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Guangkai Bian
Life Science
University of Chinese Academy of Sciences
Guangdong
Language: Chinese, English
Biosynthesis
Biomaterials
Microbiology
Biochemistry
Molecular Biology
Chemical Biology
Terpenes
Gene Clusters
Synthetic Biology
Metabolic Engineering
Areas of Focus
- Biosynthesis
- Biomaterials
Work Experience
- 2022-12 to Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Researcher
- 2022-01 to 2022-11 - Zhongnan Hospital of Wuhan University, Institute of Pharmacy - Researcher
- 2020-01 to 2021-12 - Wuhan University - Associate Researcher
- 2017-07 to 2019-12 - Wuhan University - Postdoctoral Researcher
Academic Background & Achievements
- 2012-09 to 2017-06 PhD: Wuhan University
Publications
- Discovery of non-squalene triterpenes, Third Author, 2022
- Efficient exploration of terpenoid biosynthetic gene clusters in filamentous fungi, Third Author, 2022
- Characterization of Tremulane Sesquiterpene Synthase from the Basidiomycete Irpex lacteus, Eleventh Author, 2022
- Systematic mining of fungal chimeric terpene synthases using an efficient precursor-providing yeast chassis, Eleventh Author, 2021
- Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases, Second Author, 2020
- Semisynthesis of Plant-Derived Englerin A Enabled by Microbe Engineering of Guaia-6,10(14)-diene as Building Block, Third Author, 2020
- Metabolic Engineering-Based Rapid Characterization of a Sesquiterpene Cyclase and the Skeletons of Fusariumdiene and Fusagramineol from Fusarium graminearum, First Author, 2018
- A Clade II-D Fungal Chimeric Diterpene Synthase from Colletotrichum gloeosporioides Produces Dolasta-1(15),8-diene, First Author, 2018
- Production of taxadiene by engineering of mevalonate pathway in Escherichia coli and endophytic fungus Alternaria alternata TPF6, First Author, 2017
- Strategies for terpenoid overproduction and new terpenoid discovery, First Author, 2017
- Releasing the potential power of terpene synthases by a robust precursor supply platform, First Author, 2017
