Professor | Liang Chen | Asia Growth Partners

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Name	Liang Chen
Contact Information	liang.chen@siat.ac.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Liang Chen

Contact Information

liang.chen@siat.ac.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2008-09 to 2014-07 PhD: Peking University 2004-09 to 2008-06 Bachelor's: Hebei University
Work Experience	2018-07 to Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher 2014-08 to 2018-06 - University of Pennsylvania - Postdoctoral Researcher
Awards	Patent (2019): TRIM11 gene and protein target and inhibitor in breast cancer, First Author, Patent No: 201910686481.9

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2008-09 to 2014-07 PhD: Peking University
2004-09 to 2008-06 Bachelor's: Hebei University

Work Experience

2018-07 to Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher
2014-08 to 2018-06 - University of Pennsylvania - Postdoctoral Researcher

Awards

Patent (2019): TRIM11 gene and protein target and inhibitor in breast cancer, First Author, Patent No: 201910686481.9

Areas of Focus	Tumor Cell Survival and Apoptosis Tumor Cell Signaling Pathways Tumor Detection and Treatment
Publications	TRIM28 attenuates Bortezomib sensitivity of hepatocellular carcinoma cells through enhanced proteasome expression., Zhang, Jianchao, Fan, Xiaokai, Liao, Lijuan, Zhu, Yan, Wan, Xiaochun, Rao, Hai, Chen, Liang., 2022 Inhibition of AMPK activity by TRIM11 facilitates cell survival of hepatocellular carcinoma under metabolic stress., Liu, Yanfeng, Xu, Yingying, Wang, Fan, Tong, Yu, Li, Hongchang, Wan, Xiaochun, Yang, Xiaolu, Chen, Liang., 2021 Emerging Roles of Tripartite Motif-Containing Family Proteins (TRIMs) in Eliminating Misfolded Proteins., Zhang, Litian, Afolabi, Lukman O, Wan, Xiaochun, Li, Yang, Chen, Liang., 2020 TRIM25 promotes the cell survival and growth of hepatocellular carcinoma through targeting Keap1-Nrf2 pathway., Yanfeng Liu, Shishi Tao, Lijuan Liao, Yang Li, Hongchang Li, Zhihuan Li, Lilong Lin, Xiaochun Wan, Xiaolu Yang, Liang Chen., 2020 TRIM11 cooperates with HSF1 to suppress the anti-tumor effect of proteotoxic stress drugs., Chen, Liang, Yang, Xiaolu., 2019 TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14., Liang Chen, Guixin Zhu, Eleanor M Johns, Xiaolu Yang., 2018 Enhanced Degradation of Misfolded Proteins Promotes Tumorigenesis., Chen, Liang, Brewer, Michael D, Guo, Lili, Wang, Ruoxing, Jiang, Peng, Yang, Xiaolu., 2017 Cab45S promotes cell proliferation through SERCA2b inhibition and Ca2+ signaling., Chen, L, Xu, S, Xu, Y, Lu, W, Liu, L, Yue, D, Teng, J, Chen, J., 2016

Areas of Focus

Tumor Cell Survival and Apoptosis
Tumor Cell Signaling Pathways
Tumor Detection and Treatment

Publications

TRIM28 attenuates Bortezomib sensitivity of hepatocellular carcinoma cells through enhanced proteasome expression., Zhang, Jianchao, Fan, Xiaokai, Liao, Lijuan, Zhu, Yan, Wan, Xiaochun, Rao, Hai, Chen, Liang., 2022
Inhibition of AMPK activity by TRIM11 facilitates cell survival of hepatocellular carcinoma under metabolic stress., Liu, Yanfeng, Xu, Yingying, Wang, Fan, Tong, Yu, Li, Hongchang, Wan, Xiaochun, Yang, Xiaolu, Chen, Liang., 2021
Emerging Roles of Tripartite Motif-Containing Family Proteins (TRIMs) in Eliminating Misfolded Proteins., Zhang, Litian, Afolabi, Lukman O, Wan, Xiaochun, Li, Yang, Chen, Liang., 2020
TRIM25 promotes the cell survival and growth of hepatocellular carcinoma through targeting Keap1-Nrf2 pathway., Yanfeng Liu, Shishi Tao, Lijuan Liao, Yang Li, Hongchang Li, Zhihuan Li, Lilong Lin, Xiaochun Wan, Xiaolu Yang, Liang Chen., 2020
TRIM11 cooperates with HSF1 to suppress the anti-tumor effect of proteotoxic stress drugs., Chen, Liang, Yang, Xiaolu., 2019
TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14., Liang Chen, Guixin Zhu, Eleanor M Johns, Xiaolu Yang., 2018
Enhanced Degradation of Misfolded Proteins Promotes Tumorigenesis., Chen, Liang, Brewer, Michael D, Guo, Lili, Wang, Ruoxing, Jiang, Peng, Yang, Xiaolu., 2017
Cab45S promotes cell proliferation through SERCA2b inhibition and Ca2+ signaling., Chen, L, Xu, S, Xu, Y, Lu, W, Liu, L, Yue, D, Teng, J, Chen, J., 2016

Tumor Cell Survival Apoptosis Signaling Pathways Detection Treatment Cancer Research

Changdong Lin - Tongji University

Haiyun Wang - Tongji University

Ping Chen - Tongji University

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