Professor | Pei Hao | Asia Growth Partners

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Name	Pei Hao
Contact Information	phao@ips.ac.cn
Language ability	Chinese, English
Province	Shanghai

Upload Avatar (500 x 500)

Name

Pei Hao

Contact Information

phao@ips.ac.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Areas of Focus	Bioinformatics Computational Biology Genomics Systems Biology Virus Molecular Evolution
Publications	Multi-valent mRNA vaccines against monkeypox enveloped or mature viron surface antigens demonstrate robust immune response and neutralizing activity., Zhang, Niubing, Cheng, Xiang, Zhu, Yilong, Mo, Ouyang, Yu, Huiqing, Zhu, Liqi, Zhang, Juan, Kuang, Linlin, Gao, Ying, Cao, Ruiyuan, Liang, Xiaozhen, Wang, Haikun, Li, Honglin, Li, Song, Zhong, Wu, Li, Xuan, Li, Xiao, Hao, Pei., 2023 DENA: training an authentic neural network model using Nanopore sequencing data of Arabidopsis transcripts for detection and quantification of N-6-methyladenosine on RNA., Qin, Hang, Ou, Liang, Gao, Jian, Chen, Longxian, Wang, JiaWei, Hao, Pei, Li, Xuan., 2022 Molecular dynamic simulation analysis of SARS-CoV-2 spike mutations and evaluation of ACE2 from pets and wild animals for infection risk., Chen, Ping, Wang, Jingfang, Xu, Xintian, Li, Yuping, Zhu, Yan, Li, Xuan, Li, Ming, Hao, Pei., 2022 Creating RNA Specific C-to-U Editase from APOBEC3A by Separation of Its Activities on DNA and RNA Substrates., Tang, Guiyue, Xie, Bingran, Hong, Xiangna, Qin, Hang, Wang, Jingfang, Huang, Hai, Hao, Pei, Li, Xuan., 2021 scSensitiveGeneDefine: sensitive gene detection in single-cell RNA sequencing data by Shannon entropy., Chen, Zechuan, Yang, Zeruo, Yuan, Xiaojun, Zhang, Xiaoming, Hao, Pei., 2021 Is SARS-CoV-2 originated from laboratory? A rebuttal to the claim of formation via laboratory recombination., Hao, Pei, Zhong, Wu, Song, Shiyang, Fan, Shiyong, Li, Xuan., 2020 Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission., Xu, Xintian, Chen, Ping, Wang, Jingfang, Feng, Jiannan, Zhou, Hui, Li, Xuan, Zhong, Wu, Hao, Pei., 2020 Two conserved epigenetic regulators prevent healthy ageing., Yuan, Jie, Chang, SiYuan, Yin, ShiGang, Liu, ZhiYang, Cheng, Xiu, Liu, XiJuan, Jiang, Qiang, Gao, Ge, Lin, DeYing, Kang, XinLei, Ye, ShiWei, Chen, Zheng, Yin, JiangAn, Hao, Pei, Jiang, Lubin, Cai, ShiQing., 2020 Molecular simulation of SARS-CoV-2 spike protein binding to pangolin ACE2 or human ACE2 natural variants reveals altered susceptibility to infection., Wang, Jingfang, Xu, Xintian, Zhou, Xinbo, Chen, Ping, Liang, Huiying, Li, Xuan, Zhong, Wu, Hao, Pei., 2020 Interfering with retrotransposition by two types of CRISPR effectors: Cas12a and Cas13a., Zhang, Niubing, Jing, Xinyun, Liu, Yuanhua, Chen, Minjie, Zhu, Xianfeng, Jiang, Jing, Wang, Hongbing, Li, Xuan, Hao, Pei., 