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Chao Shan
Life Science
University of Chinese Academy of Sciences
Hubei
Language: Chinese, English
Vaccine
Development
Pathogen
Diagnosis
Pathogenic
Mechanism
Research
Infectious
Diseases
Virology
Areas of Focus
- Vaccine Development
- Pathogen Diagnosis
- Pathogenic Mechanism Research
Work Experience
- 2015-10 to 2019-12 - University of Texas Medical Branch - Postdoctoral Researcher
- 2014-07 to 2015-08 - Novartis Institute for Tropical Diseases (Singapore) - Research Assistant
Academic Background & Achievements
- 2010-09 to 2014-07 PhD: Wuhan Institute of Virology, Chinese Academy of Sciences
- 2007-09 to 2010-07 Master's: Fujian Agriculture and Forestry University
- 2003-09 to 2007-07 Bachelor's: Qingdao Agricultural University
Publications
- Evolution of Immune Evasion and Host Range Expansion by the SARS-CoV-2 B.1.1.529 (Omicron) Variant, Wenlin Ren, Yu Zhang, Juhong Rao, Ziyi Wang, Jun Lan, Kunpeng Liu, Xuekai Zhang, Xue Hu, Chen Yang, Guocai Zhong, Rong Zhang, Xinquan Wang, Chao Shan, Qiang Ding, XiangJin Meng, 2023
- Japanese Encephalitis Vaccine Generates Cross-Reactive Memory T Cell Responses to Zika Virus in Humans, Wang, Ran, Zhang, Meng, Zhang, Linlin, Liu, Mengjia, Shan, Chao, An, Jing, Xie, Zhengde, 2022
- Recombinant chimpanzee adenovirus vector vaccine expressing the spike protein provides effective and lasting protection against SARS-CoV-2 infection in mice, Mingqing Lu, Kunpeng Liu, Yun Peng, Zhe Ding, Yingwen Li, Alexander Tendu, Xue Hu, Ge Gao, Weiwei Guo, Hang Liu, Juhong Rao, Jiaxuan Zhao, Miaoyu Chen, Zhiming Yuan, Gary Wong, Chao Shan, Yanfeng Yao, Jiaming Lan, 2022
- RNF185 regulates proteostasis in Ebolavirus infection by crosstalk between the calnexin cycle, ERAD, and reticulophagy, Zhang, Jing, Wang, Bin, Gao, Xiaoxiao, Peng, Cheng, Shan, Chao, Johnson, Silas F, Schwartz, Richard C, Zheng, YongHui, 2022
- A potent, broadly protective vaccine against SARS-CoV-2 variants of concern, Wang, Ziyan, An, Jiao, Liu, Kunpeng, Yu, Pin, Fang, Xin, Li, Jiadai, Zhu, Hua, Zhu, Qianjun, Huang, Chuanqi, Zhang, Chao, Zhao, Binbin, Bao, Linlin, Song, Yujiao, Cao, Xiayao, Hu, Dongdong, Jiang, Yuanxiang, Shi, Likang, Zhou, Lingyun, Fan, Jiang, Guan, Wuxiang, Zhou, Chenliang, Hu, Zhongyu, Yuan, Zhiming, Liu, Jiangning, Shan, Chao, Liu, Ge, 2022
- Envelope Protein Ubiquitination Drives Zika Virus Entry and Pathogenesis, Maria I Giraldo, Hongjie Xia, Leopoldo AguileraAguirre, Adam Hage, Sarah van Tol, Chao Shan, Xuping Xie, Gail L Sturdevant, Shelly J Robertson, Kristin L McNally, Kimberly MeadeWhite, Sasha R Azar, Shannan L Rossi, Wendy Maury, Michael Woodson, Holly Ramage, Jeffrey R Johnson, Nevan J Krogan, Marc C Morais, Sonja M Best, PeiYong Shi, Ricardo Rajsbaum, 2020
