Professor | Fuhong He | Asia Growth Partners

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Name	Fuhong He
Contact Information	hefh@big.ac.cn
Language ability	Chinese, English
Province	Beijing

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Name

Fuhong He

Contact Information

hefh@big.ac.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2004-09--2009-06 PhD: Beijing Institute of Genomics, Chinese Academy of Sciences 2000-09--2004-06 Bachelor's Degree: Anhui University
Work Experience	2020-06~Present - Beijing Institute of Genomics, Chinese Academy of Sciences - Master's Supervisor 2019-07~Present - Beijing Institute of Genomics, Chinese Academy of Sciences - Associate Researcher 2015-01~2019-06 - Beijing Institute of Genomics, Chinese Academy of Sciences - Associate Researcher 2009-07~2014-12 - Beijing Institute of Genomics, Chinese Academy of Sciences - Assistant Researcher
Awards	Central and State Organs 'Four Strong' Party Branch (2022): National Level Outstanding Party Worker of Beijing Institute of Genomics, Chinese Academy of Sciences (2021): Institute Level 62nd American Society of Hematology Annual Meeting Abstract Achievement Award (2020): Other 60th American Society of Hematology Annual Meeting Abstract Achievement Award (2018): Other First Prize in Poster Selection at the 2nd Genomic Medicine Frontier and Health Benefit Forum and Annual Meeting of the Precision Laboratory of the Institute of Genomics, Chinese Academy of Sciences (2018): Institute Level 58th American Society of Hematology Annual Meeting Abstract Achievement Award (2016): Other Member of the Youth Innovation Promotion Association of the Chinese Academy of Sciences (2015): Institute Level

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2004-09--2009-06 PhD: Beijing Institute of Genomics, Chinese Academy of Sciences
2000-09--2004-06 Bachelor's Degree: Anhui University

Work Experience

2020-06~Present - Beijing Institute of Genomics, Chinese Academy of Sciences - Master's Supervisor
2019-07~Present - Beijing Institute of Genomics, Chinese Academy of Sciences - Associate Researcher
2015-01~2019-06 - Beijing Institute of Genomics, Chinese Academy of Sciences - Associate Researcher
2009-07~2014-12 - Beijing Institute of Genomics, Chinese Academy of Sciences - Assistant Researcher

Awards

Central and State Organs 'Four Strong' Party Branch (2022): National Level
Outstanding Party Worker of Beijing Institute of Genomics, Chinese Academy of Sciences (2021): Institute Level
62nd American Society of Hematology Annual Meeting Abstract Achievement Award (2020): Other
60th American Society of Hematology Annual Meeting Abstract Achievement Award (2018): Other
First Prize in Poster Selection at the 2nd Genomic Medicine Frontier and Health Benefit Forum and Annual Meeting of the Precision Laboratory of the Institute of Genomics, Chinese Academy of Sciences (2018): Institute Level
58th American Society of Hematology Annual Meeting Abstract Achievement Award (2016): Other
Member of the Youth Innovation Promotion Association of the Chinese Academy of Sciences (2015): Institute Level

Areas of Focus	Genomics of Hematologic Tumors and Precision Medicine
Publications	Single-cell transcriptomics reveals multiple chemoresistant properties in leukemic stem and progenitor cells in pediatric AML, Fuhong He, 2023 Identification of Chemo-Resistant Residual Cell Population in Pediatric AML of Complete Remission By Single Cell RNA Sequencing, Fuhong He, 2020 Benzene metabolite hydroquinone promotes DNA homologous recombination repair via the NF-kappa B pathway, Fuhong He, 2019 Ecological principle meets cancer treatment: treating children with acute myeloid leukemia with low-dose chemotherapy, Fuhong He, 2019 Cooperative Epigenetic Regulation By ASXL1 and NF1 Loss on Leukemogenesis, Fuhong He, 2018 Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy, Fuhong He, 2018 SETD2-mediated crosstalk between H3K36me3 and H3K79me2 in MLL-rearranged leukemia, Fuhong He, 2018 PDGFRB mutation and tyrosine kinase inhibitor resistance in Ph-like acute lymphoblastic leukemia, Fuhong He, 2018 Loss of Asxl2 leads to myeloid malignancies in mice, Fuhong He, 2017 Loss of Asxl1 Alters Self-Renewal and Cell Fate of Bone Marrow Stromal Cells, Leading to Bohring-Opitz-like Syndrome in Mice, Fuhong He, 2016 ASXL2 Is Required for Normal Hematopoiesis and Loss of asxl2 Leads to Myeloid Malignancies in Mice, Fuhong He, 2016 组蛋白去甲基化酶LSD1抑制剂对MLL-ENL白血病细胞诱导分化的研究, Fuhong He, 2015 PU.1 is essential for MLL leukemia partially via crosstalk with the MEIS/HOX pathway, Fuhong He, 2014 Identification of functional cooperative mutations of SETD2 in human acute leukemia, Fuhong He, 2014 Downregulation of RUNX1/CBF beta by MLL fusion proteins enhances hematopoietic stem cell self-renewal, Fuhong He, 2014 Regulation of MEIS1 by distal enhancer elements in acute leukemia., Fuhong He, 2014 Rictor/mammalian target of rapamycin 2 regulates the development of notch1 induced murine T-cell acute lymphoblastic leukemia via forkhead box O3, Fuhong He, 2014 Reprogramming of MLL-AF9 leukemia cells into pluripotent stem cells, Fuhong He, 2014 Gene and Genome Parameters of Mammalian Liver Circadian Genes (LCGs), Fuhong He, 2012 MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genome, Fuhong He, 2011 A Novel Role for Minimal Introns: Routing mRNAs to the Cytosol, Fuhong He, 2010 How Do Variable Substitution Rates Influence Ka and Ks Calculations?, Fuhong He, 2009 On the nature of human housekeeping genes, Fuhong He, 2008 How many human genes can be defined as housekeeping with current expression data?, Fuhong He, 2008 Modeling Transcriptome Based on Transcript-Sampling Data, Fuhong He, 2008