2020 Microbiota in the apical root canal system of tooth with apical periodontitis., Qian, Wenhao, Ma, Ting, Ye, Mao, Li, Zhiyao, Liu, Yuanhua, Hao, Pei., 2019 乙肝病毒（HBV）感染对肝细胞癌（HCC）患者A-to-I RNA编辑的影响., 马婷, 黄海, 郝沛., 2019 Lupus-associated atypical memory B cells are mTORC1-hyperactivated and functionally dysregulated., Wu, Chunmei, Fu, Qiong, Guo, Qiang, Chen, Sheng, Goswami, Shyamal, Sun, Shuhui, Li, Teng, Cao, Xingjian, Chu, Fuying, Chen, Zechuan, Liu, Mei, Liu, Yuanhua, Fu, Ting, Hao, Pei, Hao, Yi, Shen, Nan, Bao, Chunde, Zhang, Xiaoming., 2019 Foxp1 is critical for the maintenance of regulatory T-cell homeostasis and suppressive function., Jiazi Ren, Lei Han, Jinyi Tang, Yuanhua Liu, Xiaoxue Deng, Qiuyue Liu, Pei Hao, Xiaoming Feng, Bin Li, Hui Hu, Haikun Wang., 2019 ZIKV infection induces robust Th1-like Tfh cell and long-term protective antibody responses in immunocompetent mice., Huabin Liang, Jinyi Tang, Zhihua Liu, Yuanhua Liu, Yuanyuan Huang, Yongfen Xu, Pei Hao, Zhinan Yin, Jin Zhong, Lilin Ye, Xia Jin, Haikun Wang., 2019 Iguratimod represses B cell terminal differentiation linked with the inhibition of PKC/EGR1 axis., Ye, Yan, Liu, Mei, Tang, Longhai, Du, Fang, Liu, Yuanhua, Hao, Pei, Fu, Qiong, Guo, Qiang, Yan, Qingran, Zhang, Xiaoming, Bao, Chunde., 2019 The nuclear receptor corepressor NCoR1 regulates hematopoiesis and leukemogenesis in vivo., Wan, Xiaoling, Liu, Lulu, Zhou, Peipei, Hui, Xinhui, He, Qiaomei, Yu, Fangfang, Zhang, Wei, Ding, Xiaodan, Yuan, Xiujie, Zhang, Na, Zhao, Yingxi, Zhu, Ruihong, Liu, Yuanhua, Hao, Pei, Auwerx, Johan, Song, Xianmin, Leng, Qibin, Zhang, Yan., 2019 Med23 serves as a gatekeeper of the myeloid potential of hematopoietic stem cells., Xufeng Chen, Jingyao Zhao, Chan Gu, Yu Cui, Yuling Dai, Guangrong Song, Haifeng Liu, Hao Shen, Yuanhua Liu, Yuya Wang, Huayue Xing, Xiaoyan Zhu, Pei Hao, Fan Guo, Xiaolong Liu., 2018 A survey on cellular RNA editing activity in response to Candida albicans infections., Huang, Yaowei, Cao, Yingying, Li, Jiarui, Liu, Yuanhua, Zhong, Wu, Li, Xuan, Chen, Chen, Hao, Pei., 2018 Modelling BioNano optical data and simulation study of genome map assembly., Chen, Ping, Jing, Xinyun, Ren, Jian, Cao, Han, Hao, Pei, Li, Xuan., 2018 A comprehensive study on cellular RNA editing activity in response to infections with different subtypes of influenza a viruses., Cao, Yingying, Cao, Ruiyuan, Huang, Yaowei, Zhou, Hongxia, Liu, Yuanhua, Li, Xuan, Zhong, Wu, Hao, Pei., 2018 Veratramine modulates AP-1-dependent gene transcription by directly binding to programmable DNA., Bai, Fang, Liu, Kangdong, Li, Huiliang, Wang, Jiawei, Zhu, Junsheng, Hao, Pei, Zhu, Lili, Zhang, Shoude, Shan, Lei, Ma, Weiya, Bode, Ann M, Zhang, Weidong, Li, Honglin, Dong, Zigang., 2018 Implementation