Structures of the atlastin GTPase provide insight into homotypic fusion of endoplasmic reticulum membranes (2011): Selected as one of China's top 100 most internationally influential academic papers
Howard Hughes Medical Institute (HHMI) International Young Scientist Award (2012)
China Science News Agency Third 'Young Science Star' title (2012)
Tianjin Youth May Fourth Medal (2012)
National Natural Science Foundation of China Outstanding Youth Fund (2013)
Central Organization Department Youth Top Talent (2014)
Research
Morphology and function of the endoplasmic reticulum and other important organelles
Oligomeric scaffolding for curvature generation by ER tubule-forming proteins., Xiang Y, Lyu R, Hu J., 2023
Molecular basis of Climp63-mediated ER lumen spacing., Xu L, Xiang Y, Hu J., 2023
Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction., Guo Y, Zhang H, Yan C, Shen B, Zhang Y, Guo X, Sun S, Yu F, Yan J, Liu R, Zhang Q, Zhang D, Liu H, Liu Y, Zhang Y, Li W, Qin J, Lv H, Wang Z, Yuan Y, Yang JF, Zhong YT, Gao S, Zhou B, Liu L, Kong D, Hao X, Hu J, Chen Q., 2023
A SURF4-to-proteoglycan relay mechanism that mediates the sorting and secretion of a tagged variant of sonic hedgehog., Tang X, Chen R, Mesias VSD, Wang T, Wang Y, Poljak K, Fan X, Miao X, Hu J, Zhang L, Huang J, Yao S, Miller EA, Guo Y., 2022
Reconstitution of Fusion-Competent Human Placental Fusogen Syncytin-2., Xu L, Sun S., 2022
SARS-CoV-2 ORF8 reshapes the ER through forming mixed disulfides with ER oxidoreductases., Liu P, Wang X, Sun Y, Zhao H, Cheng F, Wang J, Yang F, Hu J, Zhang H, Wang CC, Wang L., 2022
DeepContact: High-throughput quantification of membrane contact sites based on electron microscopy imaging., Liu L, Yang S, Liu Y, Li X, Hu J, Xiao L, Xu T., 2022
Endoplasmic reticulum composition and form: Proteins in and out., Sun S, Tang X, Guo Y, Hu J., 2021
FIT2 organizes lipid droplet biogenesis with ER tubule-forming proteins and septins., Chen F, Yan B, Ren J, Lyu R, Wu Y, Guo Y, Li D, Zhang H, Hu J., 2021
Atlastin 2/3 regulate ER targeting of the ULK1 complex to initiate autophagy., Liu N, Zhao H, Zhao YG, Hu J, Zhang H., 2021
Coupling and Uncoupling: Dynamic Control of Membrane Contacts., Zhang D, Saheki Y, Kornmann B, Hu J, 2021
SNX27-FERM-SNX1 complex structure rationalizes divergent trafficking pathways by SNX17 and SNX27., Yong X, Zhao L, Hu W, Sun Q, Ham H, Liu Z, Ren J, Zhang Z, Zhou Y, Yang Q, Mo X, Hu J, Billadeau DD, Jia D., 2021
Structural analysis of a trimeric assembly of the mitochondrial dynamin-like GTPase Mgm1., Yan L, Qi Y, Ricketson D, Li L, Subramanian K, Zhao J, Yu C, Wu L, Sarsam R, Wong M, Lou Z, Rao Z, Nunnari J, Hu J., 2020
STIM1 interacts with termini of Orai channels in a sequential manner., Niu L, Wu F, Li K, Li J, Zhang SL, Hu J, Wang Q., 2020
Structural insights into G domain dimerization and pathogenic mutation of OPA1., Yu C, Zhao J, Yan L, Qi Y, Guo X, Lou Z, Hu J, Rao Z., 2020
A Plasmodium homolog of ER tubule-forming proteins is required for parasite virulence., Shi X, Hai L, Govindasamy K, Gao J, Coppens I, Hu J, Wang Q, Bhanot P., 2020
Self-Association of Purified Reconstituted ER Luminal Spacer Climp63, Zhao J and Hu J., 2020
At last in the physiological roles of the tubular ER network, Lv L, Niu L, Hu J., 2020
Mitochondrial Fusion: The Machineries In and Out., Gao S, Hu J., 2021
Atlastin-1 regulates morphology and function of endoplasmic reticulum in dendrites., Liu X, Guo X, Niu L, Li X, Sun F, Hu J, Wang X, Shen K., 2019
