Creatine promotes cancer metastasis through activation of Smad2/3, Liwen Zhang, Zijing Zhu, Huiwen Yan, Wen Wang, Zhenzhen Wu, Fei Zhang, Qixiang Zhang, Guizhi Shi, Junfeng Du, Huiyun Cai, Xuanxuan Zhang, David Hsu, Pu Gao, Hailong Piao, Gang Chen, Pengcheng Bu, 2021
Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome, Chen Shen, Runzhi Li, Roberto Negro, Jiewei Cheng, Setu M Vora, TianMin Fu, Anmin Wang, Kaixin He, Liudmila Andreeva, Pu Gao, Zhigang Tian, Richard A Flavell, Shu Zhu, Hao Wu, 2021
Interferon-armed RBD dimer enhances the immunogenicity of RBD for sterilizing immunity against SARS-CoV-2, Shiyu Sun, Yueqi Cai, TianZhang Song, Yang Pu, Lin Cheng, Hairong Xu, Jing Sun, Chaoyang Meng, Yifan Lin, Haibin Huang, Fang Zhao, Silin Zhang, Yu Gao, JianBao Han, XiaoLi Feng, DanDan Yu, Yalan Zhu, Pu Gao, Haidong Tang, Jincun Zhao, Zheng Zhang, Jiaming Yang, Zhenxiang Hu, YangXin Fu, YongTang Zheng, Hua Peng, 2021
Structural insights into assembly, operation and inhibition of a type I restriction-modification system, Yina Gao, Duanfang Cao, Jingpeng Zhu, Han Feng, Xiu Luo, Songqing Liu, XiaoXue Yan, Xinzheng Zhang, Pu Gao, 2020
Molecular Mechanism of RNA Recognition by Zinc-Finger Antiviral Protein, Xiu Luo, Xinlu Wang, Yina Gao, Jingpeng Zhu, Songqing Liu, Guangxia Gao, Pu Gao, 2020
Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10, Han Feng, Huabin Tian, Yong Wang, Qixiang Zhang, Ni Lin, Songqing Liu, Yang Yu, Hongyu Deng, Pu Gao, 2020
Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors, Yong Wang, Qi Zhan, Xinlu Wang, Peipei Li, Songqing Liu, Guangxia Gao, Pu Gao, 2020
Diverse Mechanisms of CRISPR-Cas9 Inhibition by Type IIC Anti-CRISPR Proteins, Yalan Zhu, Ang Gao, Qi Zhan, Yong Wang, Han Feng, Songqing Liu, Guangxia Gao, Alexander Serganov, Pu Gao, 2019
Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression, Lodoe Lama, Carolina Adura, Wei Xie, Daisuke Tomita, Taku Kamei, Vitaly Kuryavyi, Tasos Gogakos, Joshua I Steinberg, Michael Miller, Lavoisier RamosEspiritu, Yasutomi Asano, Shogo Hashizume, Jumpei Aida, Toshihiro Imaeda, Rei Okamoto, Andy J Jennings, Mayako Michino, Takanobu Kuroita, Andrew Stamford, Pu Gao, Peter Meinke, J Fraser Glickman, Dinshaw J Patel, Thomas Tuschl, 2019
Regulation of HIV-1 Gag-Pol Expression by Shiftless, an Inhibitor of Programmed −1 Ribosomal Frameshifting, Xinlu Wang, Yifang Xuan, Yuling Han, Xiang Ding, Kai Ye, Fuquan Yang, Pu Gao, Stephen P Goff, Guangxia Gao, 2019
Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE, Yong Wang, Miao Shi, Han Feng, Yalan Zhu, Songqing Liu, Ang Gao, Pu Gao, 2018
Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice, Jessica Vincent, Carolina Adura, Pu Gao, Antonio Luz, Lodoe Lama, Yasutomi Asano, Rei Okamoto, Toshihiro Imaeda, Jumpei Aida, Katherine Rothamel, Tasos Gogakos, Joshua Steinberg, Seth Reasoner, Kazuyoshi Aso, Thomas Tuschl, Dinshaw J Patel, J Fraser Glickman, Manuel Ascano, 2017
Structural basis underlying complex assembly and conformational transition of the type I R-M system, YanPing Liu, Qun Tang, JieZhong Zhang, LiFei Tian, Pu Gao, XiaoXue Yan, 2017
Structural insights into glutathione-mediated activation of the master regulator PrfA in Listeria monocytogenes, Yong Wang, Han Feng, Yalan Zhu, Pu Gao, 2017
Pistol ribozyme adopts a pseudoknot fold facilitating site-specific in-line cleavage, Aiming Ren, Nikola Vusurovic, Jennifer Gebetsberger, Pu Gao, Michael Juen, Christoph Kreutz, Ronald Micura, Dinshaw J Patel, 2016
PAM-Dependent Target DNA Recognition and Cleavage by C2c1 CRISPR-Cas Endonuclease, Hui Yang, Pu Gao, Kanagalaghatta R Rajashankar, Dinshaw J Patel, 2016
DNA sensor cGAS-mediated immune recognition, Pengyan Xia, Shuo Wang, Pu Gao, Guangxia Gao, Zusen Fan, 2016
Type V CRISPR-Cas Cpf1 endonuclease employs a unique mechanism for crRNA-mediated target DNA recognition, Pu Gao, Hui Yang, Kanagalaghatta R Rajashankar, Zhiwei Huang, Dinshaw J Patel, 2016
V-cGAPs: attenuators of 3 ' 3 '-cGAMP signaling, Pu Gao, Thomas Zillinger, Weiyi Wang, Manuel Ascano, Peihong Dai, Gunther Hartmann, Thomas Tuschl, Liang Deng, Winfried Barchet, Dinshaw J Patel, 2015
Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA, Pu Gao, Manuel Ascano, Thomas Zillinger, Weiyi Wang, Peihong Dai, Artem A Serganov, Barbara L Gaffney, Stewart Shuman, Roger A Jones, Liang Deng, Gunther Hartmann, Winfried Barchet, Thomas Tuschl, Dinshaw J Patel, 2014
Structure-Function Analysis of STING Activation by cG(2 ',5 ') pA(3 ',5 ')p and Targeting by Antiviral DMXAA, Pu Gao, Manuel Ascano, Thomas Zillinger, Weiyi Wang, Peihong Dai, Artem A Serganov, Barbara L Gaffney, Stewart Shuman, Roger A Jones, Liang Deng, Gunther Hartmann, Winfried Barchet, Thomas Tuschl, Dinshaw J Patel, 2013
SMARCA3, a chromation-remodeling factor, is required for p11-dependent antidepressant action, Pu Gao, 2013
Cyclic G(2 ',5 ') pA(3 ',5 ')p Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase, Pu Gao, Manuel Ascano, Yang Wu, Winfried Barchet, Barbara L Gaffney, Thomas Zillinger, Artem A Serganov, Yizhou Liu, Roger A Jones, Gunther Hartmann, Thomas Tuschl, Dinshaw J Patel, 2013
RecOR complex including RecR N-N dimer and RecO monomer displays a high affinity for ssDNA, Qun Tang, Pu Gao, YanPing Liu, Ang Gao, XiaoMin An, Sh