of the CRISPR-Cas13a system in fission yeast and its repurposing for precise RNA editing., Jing, Xinyun, Xie, Bingran, Chen, Longxian, Zhang, Niubing, Jiang, Yiyi, Qin, Hang, Wang, Hongbing, Hao, Pei, Yang, Sheng, Li, Xuan., 2018 Elaboration of tetravalent antibody responses against dengue viruses using a subunit vaccine comprised of a single consensus dengue envelope sequence., Sun, Jin, Li, Min, Wang, Yinan, Hao, Pei, Jin, Xia., 2017 Comprehensive mapping of antigen specific T cell responses in hepatitis C virus infected patients with or without spontaneous viral clearance., Zhang, Chao, Hua, Rui, Cui, Yuanyuan, Wang, Shasha, Yan, Hongqing, Li, Dongmei, Zhang, Yonghong, Tu, Zhengkun, Hao, Pei, Chen, Xinyue, Zhong, Jin, Niu, Junqi, Jin, Xia., 2017 The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection., 郝沛., 2017 Pediatric Drug Nitazoxanide: A Potential Choice for Control of Zika., Cao, RuiYuan, Xu, Yongfen, Zhang, TianHong, Yang, JingJing, Yuan, Ye, Hao, Pei, Shi, Yi, Zhong, Jin, Zhong, Wu., 2017 Differential responses of innate immunity triggered by different subtypes of influenza a viruses in human and avian hosts., Cao, Yingying, Huang, Yaowei, Xu, Ke, Liu, Yuanhua, Li, Xuan, Xu, Ye, Zhong, Wu, Hao, Pei., 2017 Global transcriptome analysis reveals extensive gene remodeling, alternative splicing and differential transcription profiles in non-seed vascular plant Selaginella moellendorffii., Zhu, Yan, Chen, Longxian, Zhang, Chengjun, Hao, Pei, Jing, Xinyun, Li, Xuan., 2017 The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection., Yu, Yao, Zhou, Hongxia, Kong, Yimeng, Pan, Bohu, Chen, Longxian, Wang, Hongbing, Hao, Pei, Li, Xuan., 2016 The evolutionary landscape of intergenic trans-splicing events in insects., Kong, Yimeng, Zhou, Hongxia, Yu, Yao, Chen, Longxian, Hao, Pei, Li, Xuan., 2015 The Domain Landscape of Virus-Host Interactomes., Zheng, LuLu, Li, Chunyan, Ping, Jie, Zhou, Yanhong, Li, Yixue, Hao, Pei., 2014 Designing Peptide-Based HIV Vaccine for Chinese., Shu, Jiayi, Fan, Xiaojuan, Ping, Jie, Jin, Xia, Hao, Pei., 2014 Structure and Linkage Disequilibrium Analysis of Adamantane Resistant Mutations in Influenza Virus M2 Proton Channel., Yu, Yao, Li, Xuan, Hao, Pei, Wang, JingFang, Chou, KuoChen., 2014 Causal co-expression method with module analysis to screen drugs with specific target., Yu, Shuhao, Zheng, Lulu, Li, Yixue, Li, Chunyan, Ma, Chenchen, Yu, Yang, Li, Xuan, Hao, Pei., 2013 Expression Sensitivity Analysis of Human Disease Related Genes., Ma, LiangXiao, Wang, YaJun, Wang, JingFang, Li, Xuan, Hao, Pei., 2013 Molecular Dynamics Studies on the Conformational Transitions of Adenylate Kinase: A Computational Evidence for the Conformational Selection Mechanism., Ping, Jie, Hao, Pei, Li, YiXue, Wang, JingFang., 2013

