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Kelong Fan
fankelong@ibp.ac.cn
Chinese, English
Beijing
University of Chinese Academy of Sciences
Life Sciences
  • 2009-09--2014-07 PhD: University of Chinese Academy of Sciences
  • 2005-09--2009-07 Bachelor: China University of Mining and Technology (Beijing)
  • Achievement 1: First to propose the concept of mimicking natural enzyme active centers for the biomimetic design of nanozymes.
  • Achievement 2: Invented ferritin nanozymes and discovered their unique functions in tumor diagnosis and catalytic therapy.
  • Achievement 3: Discovered temperature-sensitive drug channels in ferritin, advancing drug carrier technology.
  • 2019-07 - Present - Institute of Biophysics, Chinese Academy of Sciences - Researcher
  • 2018-02 - 2019-07 - Institute of Biophysics, Chinese Academy of Sciences - Associate Researcher
  • 2014-08 - 2018-01 - Institute of Biophysics, Chinese Academy of Sciences - Postdoctoral, Associate Researcher (Qualification)
  • Beishizhang Young Biophysicist Award (2019): Other
  • National Upward and Good Youth (2019): National
  • Outstanding Young Scientific Worker of the Chinese Medical Association (2019): Other
  • Outstanding Doctoral Dissertation of the Chinese Academy of Sciences (2015): Institute
  • Special Award of the President of the Chinese Academy of Sciences (2013): Institute
Biomimetic design of nanozymes
Biomedical applications of nanozymes
Ferritin as a drug carrier
  • Protein-Nanocaged Selenium Induces t(8;21) Leukemia Cell Differentiation via Epigenetic Regulation, Fang, Long, Zhang, Ruofei, Shi, Lin, Xie, Jiaying, Ma, Long, Yang, Yili, Yan, Xiyun, Fan, Kelong, 2023
  • Machine learning facilitating the rational design of nanozymes, Li, Yucong, Zhang, Ruofei, Yan, Xiyun, Fan, Kelong, 2023
  • Utilizing nanozymes for combating COVID-19: advancements in diagnostics, treatments, and preventative measures, Wang, Jia, Xie, Qingpeng, Song, Haoyue, Chen, Xiaohang, Zhang, Xiaoxuan, Zhao, Xiangyu, Hao, Yujia, Zhang, Yuan, Li, Huifei, Li, Na, Fan, Kelong, Wang, Xing, 2023
  • 纳米酶, 范克龙, 高利增, 魏辉, 江冰, 王大吉, 张若飞, 贺久洋, 孟祥芹, 王卓然, 樊慧真, 温涛, 段德民, 陈雷, 姜伟, 芦宇, 蒋冰, 魏咏华, 李唯, 袁野, 董海姣, 张鹭, 洪超仪, 张紫霞, 程苗苗, 耿欣, 侯桐阳, 侯亚欣, 李建茹, 汤国恒, 赵越, 赵菡卿, 张帅, 谢佳颖, 周子君, 任劲松, 黄兴禄, 高兴发, 梁敏敏, 张宇, 许海燕, 曲晓刚, 阎锡蕴, 2023
  • Transferrin receptor 1 targeted nanomedicine for brain tumor therapy, Li, Jianru, Zhang, Zixia, Zhang, Baoli, Yan, Xiyun, Fan, Kelong, 2023
  • Surface Ligand Engineering Ruthenium Nanozyme Superior to Horseradish Peroxidase for Enhanced Immunoassay, Fan, Huizhen, Zheng, Jiajia, Xie, Jiaying, Liu, Juewen, Gao, Xingfa, Yan, Xiyun, Fan, Kelong, Gao, Lizeng, 2023
  • Co-based Nanozymatic Profiling: Advances Spanning Chemistry, Biomedical, and Environmental Sciences, Li, Jingqi, Cai, Xinda, Jiang, Peng, Wang, Huayuan, Zhang, Shiwei, Sun, Tiedong, Chen, Chunxia, Fan, Kelong, 2023
  • 纳米酶:一种抗微生物感染新方法, 吴雪彤, 张若飞, 阎锡蕴, 范克龙, 2023
  • Deciphering the catalytic mechanism of superoxide dismutase activity of carbon dot nanozyme, Wenhui Gao, Jiuyang He, Lei Chen, Xiangqin Meng, Yana Ma, Liangliang Cheng, Kangsheng Tu, Xingfa Gao, Cui Liu, Mingzhen Zhang, Kelong Fan, Dai-Wen Pang, Xiyun Yan, 2023
  • Red Emissive Carbon Dot Superoxide Dismutase Nanozyme for Bioimaging and Ameliorating Acute Lung Injury, Liu, Cui, Fan, Wenbin, Cheng, WenXiang, Gu, Yiping, Chen, Yiming, Zhou, Wenhua, Yu, XueFeng, Chen, Minghai, Zhu, Minrong, Fan, Kelong, Luo, QingYing, 2023