Atlastin-mediated membrane tethering is critical for cargo mobility and exit from the endoplasmic reticulum., Niu L, Ma T, Yang F, Yan B, Tang X, Yin H, Wu Q, Huang Y, Yao ZP, Wang J, Guo Y, Hu J., 2019
Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset., Li YJ, Cao YL, Feng JX, Qi Y, Meng S, Yang JF, Zhong YT, Kang S, Chen X, Lan L, Luo L, Yu B, Chen S, Chan DC, Hu J, Gao S., 2019
Mycobacterial dynamin-like protein IniA mediates membrane fission., Wang M, Guo X, Yang X, Zhang B, Ren J, Liu A, Ran Y, Yan B, Chen F, Guddat LW, Hu J, Li J, Rao Z., 2019
Reciprocal regulation between lunapark and atlastin facilitates ER three-way junction formation., Zhou X, He Y, Huang X, Guo Y, Li D, Hu J., 2019
Calumenin-1 Interacts with Climp63 to Cooperatively Determine the Luminal Width and Distribution of Endoplasmic Reticulum Sheets., Shen B, Zheng P, Qian N, Chen Q, Zhou X, Hu J, Chen J, Teng J., 2019
Visualizing Intracellular Organelle and Cytoskeletal Interactions at Nanoscale Resolution on Millisecond Timescales., Guo Y, Li D, Zhang S, Yang Y, Liu JJ, Wang X, Liu C, Milkie DE, Moore RP, Tulu US, Kiehart DP, Hu J, Lippincott-Schwartz J, Betzig E, Li D., 2018
LEM4 confers tamoxifen resistance to breast cancer cells by activating cyclin D-CDK4/6-Rb and ERα pathway., Gao A, Sun T, Ma G, Cao J, Hu Q, Chen L, Wang Y, Wang Q, Sun J, Wu R, Wu Q, Zhou J, Liu L, Hu J, Dong JT, Zhu Z., 2018
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling., Zheng P, Chen Q, Tian X, Qian N, Chai P, Liu B, Hu J, Blackstone C, Zhu D, Teng J, Chen J., 2018
Structural basis for GTP hydrolysis and conformational change of MFN1 in mediating membrane fusion., Yan L, Qi Y, Huang X, Yu C, Lan L, Guo X, Rao Z, Hu J, Lou Z., 2018
Transmembrane E3 ligase RNF183 mediates ER stress-induced apoptosis by degrading Bcl-xL., Wu Y, Li X, Jia J, Zhang Y, Li J, Zhu Z, Wang H, Tang J, Hu J., 2018
Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies., Qiu X, Lei Y, Yang P, Gao Q, Wang N, Cao L, Yuan S, Huang X, Deng Y, Ma W, Ding T, Zhang F, Wu X, Hu J, Liu SL, Qin C, Wang X, Xu Z, Rao Z., 2018
Sec61β facilitates the maintenance of endoplasmic reticulum homeostasis by associating microtubules., Zhu Y, Zhang G, Lin S, Shi J, Zhang H, Hu J., 2018
Sequences flanking the transmembrane segments facilitate mitochondrial localization and membrane fusion by mitofusin., Huang X, Zhou X, Hu X, Joshi AS, Guo X, Zhu Y, Chen Q, Prinz WA, Hu J., 2017
Quantitative proteomics reveal proteins enriched in tubular endoplasmic reticulum of Saccharomyces cerevisiae., Wang X, Li S, Wang H, Shui W, Hu J., 2017
Atlastin regulates store-operated calcium entry for nerve growth factor-induced neurite outgrowth., Li J, Yan B, Si H, Peng X, Zhang SL, Hu J., 2017
The Vici Syndrome Protein EPG5 Is a Rab7 Effector that Determines the Fusion Specificity of Autophagosomes with Late Endosomes/Lysosomes., Wang Z, Miao G, Xue X, Guo X, Yuan C, Wang Z, Zhang G, Chen Y, Feng D, Hu J, Zhang H., 2016
Fusion of the endoplasmic reticulum by membrane-bound GTPases., Hu J, Rapoport TA., 2016
Shaping the Endoplasmic Reticulum into a Social Network., Zhang H, Hu J., 2016
Identification of endoplasmic reticulum-shaping proteins in Plasmodium parasites., Sun S, Lv L, Yao Z, Bhanot P, Hu J, Wang Q., 2016
A Comprehensive Analysis of Plasmodium Circumsporozoite Protein Binding to Hepatocytes., Zhao J, Bhanot P, Hu J, Wang Q., 2016
A family of membrane-shaping proteins at ER subdomains regulates pre-peroxisomal vesicle biogenesis., Joshi AS, Huang X,
Area of Focus
Cyanobacteria | Ndh-1 | Structure | Function | Photosynthesis | Electron Transport | Biochemistry | Molecular Biology | Cell Biology | Genetics