Areas of Focus

Bioinformatics
Computational Biology
Genomics
Systems Biology
Virus Molecular Evolution

Publications

Multi-valent mRNA vaccines against monkeypox enveloped or mature viron surface antigens demonstrate robust immune response and neutralizing activity., Zhang, Niubing, Cheng, Xiang, Zhu, Yilong, Mo, Ouyang, Yu, Huiqing, Zhu, Liqi, Zhang, Juan, Kuang, Linlin, Gao, Ying, Cao, Ruiyuan, Liang, Xiaozhen, Wang, Haikun, Li, Honglin, Li, Song, Zhong, Wu, Li, Xuan, Li, Xiao, Hao, Pei., 2023
DENA: training an authentic neural network model using Nanopore sequencing data of Arabidopsis transcripts for detection and quantification of N-6-methyladenosine on RNA., Qin, Hang, Ou, Liang, Gao, Jian, Chen, Longxian, Wang, JiaWei, Hao, Pei, Li, Xuan., 2022
Molecular dynamic simulation analysis of SARS-CoV-2 spike mutations and evaluation of ACE2 from pets and wild animals for infection risk., Chen, Ping, Wang, Jingfang, Xu, Xintian, Li, Yuping, Zhu, Yan, Li, Xuan, Li, Ming, Hao, Pei., 2022
Creating RNA Specific C-to-U Editase from APOBEC3A by Separation of Its Activities on DNA and RNA Substrates., Tang, Guiyue, Xie, Bingran, Hong, Xiangna, Qin, Hang, Wang, Jingfang, Huang, Hai, Hao, Pei, Li, Xuan., 2021
scSensitiveGeneDefine: sensitive gene detection in single-cell RNA sequencing data by Shannon entropy., Chen, Zechuan, Yang, Zeruo, Yuan, Xiaojun, Zhang, Xiaoming, Hao, Pei., 2021
Is SARS-CoV-2 originated from laboratory? A rebuttal to the claim of formation via laboratory recombination., Hao, Pei, Zhong, Wu, Song, Shiyang, Fan, Shiyong, Li, Xuan., 2020
Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission., Xu, Xintian, Chen, Ping, Wang, Jingfang, Feng, Jiannan, Zhou, Hui, Li, Xuan, Zhong, Wu, Hao, Pei., 2020
Two conserved epigenetic regulators prevent healthy ageing., Yuan, Jie, Chang, SiYuan, Yin, ShiGang, Liu, ZhiYang, Cheng, Xiu, Liu, XiJuan, Jiang, Qiang, Gao, Ge, Lin, DeYing, Kang, XinLei, Ye, ShiWei, Chen, Zheng, Yin, JiangAn, Hao, Pei, Jiang, Lubin, Cai, ShiQing., 2020
Molecular simulation of SARS-CoV-2 spike protein binding to pangolin ACE2 or human ACE2 natural variants reveals altered susceptibility to infection., Wang, Jingfang, Xu, Xintian, Zhou, Xinbo, Chen, Ping, Liang, Huiying, Li, Xuan, Zhong, Wu, Hao, Pei., 2020
Interfering with retrotransposition by two types of CRISPR effectors: Cas12a and Cas13a., Zhang, Niubing, Jing, Xinyun, Liu, Yuanhua, Chen, Minjie, Zhu, Xianfeng, Jiang, Jing, Wang, Hongbing, Li, Xuan, Hao, Pei., 2020
Microbiota in the apical root canal system of tooth with apical periodontitis., Qian, Wenhao, Ma, Ting, Ye, Mao, Li, Zhiyao, Liu, Yuanhua, Hao, Pei., 2019
乙肝病毒（HBV）感染对肝细胞癌（HCC）患者A-to-I RNA编辑的影响., 马婷, 黄海, 郝沛., 2019
Lupus-associated atypical memory B cells are mTORC1-hyperactivated and functionally dysregulated., Wu, Chunmei, Fu, Qiong, Guo, Qiang, Chen, Sheng, Goswami, Shyamal, Sun, Shuhui, Li, Teng, Cao, Xingjian, Chu, Fuying, Chen, Zechuan, Liu, Mei, Liu, Yuanhua, Fu, Ting, Hao, Pei, Hao, Yi, Shen, Nan, Bao, Chunde, Zhang, Xiaoming., 2019
Foxp1 is critical for the maintenance of regulatory T-cell homeostasis and suppressive function., Jiazi Ren, Lei Han, Jinyi Tang, Yuanhua Liu, Xiaoxue Deng, Qiuyue Liu, Pei Hao, Xiaoming Feng, Bin Li, Hui Hu, Haikun Wang., 2019
ZIKV infection induces robust Th1-like Tfh cell and long-term protective antibody responses in immunocompetent mice., Huabin Liang, Jinyi Tang, Zhihua Liu, Yuanhua Liu, Yuanyuan Huang, Yongfen Xu, Pei Hao, Zhinan Yin, Jin Zhong, Lilin Ye, Xia Jin, Haikun Wang., 2019
Iguratimod represses B cell terminal differentiation linked with the inhibition of PKC/EGR1 axis., Ye, Yan, Liu, Mei, Tang, Longhai, Du, Fang, Liu, Yuanhua, Hao, Pei, Fu, Qiong, Guo, Qiang, Yan, Qingran, Zhang, Xiaoming, Bao, Chunde., 2019
The nuclear receptor corepressor NCoR1 regulates hematopoiesis and leukemogenesis in vivo., Wan, Xiaoling, Liu, Lulu, Zhou, Peipei, Hui, Xinhui, He, Qiaomei, Yu, Fangfang, Zhang, Wei, Ding, Xiaodan, Yuan, Xiujie, Zhang, Na, Zhao, Yingxi, Zhu, Ruihong, Liu, Yuanhua, Hao, Pei, Auwerx, Johan, Song, Xianmin, Leng, Qibin, Zhang, Yan., 2019
Med23 serves as a gatekeeper of the myeloid potential of hematopoietic stem cells., Xufeng Chen, Jingyao Zhao, Chan Gu, Yu Cui, Yuling Dai, Guangrong Song, Haifeng Liu, Hao Shen, Yuanhua Liu, Yuya Wang, