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Minghai Chen
Life Science
University of Chinese Academy of Sciences
Guangdong
Language: Chinese, English
Biomolecular Interactions
Fluorescence Imaging
Biosensing
Virus-Host Interactions
Synthetic Biology
Protein-Protein Interactions
Rna-Protein Interactions
Sars-Cov-2
Quantum Dots
Bioimaging
Areas of Focus
- Biomolecular Interactions
- Fluorescence Imaging
- Biosensing
- Virus-Host Interactions
Work Experience
- 2019-07 to Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher
- 2017-09 to 2019-07 - University of Virginia - Postdoctoral Researcher
Academic Background & Achievements
- 2012-09 to 2017-07 Ph.D.: Wuhan Institute of Virology, Chinese Academy of Sciences
- 2008-09 to 2012-07 Bachelor's: Henan University
Publications
- Red Emissive Carbon Dot Superoxide Dismutase Nanozyme for Bioimaging and Ameliorating Acute Lung Injury, 8th Author, 2023
- The smallest near-infrared fluorescence complementation system for imaging protein-protein and RNA-protein interactions, 11th Author, 2022
- Characterization and Function of Glycans on the Spike Proteins of SARS-CoV-2 Variants of Concern, 3rd Author, 2022
- Synthesis of Dual-Emitting CdZnSe/Mn:ZnS Quantum Dots for Sensing the pH Change in Live Cells, 3rd Author, 2022
- Near-Infrared Luciferase Complementation Assay with Enhanced Bioluminescence for Studying Protein-Protein Interactions and Drug Evaluation Under Physiological Conditions, 11th Author, 2022
- Dual-Fluorescence Labeling Pseudovirus for Real-Time Imaging of Single SARS-CoV-2 Entry in Respiratory Epithelial Cells, 4th Author, 2021
- Construction and applications of SARS-CoV-2 pseudoviruses: a mini review, 1st Author, 2021
- Long noncoding RNA HOTAIR interacts with Y-Box Protein-1 (YBX1) to regulate cell proliferation, 3rd Author, 2021
- The intraviral protein-protein interaction of SARS-CoV-2 reveals the key role of N protein in virus-like particle assembly, 11th Author, 2021
- A tandem near-infrared fluorescence complementation system with enhanced fluorescence for imaging protein–protein interactions in vivo, 1st Author, 2021
- SARS-CoV-2 spike protein receptor-binding domain N-glycans facilitate viral internalization in respiratory epithelial cells, 3rd Author, 2021
- Nanoscale Imaging of RNA-Protein Interactions with a Photoactivatable Trimolecular Fluorescence Complementation System, 1st Author, 2021
- Genetically Encoded, Photostable Indicators to Image Dynamic Zn 2+ Secretion of Pancreatic Islets, 1st Author, 2019
- ATP-independent bioluminescent reporter variants to improve in vivo imaging, 4th Author, 2019
- Identification of Factors Complicating Bioluminescence Imaging, 3rd Author, 2019
- Three-fragment fluorescence complementation for imaging of ternary complexes under physiological conditions, 1st Author, 2018
- Three-Fragment Fluorescence Complementation Coupled with Photoactivated Localization Microscopy for Nanoscale Imaging of Ternary Complexes., 1st Author, 2016
- Characterization of the Translationally Controlled Tumor Protein (TCTP) Interactome Reveals Novel Binding Partners in Human Cancer Cells, 2nd Author, 2016
- Novel near-infrared BiFC systems from a bacterial phytochrome for imaging protein interactions and drug evaluation under physiological conditions, 1st Author, 2015
Awards
- SIAT-Taikoo Bio-Sensing Award (Young Scientist Award) (2023): Institute
- Outstanding Doctoral Dissertation of the Chinese Academy of Sciences (2018): Institute Level
- President's Award of the Chinese Academy of Sciences (2017): Institute Level
- Outstanding Graduate of the Chinese Academy of Sciences (2017): Institute Level
- National Scholarship (2016): Institute Level
- National Scholarship (2015): Institute Level
