarray as a Carrier of Sensing Elements for Gold-Based Immunosensing Systems, Tang, Jingya, Zhang, Guimin, Li, Feng, Zeng, Rongyu, Song, Jin, Abbas, Ghulam, Cui, Mengmeng, Zhang, Wei, Zhang, XianEn, Wang, DianBing, 2022
- Genetically encoded redox biosensor system for H2O2 measurement in four subcellular compartments in acute myeloid leukemia (AML) cells, Cui, Mengmeng, Abbas, Ghulam, Wang, Dianbing, Liu, Qian, Gong, Rui, Li, Min, Zhang, XianEn, 2022
- Single-Particle Tracking Reveals the Interplay between HIV-1 Reverse Transcription and Uncoating, Ma, Yingxin, Mao, Guobin, Wu, Guoqiang, Zhang, XianEn, 2022
- Probing cell membrane integrity using a histone-targeting protein nanocage displaying precisely positioned fluorophores, Fang, Ti, Li, Chaoqun, Liang, Ao, Zhang, Hui, Zhang, Fan, Zhang, XianEn, Yang, YiYu, Li, Feng, 2022
- A switch-on molecular biosensor for detection of caspase-3 and imaging of apoptosis of cells, Gong, Rui, Wang, Dianbing, Abbas, Ghulam, Li, Shimin, Liu, Qian, Cui, Mengmeng, Zhang, XianEn, 2022
- Promoter-regulated in vivo asymmetric self-assembly strategy to synthesize heterogeneous nanoparticles for signal amplification, Chen Chen, Juan Zhou, Dong Men, Xian-En Zhang, 2022
- T-Cell Immunoglobulin and Mucin Domain 1 (TIM-1) Is a Functional Entry Factor for Tick-Borne Encephalitis Virus, Xiaowei Zhang, Cuiqin Liang, Hanzhong Wang, Zhengyuan Guo, Heng Rong, Jingdi Pan, Wei Li, Rongjuan Pei, Xinwen Chen, Zhiping Zhang, XianEn Zhang, Zongqiang Cui, 2022
- Dysregulation of Innate and Adaptive Immune Responses in Asymptomatic SARS-CoV-2 Infection with Delayed Viral Clearance, Cao, Shanshan, Zhang, Qing, Song, Liu, Xiao, Mingzhong, Chen, Yexing, Wang, Dianbing, Li, Min, Hu, Jinchao, Lin, Lin, Zheng, Ying, Zhou, Kun, Ye, Shujian, Zhou, Juan, Zhou, Ya Na, Cui, Jing, Wang, Jingzhi, Sun, Jing, Tao, Junxiu, Chen, Zhou, Chen, Rong, Zhou, Peng, Shi, Zhengli, Wei, Sheng, Zhao, Linhua, Wang, Hui, Tong, Xiaoling, Li, Xiaodong, Men, Dong, Hou, Baidong, Zhang, XianEn, 2022
- Synthesis of Dual-Emitting CdZnSe/Mn:ZnS Quantum Dots for Sensing the pH Change in Live Cells, Mao, Guobin, Wu, Guoqiang, Chen, Minghai, Yan, Chuang, Tang, Jingya, Ma, Yingxin, Zhang, XianEn, 2022
- A prototype protein nanocage minimized from carboxysomes with gated oxygen permeability, Ruimin Gao, Huan Tan, Shanshan Li, Shaojie Ma, Yufu Tang, Kaiming Zhang, Zhiping Zhang, Quli Fan, Jun Yang, XianEn Zhang, Feng Li, 2022
- Tracking the Replication-Competent Zika Virus with Tetracysteine-Tagged Capsid Protein in Living Cells, Li, Shimin, Wang, Dianbing, Ghulam, Abbas, Li, Xia, Li, Min, Li, Qin, Ma, Yingxin, Wang, Lei, Wu, Hangshen, Cui, Zongqiang, Zhang, XianEn, 2022
- Progress in wearable sweat sensors and their applications, Zhou, Juan, Men, Dong, Zhang, XianEn, 2022
- Sustainability of SARS-CoV-2 Induced Humoral Immune Responses in COVID-19 Patients from Hospitalization to Convalescence Over Six Months, Zheng, Yang, Zhang, Qing, Ali, Ashaq, Li, Ke, Shao, Nan, Zhou, Xiaoli, Ye, Zhiqin, Chen, Xiaomin, Cao, Shanshan, Cui, Jing, Zhou, Juan, Wang, Dianbing, Hou, Baidong, Li, Min, Cui, Mengmeng, Deng, Lihua, Sun, Xinyi, Zhang, Qian, Yang, Qinfang, li, Yong, Wang, Hui, Lei, Yake, Yu, Bo, Cheng, Yegang, Tong, Xiaolin, Men, Dong, Zhang, XianEn, 2021
- A ROS scavenging protein nanocage for in vitro and in vivo antioxidant treatment, Zhu, Weiwei, Fang, Ti, Zhang, Wenjing, Liang, Ao, Zhang, Hui, Zhang, ZhiPing, Zhang, XianEn, Li, Feng, 2021
- CRISPR-dCas9-Guided and Telomerase-Responsive Nanosystem for Precise Anti-Cancer Drug Delivery, Ma, Yingxin, Mao, Guobin, Wu, Guoqiang, Cui, Zongqiang, Zhang, XianEn, Huang, Weiren, 2021
- Auxiliary Module Promotes the Synthesis of Carboxysomes in E. coli to Achieve High-Efficiency CO2 Assimilation, Zhang, Yuwei, Zhou, Juan, Zhang, Yuchen, Liu, Tiangang, Lu, Xiaoyun, Men, Dong, Zhang, XianEn, 2021
- MgrB Inactivation Confers Trimethoprim Resistance in Escherichia coli, Shi, Hongmei, Li, Ting, Xu, Jintian, Yu, Jifang, Yang, Shanshan, Zhang, XianEn, Tao,
Awards
- 2015: First Prize for Research on New Principles of Biosensing, Provincial Level
- 2015: Honorary Doctor of Science Degree, Other
- 1996: First and Second Level National Cross-Century Talents, Ministry Level
- 1994: Outstanding Young and Middle-aged Expert with Outstanding Contributions, Academy Level
- 1989: Third Prize of Scientific and Technological Progress Award, Academy Level
- 1989: First Youth Scientist Award, Academy Level
