Professor | Gao Daming | Asia Growth Partners

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Name	Gao Daming
Contact Information	dgao@sibcb.ac.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Gao Daming

Contact Information

dgao@sibcb.ac.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2001-09 to 2006-07 Ph.D.: Shanghai Institute of Life Sciences, Chinese Academy of Sciences 1997-09 to 2001-07 Bachelor's: Shandong University
Work Experience	2012-07 to Present - Shanghai Institute of Life Sciences, Chinese Academy of Sciences - Researcher 2010-08 to 2012-07 - Beth Israel Deaconess Medical Center, Harvard Medical School - Lecturer 2006-12 to 2010-07 - Beth Israel Deaconess Medical Center, Harvard Medical School - Postdoctoral Fellow

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2001-09 to 2006-07 Ph.D.: Shanghai Institute of Life Sciences, Chinese Academy of Sciences
1997-09 to 2001-07 Bachelor's: Shandong University

Work Experience

2012-07 to Present - Shanghai Institute of Life Sciences, Chinese Academy of Sciences - Researcher
2010-08 to 2012-07 - Beth Israel Deaconess Medical Center, Harvard Medical School - Lecturer
2006-12 to 2010-07 - Beth Israel Deaconess Medical Center, Harvard Medical School - Postdoctoral Fellow

Areas of Focus	Cancer Signal Transduction and Metabolism
Publications	Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies, 27th Author, 2024 Identification of XAF1 as an endogenous AKT inhibitor, 22nd Author, 2023 Tumor-immune microenvironment and NRF2 associate with clinical efficacy of PD-1 blockade combined with chemotherapy in lung squamous cell carcinoma, 20th Author, 2023 Exploring the underlying biology of cancer and potential therapeutic strategies: a special issue focused on mechanism-based studies, 11th Author, 2023 CUL4B-DDB1-COP1-mediated UTX downregulation promotes colorectal cancer progression, 11th Author, 2023 Proteogenomic characterization identifies clinically relevant subgroups of intrahepatic cholangiocarcinoma, 11th Author, 2022 Multimodule characterization of immune subgroups in intrahepatic cholangiocarcinoma reveals distinct therapeutic vulnerabilities, 11th Author, 2022 CUL5-ASB6 Complex Promotes p62/SQSTM1 Ubiquitination and Degradation to Regulate Cell Proliferation and Autophagy, 2nd Author, 2021 Osteomodulin positively regulates osteogenesis through interaction with BMP2, 5th Author, 2021 SCF FBXW7/GSK3β-Mediated GFI1 Degradation Suppresses Proliferation of Gastric Cancer Cells, 11th Author, 2019 Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma, 11th Author, 2019 Cullin5 deficiency promotes small-cell lung cancer metastasis by stabilizing integrin beta 1, 11th Author, 2019 Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics, 6th Author, 2019 CUL5-SOCS6 complex regulates mTORC2 function by targeting Sin1 for degradation, 11th Author, 2019 The mtor-s6k pathway links growth signalling to dna damage response by targeting rnf168, 11th Author, 2018 A novel USP9X substrate TTK contributes to tumorigenesis in non-small-cell lung cancer., 13th Author, 2018 Extracellular Signal-regulated Kinases (ERKs) Phosphorylate Lin28aProtein to Modulate P19 Cell Proliferation and Differentiation, 6th Author, 2017 Acetylation of PGK1 Promotes Liver Cancer Cell Proliferation and Tumorigenesis, 11th Author, 2017 Acetylation-Dependent Regulation of Skp2 Function, 2nd Author, 2012 mTOR drives its own activation via SCFb-TRCP-dependent degradation of the mTOR inhibitor DEPTOR, 1st Author, 2011 Rictor Forms a Complex with Cullin-1 to Promote SGK1 Ubiquitination and Destruction, 1st Author, 2010 Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APC/Cdh1-mediated Skp2 destruction, 1st Author, 2009 Cdh1 Regulates Cell Cycle through Modulating the Claspin/Chk1 and the Rb/E2F1 Pathways, 1st Author, 2009

Areas of Focus

Cancer Signal Transduction and Metabolism

Publications

Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies, 27th Author, 2024
Identification of XAF1 as an endogenous AKT inhibitor, 22nd Author, 2023
Tumor-immune microenvironment and NRF2 associate with clinical efficacy of PD-1 blockade combined with chemotherapy in lung squamous cell carcinoma, 20th Author, 2023
Exploring the underlying biology of cancer and potential therapeutic strategies: a special issue focused on mechanism-based studies, 11th Author, 2023
CUL4B-DDB1-COP1-mediated UTX downregulation promotes colorectal cancer progression, 11th Author, 2023
Proteogenomic characterization identifies clinically relevant subgroups of intrahepatic cholangiocarcinoma, 11th Author, 2022
Multimodule characterization of immune subgroups in intrahepatic cholangiocarcinoma reveals distinct therapeutic vulnerabilities, 11th Author, 2022
CUL5-ASB6 Complex Promotes p62/SQSTM1 Ubiquitination and Degradation to Regulate Cell Proliferation and Autophagy, 2nd Author, 2021
Osteomodulin positively regulates osteogenesis through interaction with BMP2, 5th Author, 2021
SCF FBXW7/GSK3β-Mediated GFI1 Degradation Suppresses Proliferation of Gastric Cancer Cells, 11th Author, 2019
Integrated Proteogenomic Characterization of HBV-Related Hepatocellular Carcinoma, 11th Author, 2019
Cullin5 deficiency promotes small-cell lung cancer metastasis by stabilizing integrin beta 1, 11th Author, 2019
Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics, 6th Author, 2019
CUL5-SOCS6 complex regulates mTORC2 function by targeting Sin1 for degradation, 11th Author, 2019
The mtor-s6k pathway links growth signalling to dna damage response by targeting rnf168, 11th Author, 2018
A novel USP9X substrate TTK contributes to tumorigenesis in non-small-cell lung cancer., 13th Author, 2018
Extracellular Signal-regulated Kinases (ERKs) Phosphorylate Lin28aProtein to Modulate P19 Cell Proliferation and Differentiation, 6th Author, 2017
Acetylation of PGK1 Promotes Liver Cancer Cell Proliferation and Tumorigenesis, 11th Author, 2017
Acetylation-Dependent Regulation of Skp2 Function, 2nd Author, 2012
mTOR drives its own activation via SCFb-TRCP-dependent degradation of the mTOR inhibitor DEPTOR, 1st Author, 2011
Rictor Forms a Complex with Cullin-1 to Promote SGK1 Ubiquitination and Destruction, 1st Author, 2010
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APC/Cdh1-mediated Skp2 destruction, 1st Author, 2009
Cdh1 Regulates Cell Cycle through Modulating the Claspin/Chk1 and the Rb/E2F1 Pathways, 1st Author, 2009

Cancer Signal Transduction Metabolism Tumor Cell Biology Biochemistry Molecular Biology Therapeutic Strategies Oncology Research

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