- Infection with novel coronavirus (SARS-CoV-2) causes pneumonia in Rhesus macaques, Shan, Chao, Yao, YanFeng, Yang, XingLou, Zhou, YiWu, Gao, Ge, Peng, Yun, Yang, Lian, Hu, Xue, Xiong, Jin, Jiang, RenDi, Zhang, HuaJun, Gao, XiaoXiao, Peng, Cheng, Min, Juan, Chen, Ying, Si, HaoRui, Wu, Jia, Zhou, Peng, Wang, YanYi, Wei, HongPing, Pang, Wei, Hu, ZhengFei, Lv, LongBao, Zheng, YongTang, Shi, ZhengLi, Yuan, ZhiMing, 2020
- Role of microglia in the dissemination of Zika virus from mother to fetal brain, Xu, Pei, Shan, Chao, Dunn, Tiffany J, Xie, Xuping, Xia, Hongjie, Gao, Junling, Allende Labastida, Javier, Zou, Jing, Villarreal, Paula P, Schlagal, Caitlin R, Yu, Yongjia, Vargas, Gracie, Rossi, Shannan L, Vasilakis, Nikolaos, Shi, PeiYong, Weaver, Scott C, Wu, Ping, 2020
- Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2, Jiang, RenDi, Liu, MeiQin, Chen, Ying, Shan, Chao, Zhou, YiWu, Shen, XuRui, Li, Qian, Zhang, Lei, Zhu, Yan, Si, HaoRui, Wang, Qi, Min, Juan, Wang, Xi, Zhang, Wei, Li, Bei, Zhang, HuaJun, Baric, Ralph S, Zhou, Peng, Yang, XingLou, Shi, ZhengLi, 2020
- Zika structural genes determine the virulence of African and Asian lineages, Nunes, Bruno T D, FontesGarfias, Camila R, Shan, Chao, Muruato, Antonio E, Nunes, Jannyce G C, Burbano, Rommel M R, Vasconcelos, Pedro F C, Shi, PeiYong, Medeiros, Daniele B A, 2020
- An adenovirus-vectored COVID-19 vaccine confers protection from SARS-COV-2 challenge in rhesus macaques, Feng, Liqiang, Wang, Qian, Shan, Chao, Yang, Chenchen, Feng, Ying, Wu, Jia, Liu, Xiaolin, Zhou, Yiwu, Jiang, Rendi, Hu, Peiyu, Liu, Xinglong, Zhang, Fan, Li, Pingchao, Niu, Xuefeng, Liu, Yichu, Zheng, Xuehua, Luo, Jia, Sun, Jing, Gu, Yingying, Liu, Bo, Xu, Yongcun, Li, Chufang, Pan, Weiqi, Zhao, Jincun, Ke, Changwen, Chen, Xinwen, Xu, Tao, Zhong, Nanshan, Guan, Suhua, Yuan, Zhiming, Chen, Ling, 2020
- Characterization of neutralizing antibody with prophylactic and therapeutic efficacy against SARS-CoV-2 in rhesus monkeys, Wang, Shuang, Peng, Yun, Wang, Rongjuan, Jiao, Shasha, Wang, Min, Huang, Weijin, Shan, Chao, Jiang, Wen, Li, Zepeng, Gu, Chunying, Chen, Ben, Hu, Xue, Yao, Yanfeng, Min, Juan, Zhang, Huajun, Chen, Ying, Gao, Ge, Tang, Peipei, Li, Gang, Wang, An, Wang, Lan, Zhang, Jinchao, Chen, Shuo, Gui, Xun, Yuan, Zhiming, Liu, Datao, 2020
- Novel non-segmented negative-sense RNA virus-based vaccine platforms for Zika virus, Li, Anzhong, Lu, Mijia, Yu, Jingyou, Harder, Olivia, Attia, Zayed, Shan, Chao, Liang, Xueya, Xue, Miaoge, Shi, PeiYong, Peeples, Mark E, Liu, ShanLu, Boyaka, Prosper N, Niewiesk, Stefan, Li, Jianrong, 2020
- A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2, Shi, Rui, Shan, Chao, Duan, Xiaomin, Chen, Zhihai, Liu, Peipei, Song, Jinwen, Song, Tao, Bi, Xiaoshan, Han, Chao, Wu, Lianao, Gao, Ge, Hu, Xue, Zhang, Yanan, Tong, Zhou, Huang, Weijin, Liu, William Jun, Wu, Guizhen, Zhang, Bo, Wang, Lan, Qi, Jianxun, Feng, Hui, Wang, FuSheng, Wang, Qihui, Gao, George Fu, Yuan, Zhiming, Yan, Jinghua, 2020
