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Mingzhao Zhu
zhumz@im.ac.cn
Chinese, English
Beijing
University of Chinese Academy of Sciences
Life Sciences
  • 1998-09--2003-07 PhD: Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences
  • 1994-09--1998-07 Bachelor: School of Life Sciences, Peking University
  • 2023-11~Present - Institute of Microbiology, Chinese Academy of Sciences - Researcher
  • 2009-10~2023-11 - Institute of Biophysics, Chinese Academy of Sciences - Researcher
  • 2009-01~2009-12 - University of Chicago - Research Assistant Professor
  • 2004-01~2008-12 - University of Chicago - Postdoctoral Fellow
  • National Science Fund for Distinguished Young Scholars (2020): National Level
  • Chinese Academy of Sciences Award (2010): Ministerial Level
T cell immunity and vaccine immunity
Lymphoid tissue microenvironment
  • Research progress in mechanism of T cell senescence, Mingzhao Zhu, 2023
  • Endothelial SIRPα signaling controls VE-cadherin endocytosis for thymic homing of progenitor cells, Mingzhao Zhu, 2022
  • Immunological perspectives on spatial and temporal vaccine delivery, Mingzhao Zhu, 2021
  • Exploration of a Sequential Gp140-Gp145 Immunization Regimen with Heterologous Envs to Induce a Protective Cross-Reactive HIV Neutralizing Antibody Response In Non-human Primates, Mingzhao Zhu, 2021
  • Ferritin nanoparticle-based SARS-CoV-2 RBD vaccine induces a persistent antibody response and long-term memory in mice, Mingzhao Zhu, 2021
  • CD146 bound to LCK promotes TCR signaling and anti-tumor immune response in mice, Mingzhao Zhu, 2021
  • Thymic Egress Is Regulated by T Cell-Derived LTβR Signal and via Distinct Thymic Portal Endothelial Cells, Mingzhao Zhu, 2021
  • Type 3 Innate Lymphoid Cells Direct Goblet Cell Differentiation via the LT-LT beta R Pathway during Listeria Infection, Mingzhao Zhu, 2020
  • RelB regulates the homeostatic proliferation but not the function of Tregs, Mingzhao Zhu, 2020
  • TRAF3IP3 at the trans-Golgi network regulates NKT2 maturation via the MEK/ERK signaling pathway, Mingzhao Zhu, 2020
  • H2A.Z facilitates licensing and activation of early replication origins, Mingzhao Zhu, 2020
  • Dual-targeting nanoparticle vaccine elicits a therapeutic antibody response against chronic hepatitis B, Mingzhao Zhu, 2020
  • TRAF3IP3 at the trans-Golgi network regulates NKT2 maturation via MEK/ERK signaling pathway, Mingzhao Zhu, 2019
  • Ferritin nanoparticle-based SpyTag/SpyCatcher-enabled click vaccine for tumor immunotherapy, Mingzhao Zhu, 2019
  • Langerhans cells control lymphatic vessel function during inflammation via direct LIGHT-LTbR signaling, Mingzhao Zhu, 2019
  • Langerhans Cells Control Lymphatic Vessel Function during Inflammation via LIGHT-LT beta R Signaling, Mingzhao Zhu, 2019
  • CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development, Mingzhao Zhu, 2019
  • T cell-derived lymphotoxin limits Th1 response during HSV-1 infection, Mingzhao Zhu, 2018
  • RelB intrinsically regulates the development and function of medullary thymic epithelial cells, Mingzhao Zhu, 2018
  • Differential Roles of LT beta R in Endothelial Cell Subsets for Lymph Node Organogenesis and Maturation, Mingzhao Zhu, 2018
  • T Cell-Derived Lymphotoxin Is Essential for the Anti-Herpes Simplex Virus 1 Humoral Immune Response, Mingzhao Zhu, 2018
  • Salivary factor LTRIN from Aedes aegypti facilitates the transmission of Zika virus by interfering with the lymphotoxin-beta receptor, Mingzhao Zhu, 2018
  • Differential roles of LTbR in endothelial cell subsets for lymph node organogenesis and maturation, Mingzhao Zhu, 2018
  • Salivary factor LTRIN from Aedes aegypti facilitates the transmission of Zika virus by interfering with the lymphotoxin-β receptor, Mingzhao Zhu, 2018
