1996-09--2001-08 Ph.D.: Institute of Biochemistry, Chinese Academy of Sciences
1992-08--1996-08 Bachelor's Degree in Science: Nanjing University
2007-12~Present - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Researcher
2002-10~2007-11 - University of Wisconsin-Madison, USA - Scientist/Postdoctoral
2001-12~2002-09 - University of Tennessee Health Science Center, USA - Postdoctoral
2001-09~2001-11 - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Assistant Researcher
1996-09~2001-08 - Institute of Biochemistry, Chinese Academy of Sciences - Ph.D. Student
1992-08~1996-08 - Nanjing University - Bachelor's Degree Student
Research
Regulation of tumor occurrence and metastasis by the cellular microenvironment
ZBTB7B is a permissive regulator of hepatocellular carcinoma initiation by repressing c-Jun expression and function, Gaoxiang Ge, 2024
LRP12 is an endogenous transmembrane inactivator of α4 integrins, Gaoxiang Ge, 2023
Lymphocyte integrins mediate entry and dysregulation of T cells by SARS-CoV-2, Gaoxiang Ge, 2023
Intact regulation of G1/S transition renders esophageal squamous cell carcinoma sensitive to PI3Kα inhibitors, Gaoxiang Ge, 2023
Exploring the underlying biology of cancer and potential therapeutic strategies: a special issue focused on mechanism-based studies, Gaoxiang Ge, 2023
Type IV collagen α5 chain promotes luminal breast cancer progression through c-Myc-driven glycolysis, Gaoxiang Ge, 2023
Autocrine pro-legumain promotes breast cancer metastasis via binding to integrin αvβ3, Gaoxiang Ge, 2022
Basement membrane promotes tumor development by attenuating T cell activation, Gaoxiang Ge, 2022
Integrin αEβ7 + T cells direct intestinal stem cell fate decisions via adhesion signaling, Gaoxiang Ge, 2021
Perivenous Stellate Cells Are the Main Source of Myofibroblasts and Cancer-Associated Fibroblasts Formed After Chronic Liver Injuries, Gaoxiang Ge, 2021
A mutation that blocks integrin alpha(4)beta(7) activation prevents adaptive immune-mediated colitis without increasing susceptibility to innate colitis, Gaoxiang Ge, 2020
The micropeptide LEMP plays an evolutionarily conserved role in myogenesis, Gaoxiang Ge, 2020
Progress of Extracellular Matrix., Gaoxiang Ge, 2019
Protein C receptor is a therapeutic stem cell target in a distinct group of breast cancers, Gaoxiang Ge, 2019
Dual function of VGLL 4 in muscle regeneration, Gaoxiang Ge, 2019
Complexity of type IV collagens: from network assembly to function, Gaoxiang Ge, 2019
Fever Promotes T Lymphocyte Trafficking via a Thermal Sensory Pathway Involving Heat Shock Protein 90 and α4 Integrins., Gaoxiang Ge, 2018
FSP1-positive fibroblasts are adipogenic niche and regulate adipose homeostasis, Gaoxiang Ge, 2018
Integrin α4β7 switches its ligand specificity via distinct conformer-specific activation, Gaoxiang Ge, 2018
细胞外基质与肿瘤相关成纤维细, Gaoxiang Ge, 2017
Minor Type IV Collagen α5 Chain Promotes Cancer Progression through Discoidin Domain Receptor-1., Gaoxiang Ge, 2015
C/EBP Mediates TNF--Induced Cancer Cell Migration by Inducing MMP Expression Dependent on p38 MAPK, Gaoxiang Ge, 2015
Targeting type I. phosphatidylinositol phosphate kinase inhibits breast cancer metastasis, Gaoxiang Ge, 2015
Transdifferentiation of lung adenocarcinoma in mice with Lkb1 deficiency to squamous cell carcinoma, Gaoxiang Ge, 2014
Snail and Slug mediate tamoxifen resistance in breast cancer cells through activation of EGFR-ERK independent of epithelial-mesenchymal transition, Gaoxiang Ge, 2014
Activator protein 1 suppresses antitumor T-cell function via the induction of programmed death 1, Gaoxiang Ge, 2012
Lysyl Oxidase, Extracellular Matrix Remodeling and Cancer Metastasis, Gaoxiang Ge, 2012
LKB1 in lung cancerigenesis: a serine/threonine kinase as tumor suppressor, Gaoxiang Ge, 2011
The CC and DE loops in Ig domains 1 and 2 of MAdCAM-1 play different roles in MAdCAM-1 binding to low- and high-affinity integrin a4b7., Gaoxiang Ge, 2011
α3(V) Collagen is critical for glucose homeostasis in mice due to effects in pancreatic islets and peripheral tissues, Gaoxiang Ge, 2011
LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling, Gaoxiang Ge, 2010
Fibronectin Binds and Enhances the Activity of Bone Morphogenetic Protein 1, Gaoxiang Ge, 2009
Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction, Gaoxiang Ge, 2009
ADAMTSL2 mutations in geleophysic dysplasia demonstrate a role for ADAMTS-like proteins in TGF-beta bioavailability regulation, Gaoxiang Ge, 2008
BIOCHEM BIOPHYS RES COMMUN, Gaoxiang Ge, 2008
Bone Morphogenetic Protein 1 Processes Prolactin to a 17kDa Anti-Angiogenic Form., Gaoxiang Ge, 2007
Bone Morphogenetic Protein 1 Prodomain Specifically Binds, Localizes and Regulates Signaling of Bone Morphogenetic Proteins 2 and 4., Gaoxiang Ge, 2007
CANCER INFORMATICS, Gaoxiang Ge, 2006
Developmental roles of the BMP1/TLD metalloproteinases., Gaoxiang Ge, 2006
bmp1 and mini fin are functionally redundant in regulating formation of the zebrafish dorsoventral axis, Gaoxiang Ge, 2006
Mammalian Tolloid-like 1 Binds Procollagen C-proteinase Enhancer Protein 1 and Differs from Bone Morphogenetic Protein 1 in the Functional Roles of Homologous Protein Domains, Gaoxiang Ge, 2006
TIMP-3 inhibits the procollagen N-proteinase ADAMTS-2, Gaoxiang Ge, 2006
Inhibition of Bone Morphogenetic Protein 1 by Native and Altered Forms of α2-Macroglobulin, Gaoxiang Ge, 2006
GDF11 Forms a Bone Morphogenetic Protein 1-Activated Latent Complex That Can Modulate Nerve Growth Factor-Induced Differentiation of PC12 Cells, Gaoxiang Ge, 2005
Bone morphogenetic protein-1/Tolloid-related metalloproteinases process osteoglycin and enhance its ability to regulate collagen fibrillogenesis, Gaoxiang Ge, 2004
Area of Focus
Epigenetics | Embryonic Development | Cell Fate | Cancer | Metastasis | Drug Resistance | Gene Expression | Dna Methylation | Histone Modification | Chromatin Structure
