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Huaqing Cai
huaqingcai@ibp.ac.cn
English, Chinese
Beijing
University of Chinese Academy of Sciences
Life Sciences
  • 2001-09--2007-05 Ph.D. in Science: Yale University
  • 1997-09--2001-07 B.Sc. in Science: Peking University
  • 2015-09~Present - Institute of Biophysics, Chinese Academy of Sciences - Research Group Leader
  • 2013-07~2015-08 - Johns Hopkins University - Research Assistant
  • 2007-10~2013-07 - Johns Hopkins University - Postdoctoral Fellow
Molecular Mechanisms and Physiological Functions of Macropinocytosis
Molecular Mechanisms of Cell Migration and its Relationship with Diseases
  • GxcM-Fbp17/RacC-WASP signaling regulates polarized cortex assembly in migrating cells via Arp2/3., Dong Li, Yihong Yang, Chenglin Lv, Yingjie Wang, Xiaoting Chao, Jiafeng Huang, Shashi P. Singh, Ye Yuan, Chengyu Zhang, Jizhong Lou, Pu Gao, Shanjin Huang, Bo Li, Huaqing Cai, 2023
  • The carboxy terminal transmembrane domain of SPL7 mediates interaction with RAN1 at the endoplasmic reticulum to regulate ethylene signalling in Arabidopsis., Yang, Yanzhi, Hao, Chen, Du, Jianmei, Xu, Lei, Guo, Zhonglong, Li, Dong, Cai, Huaqing, Guo, Hongwei, Li, Lei, 2022
  • Gradients of PI(4,5)P-2 and PI(3,5)P-2 Jointly Participate in Shaping the Back State of Dictyostelium Cells., Li, Dong, Sun, Feifei, Yang, Yihong, Tu, Hui, Cai, Huaqing, 2022
  • An atypical MAPK regulates translocation of a GATA transcription factor in response to chemoattractant stimulation., Hadwiger, Jeffrey A, Cai, Huaqing, Aranda, Ramee G, Fatima, Saher, 2022
  • The PripA-TbcrA complex-centered Rab GAP cascade facilitates macropinosome maturation in Dictyostelium., Tu, Hui, Wang, Zhimeng, Yuan, Ye, Miao, Xilin, Li, Dong, Guo, Hu, Yang, Yihong, Cai, Huaqing, 2022
  • Oligopeptide transporter Slc15A modulates macropinocytosis in Dictyostelium by maintaining intracellular nutrient status., Yiwei Zhang, Hui Tu, Yazhou Hao, Dong Li, Yihong Yang, Ye Yuan, Zhonglong Guo, Lei Li, Haibin Wang, Huaqing Cai, 2022
  • Leep1 interacts with PIP3 and the Scar/WAVE complex to regulate cell migration and macropinocytosis., Yang, Yihong, Li, Dong, Chao, Xiaoting, Singh, Shashi P, Thomason, Peter, Yan, Yonghong, Dong, Mengqiu, Li, Lei, Insall, Robert H, Cai, Huaqing, 2021
  • MicroRNA775 regulates intrinsic leaf size and reduces cell wall pectin levels by targeting a galactosyltransferase gene in Arabidopsis., He Zhang, Zhonglong Guo, Yan Zhuang, Yuanzhen Suo, Jianmei Du, Zhaoxu Gao, Jiawei Pan, Li Li, Tianxin Wang, Liang Xiao, Genji Qin, Yuling Jiao, Huaqing Cai, Lei Li, 2021
  • An Excitable Ras/PI3K/ERK Signaling Network Controls Migration and Oncogenic Transformation in Epithelial Cells., Zhan, Huiwang, Bhattacharya, Sayak, Cai, Huaqing, Iglesias, Pablo A, Huang, ChuanHsiang, Devreotes, Peter N, 2020
  • Statin-induced GGPP depletion blocks macropinocytosis and starves cells with oncogenic defects., Jiao, Zhihua, Cai, Huaqing, Long, Yu, Sirka, Orit Katarina, Padmanaban, Veena, Ewald, Andrew J, Devreotes, Peter N, 2020
  • Laccase3-based extracellular domain provides possible positional information for directing Casparian strip formation in Arabidopsis., Zhuang, Yan, Zuo, Daqing, Tao, Yihan, Cai, Huaqing, Li, Lei, 2020
  • Insight from the maximal activation of the signal transduction excitable network in Dictyostelium discoideum., Edwards, Marc, Cai, Huaqing, AbubakerSharif, Bedri, Long, Yu, Lampert, Thomas J, Devreotes, Peter N, 2018
  • Altering the threshold of an excitable signal transduction network changes cell migratory modes., Miao, Yuchuan, Bhattacharya, Sayak, Edwards, Marc, Cai, Huaqing, Inoue, Takanari, Iglesias, Pablo A, Devreotes, Peter N, 2017
  • The novel RacE-binding protein GflB sharpens Ras activity at the leading edge of migrating cells., Senoo, Hiroshi, Cai, Huaqing, Wang, Yu, Sesaki, Hiromi, Iijima, Miho, 2016
  • G beta Regulates Coupling between Actin Oscillators for Cell Polarity and Directional Migration., Hoeller, Oliver, Toettcher, Jared E, Cai, Huaqing, Sun, Yaohui, Huang, ChuanHsiang, Freyre, Mariel, Zhao, Min, Devreotes, Peter N, Weiner, Orion D, 2016
  • Auxilin facilitates membrane traffic in the early secretory pathway., Ding, Jingzhen, Segarra, Veronica A, Chen, Shuliang, Cai, Huaqing, Lemmon, Sandra K, FerroNovick, Susan, 2016
  • The GATA transcription factor GtaC regulates early developmental gene expression dynamics in Dictyostelium., Santhanam, Balaji, Cai, Huaqing, Devreotes, Peter N, Shaulsky, Gad, KatohKurasawa, Mariko, 2015
  • Nucleocytoplasmic Shuttling of a GATA Transcription Factor Functions as a Development Timer., Cai, Huaqing, KatohKurasawa, Mariko, Muramoto, Tetsuya, Santhanam, Balaji, Long, Yu, Li, Lei, Ueda, Masahiro, Iglesias, Pablo A, Shaulsky, Gad, Devreotes, Peter N, 2014
  • Moving in the right direction: How eukaryotic cells migrate along chemical gradients., Huaqing Cai, Peter N. Devreotes, 2011
  • Ras-mediated activation of the TORC2-PKB pathway is critical for chemotaxis., Cai, Huaqing, Das, Satarupa, Kamimura, Yoichiro, Long, Yu, Parent, Carole A, Devreotes, Peter N, 2010
  • TRAPPI tethers COPII vesicles by binding the coat subunit Sec23p., 蔡华清, 2007
  • Coats, tethers, Rabs, and SNAREs work together to mediate the intracellular destination of a transport vesicle., Cai, Huaqing, Reinisch, Karin, FerroNovick, Susan, 2007
  • PEG介导下香菇的转化(英文)., 林忠平, 许伟宏, 蔡华清, 孙丽, 胡鸢雷, 2001
  • Mutants in trs120 disrupt traffic from the early endosome to the late Golgi., Cai Huaqing, Zhang Yueyi, Pypaert Marc, Walker Lee, Ferro-Novick Susan, 2001
Macropinocytosis Cell Migration Molecular Mechanisms Physiological Functions Nutrient Uptake Immune Response Pathogen Invasion Cancer Tumor Growth Cell Behavior

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