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Aike Guo
Life Science
University of Chinese Academy of Sciences
Shanghai
Language: Chinese, English, German
Cognition
Neurobiology
Behavior
Neural Circuits
Memory
Learning
Drosophila
Synaptic Strength
Olfactory Processing
Gaba System
Areas of Focus
- Cognitive Neurobiology
- Neuroethology
- Neuroconnectomics
Work Experience
- 1988 - Present - Researcher at Institute of Biophysics, Chinese Academy of Sciences
- 1999 - Present - Senior Researcher at Institute of Neuroscience, Chinese Academy of Sciences
- 1982-11-30 to 1984-06-30 - Visiting Scholar at Max Planck Institute for Biological Cybernetics
- 1984 to 1991 - Director of Visual Information Processing Laboratory, Institute of Biophysics, Chinese Academy of Sciences
- 1991 to 1995 - Director of Neurobiology Laboratory, Institute of Biophysics, Chinese Academy of Sciences
- 1999-11 to Present - Senior Researcher at Learning and Memory Laboratory, Institute of Neuroscience, Chinese Academy of Sciences
- 2005 to Present - Chairman of Academic Committee, State Key Laboratory of Brain and Cognitive Science
- 2003 to 2008 - Deputy Director, Institute of Neuroscience, Chinese Academy of Sciences
- 1999 to 2001 - Director, Asia-Pacific IBRO
- 2001 to Present - Editorial Board Member, Journal of Integrative Neuroscience
- 2008 to Present - Associate Editor, BMC Neuroscience
Academic Background & Achievements
- 1965 - Graduated in Biophysics from Moscow University
- 1979 - PhD in Natural Sciences from Munich University
Publications
- Astrocyte-like glial cells physiologically regulate olfactory processing through the modification of ORN-PN synaptic strength in Drosophila, Liu, H., Zhou, B., Yan, W., Lei, Z., Zhao, X., Zhang, K., and Guo, A., 2014
- The GABA system regulates the sparse coding of odors in the mushroom bodies of Drosophila, Lei, Z., Chen, K., Li, H., Liu, H., and Guo, A., 2013
- Transformation of odor selectivity from projection neurons to single mushroom body neurons mapped with dual-color calcium imaging, Li, H., Li, Y., Lei, Z., Wang, K., and Guo, A., 2013
- Distinct acute zones for visual stimuli in different visual tasks in Drosophila, Yang, X., and Guo, A., 2013
- The GABAergic anterior paired lateral neurons facilitate olfactory reversal learning in Drosophila, Wu, Y., Ren, Q., Li, H., and Guo, A., 2012
- A gabaergic inhibitory neural circuit regulates visual reversal learning in drosophila, Ren, Q., Li, H., Wu, Y., Ren, J., and Guo, A., 2012
- Mutation of Drosophila dopamine receptor DopR leads to male-male courtship behavior, Chen, B., Liu, H., Ren, J., and Guo, A., 2012
- Sleep Deprivation Specifically Impairs Short-term Olfactory Memory in Drosophila, Li, X., Yu, F., and Guo, A., 2009
- Reduction of dopamine level enhances the attractiveness of male Drosophila to other males, Liu, T., Dartevelle, L., Yuan, C., Wei, H., Wang, Y., Ferveur, J, and Guo, A., 2009
- Impact of network topology on decision-making, Lu, S., Fang, J., Guo, A., and Peng, Y., 2009
- Increased dopamine level enhances male-male courtship in Drosophila, Liu, T., Dartevelle, L., Yuan, C., Wei, H., Wang, Y., Ferveur J., and Guo, A., 2008
- Mushroom bodies modulate salience-based selective fixation behavior in Drosophila, Xi, W., Peng, Y., Guo, J., Ye, Y., Zhang, K., Yu, F., and Guo, A., 2008
- Dopamine-Mushroom Body Circuit Regulates Saliency-Based Decision-Making in Drosophila, Zhang, K., Guo, J., Peng, Y., Xi, W., and Guo, A., 2007
- Experience Improves Feature Extraction in Drosophila, Peng, Y., Xi, W., Zhang, W., Zhang, K., and Guo, A., 2007
- Thermal nociception in adult Drosophila: behavioral characterization and the role of the painless gene, Xu, S., Cang, C., Liu, X., Peng, Y., Ye, Y., Zhao, Z., and Guo, A., 2006
- Crossmodal Interactions Between Olfactory and Visual Learning in Drosophila, Guo, J., and Guo, A., 2005
- Drosophila Olfactory Response Rhythms Require Clock Genes but Not Pigment Dispersing Factor or Lateral Neurons, Zhou, X., Yuan, C., and Guo, A., 2005
- Long-term but not short-term blockade of dopamine release in Drosophila impairs orientation during flight in a visual attention paradigm, Ye, Y., Xi, W., Peng, Y., Wang, Y., and Guo, A., 2004
- Choice behavior of Drosophila facing contradictory visual cues, Tang, S., and Guo, A., 2001
Awards
- 2006 - Ho Leung Ho Lee Foundation Science and Technology Progress Award
- 2008 - Asia-Pacific Neural Network Society Outstanding Achievement Award