  • RelB intrinsically regulates the development and function of medullary thymic epithelial cells, Mingzhao Zhu, 2018
  • Dual Targeting of Innate and Adaptive Checkpoints on Tumor Cells Limits Immune Evasion, Mingzhao Zhu, 2018
  • Immune cell trafficking and dynamic immunity, Mingzhao Zhu, 2018
  • Dual targeting of innate and adaptive checkpoints on tumor cells limits immune evasion, Mingzhao Zhu, 2018
  • Coordinating antigen cytosolic delivery and danger signaling to program potent cross-priming by micelle-based nanovaccine, Mingzhao Zhu, 2017
  • Lymphotoxin signalling in tertiary lymphoid structures and immunotherapy, Mingzhao Zhu, 2017
  • The mycobacterial phosphatase PtpA regulates the expression of host genes and promotes cell proliferation, Mingzhao Zhu, 2017
  • LTbR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration, Mingzhao Zhu, 2016
  • Lt beta r controls thymic portal endothelial cells for haematopoietic progenitor cell homing and t-cell regeneration, Mingzhao Zhu, 2016
  • A novel dendritic cell targeting HPV16 E7 synthetic vaccine in combination with PD-L1 blockade elicits therapeutic antitumor immunity in mice, Mingzhao Zhu, 2016
  • Herpes virus entry mediator licenses Listeria infection induced immunopathology through control of type I interferon, Mingzhao Zhu, 2015
  • Epithelial lymphotoxin beta receptor regulates embryonic medullary thymic epithelial cell development for central tolerance, Mingzhao Zhu, 2014
  • Recruitment of adult thymic progenitors is regulated by lymphotoxin beta receptor, Mingzhao Zhu, 2014
  • A novel method for synthetic vaccine construction based on protein assembly, Mingzhao Zhu, 2014
  • Lipopolysaccharide Increases the Incidence of Collagen-Induced Arthritis in Mice Through Induction of Protease HTRA-1 Expression, Mingzhao Zhu, 2013
  • Medullary thymic epithelial cells, the indispensable player in central tolerance, Mingzhao Zhu, 2013
  • Proinflammatory IL-17 induces iBALT development, Mingzhao Zhu, 2012
  • Proinflammatory IL-17 induces iBALT development, Mingzhao Zhu, 2012
  • LIGHT Regulates Inflamed Draining Lymph Node Hypertrophy, Mingzhao Zhu, 2011
  • Deflating the Lymph Node, Mingzhao Zhu, 2011
  • The role of core TNF/LIGHT family members in lymph node homeostasis and remodeling, Mingzhao Zhu, 2011
  • Direct and indirect roles of the LT beta R pathway in central tolerance induction, Mingzhao Zhu, 2010
  • The complicated role of NF-kappa B in T-cell selection, Mingzhao Zhu, 2010
  • The complicated role of NF-κB in T-cell selection, Mingzhao Zhu, 2010
  • Promoting Immune Responses by LIGHT in the Face of Abundant Regulatory T Cell Inhibition, Mingzhao Zhu, 2010
  • Targeting lymphotoxin-mediated negative selection to prevent prostate cancer in mice with genetic predisposition, Mingzhao Zhu, 2009
  • Immunoregulation by tumor necrosis factor superfamily member LIGHT, Mingzhao Zhu, 2009
  • Coordinating Development of Medullary Thymic Epithelial Cells, Mingzhao Zhu, 2008
  • Lymphotoxin beta receptor is required for the migration and selection of autoreactive T cells in thymic medulla, Mingzhao Zhu, 2007
  • NF-kappa B2 is required for the establishment of central tolerance through an Aire-dependent pathway, Mingzhao Zhu, 2006
  • Enhancement of Herpes Simplex Virus-1 Glycoprotein-D DNA Vaccine Induced Specific Immune Responses by Coimmunization with Interleukin-2 Genetic Adjuvant, Mingzhao Zhu, 2005
  • Modifid E6E7 gene of HPV increases immunogenicity of human papillomavirus 16
T Cells Immunity Vaccines Immune Response Lymphoid Tissue Microenvironment Immunology Cell Biology Vaccine Development Immune Regulation

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