- A Zika virus envelope mutation preceding the 2015 epidemic enhances virulence and fitness for transmission, Shan, Chao, Xia, Hongjie, Haller, Sherry L, Azar, Sasha R, Liu, Yang, Liu, Jianying, Muruato, Antonio E, Chen, Rubing, Rossi, Shannan L, Wakamiya, Maki, Vasilakis, Nikos, Pei, Rongjuan, FontesGarfias, Camila R, Singh, Sanjay Kumar, Xie, Xuping, Weaver, Scott C, Shi, PeiYong, 2020
- Peli1 signaling blockade attenuates congenital zika syndrome, Huanle Luo, Guangyu Li, Binbin Wang, Bing Tian, Junling Gao, Jing Zou, Shuizhen Shi, Shuang Zhu, BiHung Peng, Awadalkareem Adam, Ariza Martinez, Kimberly Hein, Evandro R Winkelmann, Yoseph Mahmoud, Xiaofei Zhou, Chao Shan, Shannan Rossi, Scott Weaver, Alan D T Barrett, ShaoCong Sun, Wenbo Zhang, PeiYong Shi, Ping Wu, Tian Wang, 2020
- Maternal vaccination and protective immunity against Zika virus vertical transmission, Chao Shan, Xuping Xie, Huanle Luo, Antonio E Muruato, Yang Liu, Maki Wakamiya, JunHo La, Jin Mo Chung, Scott C Weaver, Tian Wang, PeiYong Shi, 2019
- Genetic stability of live-attenuated Zika vaccine candidates, Muruato, Antonio E, Shan, Chao, FontesGarfias, Camila R, Liu, Yang, Cao, Zengguo, Gao, Qiang, Weaver, Scott C, Shi, PeiYong, 2019
- Potential Mechanisms for Enhanced Zika Epidemic and Disease, Xia, Hongjie, Xie, Xuping, Shan, Chao, Shi, PeiYong, 2018
- Using a Virion Assembly-Defective Dengue Virus as a Vaccine Approach, Shan, Chao, Xie, Xuping, Zou, Jing, Zust, Roland, Zhang, Bo, Ambrose, Rebecca, Mackenzie, Jason, Fink, Katja, Shi, PeiYong, 2018
- Zika Virus Vaccine: Progress and Challenges, Shan, Chao, Xie, Xuping, Shi, PeiYong, 2018
- A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage, Chao Shan, Antonio E Muruato, Brett W Jagger, Justin Richner, Bruno T D Nunes, Daniele B A Medeiros, Xuping Xie, Jannyce G C Nunes, Kaitlyn M Morabito, WingPui Kong, Theodore C Pierson, Alan D Barrett, Scott C Weaver, Shannan L Rossi, Pedro F C Vasconcelos, Barney S Graham, Michael S Diamond, PeiYong Shi, 2017
- Functional Analysis of Glycosylation of Zika Virus Envelope Protein, FontesGarfias, Camila R, Shan, Chao, Luo, Huanle, Muruato, Antonio E, Medeiros, Daniele B A, Mays, Elizabeth, Xie, Xuping, Zou, Jing, Roundy, Christopher M, Wakamiya, Maki, Rossi, Shannan L, Wang, Tian, Weaver, Scott C, Shi, PeiYong, 2017
- Evolutionary enhancement of Zika virus infectivity in mosquitos, Chao Shan, 2017
- A live-attenuated Zika virus vaccine candidate induces sterilizing immunity in mouse models, Shan, Chao, Muruato, Antonio E, Nunes, Bruno T D, Luo, Huanle, Xie, Xuping, Medeiros, Daniele B