  • A Thrombin-Activated Peptide-Templated Nanozyme for Remedying Ischemic Stroke via Thrombolytic and Neuroprotective Actions, Wang, Zhuoran, Zhao, Yue, Hou, Yaxin, Tang, Guoheng, Zhang, Ruofei, Yang, Yili, Yan, Xiyun, Fan, Kelong, 2023
  • 铁蛋白:疫苗设计新平台, 谢佳颖, 金奕良, 范克龙, 2022
  • Constructing a nanocage-based universal carrier for delivering TLR- activating nucleic acids to enhance antitumor immunotherapy, Zhang, Baoli, Chen, Xuehui, Tang, Guoheng, Zhang, Ruofei, Li, Jingyun, Sun, Guoming, Yan, Xiyun, Fan, Kelong, 2022
  • Ferritin-Nanocaged ATP Traverses the Blood-Testis Barrier and Enhances Sperm Motility in an Asthenozoospermia Model, Pang, Jing, Feng, Xu, Liang, Qian, Zheng, Xiaoyan, Duan, Yiman, Zhang, Xin, Zhang, Jubiao, Chen, Yang, Fan, Kelong, Gao, Lizeng, Li, Juxue, 2022
  • Ferritin nanocages for early theranostics of tumors via inflammation-enhanced active targeting, Jiang, Bing, Jia, Xiaohua, Ji, Tianjiao, Zhou, Meng, He, Jiuyang, Wang, Kun, Tian, Jie, Yan, Xiyun, Fan, Kelong, 2022
  • Edge-Site Engineering of Defective Fe-N-4 Nanozymes with Boosted Catalase-Like Performance for Retinal Vasculopathies, Zhang, Ruofei, Xue, Bai, Tao, Yanhong, Zhao, Hanqing, Zhang, Zixia, Wang, Xiaonan, Zhou, Xinyao, Jiang, Bing, Yang, Zhenglin, Yan, Xiyun, Fan, Kelong, 2022
  • H2O2 Self-Producing Single-Atom Nanozyme Hydrogels as Light-Controlled Oxidative Stress Amplifier for Enhanced Synergistic Therapy by Transforming 'Cold' Tumors, Zhu, Daoming, Chen, Hao, Huang, Chunyu, Li, Guoxin, Wang, Xing, Jiang, Wei, Fan, Kelong, 2022
  • Nanozyme: A promising tool from clinical diagnosis and environmental monitoring to wastewater treatment, Hong, Chaoyi, Meng, Xiangqin, He, Jiuyang, Fan, Kelong, Yan, Xiyun, 2022
  • 生物活性纳米材料用于重大疾病治疗的研究进展, 范克龙, 魏辉, 许华平, 王树涛, 曲晓刚, 张灿, 2022
  • Nanozyme-Based Artificial Organelles: An Emerging Direction for Artificial Organelles, Zhang, Shuai, Zhang, Ruofei, Yan, Xiyun, Fan, Kelong, 2022
  • High-Performance Self-Cascade Pyrite Nanozymes for Apoptosis-Ferroptosis Synergistic Tumor Therapy, Meng, Xiangqin, Li, Dandan, Chen, Lei, He, Helen, Wang, Qian, Hong, Chaoyi, He, Jiuyang, Gao, Xingfa, Yang, Yili, Jiang, Bing, Nie, Guohui, Yan, Xiyun, Gao, Lizeng, Fan, Kelong, 2021
  • A Nanozyme-Based Artificial Peroxisome Ameliorates Hyperuricemia and Ischemic Stroke, Xi, Juqun, Zhang, Ruofei, Wang, Liming, Xu, Wei, Liang, Qian, Li, Jingyun, Jiang, Jian, Yang, Yili, Yan, Xiyun, Fan, Kelong, Gao, Lizeng, 2021
  • In Vivo Regenerable Cerium Oxide Nanozyme-Loaded pH/H2O2-Responsive Nanovesicle for Tumor-Targeted Photothermal and Photodynamic Therapies, Zeng, Li, Cheng, Hui, Dai, Yuwei, Su, Zhipeng, Wang, Chengde, Lei, Lei, Lin, Deqing, Li, Xingyi, Chen, Hao, Fan, Kelong, Shi, Shuai, 2021
  • Low-cooling-rate freezing in biomolecular cryo-electron microscopy for recovery of initial frames, Wu, Chunling, Shi, Huigang, Zhu, Dongjie, Fan, Kelong, Zhang, Xinzheng, 2021
  • TiO2 supported single Ag atoms nanozyme for elimination of SARS-CoV2, Wang, Daji, Zhang, Bin, Ding, Hui, Liu, Dan, Xiang, Jianquan, Gao, Xuejiao J, Chen, Xuehui, Li, Zhongjun, Yang, Lei, Duan, Hongxia, Zheng, Jiyan, Liu, Zheng, Jiang, Bing, Liu, Yang, Xie, Ni, Zhang, Han, Yan, Xiyun, Fan, Kelong, Nie, Guohui, 2021
  • 铁蛋白装
Nanozymes Biomimetic Design Enzymes Catalysis Ferritin Drug Delivery Tumor Diagnosis Therapeutics Biomedical

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