Areas of Focus

Genomics of Hematologic Tumors and Precision Medicine

Publications

Single-cell transcriptomics reveals multiple chemoresistant properties in leukemic stem and progenitor cells in pediatric AML, Fuhong He, 2023
Identification of Chemo-Resistant Residual Cell Population in Pediatric AML of Complete Remission By Single Cell RNA Sequencing, Fuhong He, 2020
Benzene metabolite hydroquinone promotes DNA homologous recombination repair via the NF-kappa B pathway, Fuhong He, 2019
Ecological principle meets cancer treatment: treating children with acute myeloid leukemia with low-dose chemotherapy, Fuhong He, 2019
Cooperative Epigenetic Regulation By ASXL1 and NF1 Loss on Leukemogenesis, Fuhong He, 2018
Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy, Fuhong He, 2018
SETD2-mediated crosstalk between H3K36me3 and H3K79me2 in MLL-rearranged leukemia, Fuhong He, 2018
PDGFRB mutation and tyrosine kinase inhibitor resistance in Ph-like acute lymphoblastic leukemia, Fuhong He, 2018
Loss of Asxl2 leads to myeloid malignancies in mice, Fuhong He, 2017
Loss of Asxl1 Alters Self-Renewal and Cell Fate of Bone Marrow Stromal Cells, Leading to Bohring-Opitz-like Syndrome in Mice, Fuhong He, 2016
ASXL2 Is Required for Normal Hematopoiesis and Loss of asxl2 Leads to Myeloid Malignancies in Mice, Fuhong He, 2016
组蛋白去甲基化酶LSD1抑制剂对MLL-ENL白血病细胞诱导分化的研究, Fuhong He, 2015
PU.1 is essential for MLL leukemia partially via crosstalk with the MEIS/HOX pathway, Fuhong He, 2014
Identification of functional cooperative mutations of SETD2 in human acute leukemia, Fuhong He, 2014
Downregulation of RUNX1/CBF beta by MLL fusion proteins enhances hematopoietic stem cell self-renewal, Fuhong He, 2014
Regulation of MEIS1 by distal enhancer elements in acute leukemia., Fuhong He, 2014
Rictor/mammalian target of rapamycin 2 regulates the development of notch1 induced murine T-cell acute lymphoblastic leukemia via forkhead box O3, Fuhong He, 2014
Reprogramming of MLL-AF9 leukemia cells into pluripotent stem cells, Fuhong He, 2014
Gene and Genome Parameters of Mammalian Liver Circadian Genes (LCGs), Fuhong He, 2012
MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genome, Fuhong He, 2011
A Novel Role for Minimal Introns: Routing mRNAs to the Cytosol, Fuhong He, 2010
How Do Variable Substitution Rates Influence Ka and Ks Calculations?, Fuhong He, 2009
On the nature of human housekeeping genes, Fuhong He, 2008
How many human genes can be defined as housekeeping with current expression data?, Fuhong He, 2008
Modeling Transcriptome Based on Transcript-Sampling Data, Fuhong He, 2008

Genomics Hematologic Tumors Precision Medicine Bioinformatics Cancer Leukemia Genetic Mutations Chemoresistance Single-Cell Transcriptomics Epigenetics

Qi Liu - Tongji University

Lu Dongdong - Tongji University

Chenfei Wang - Tongji University

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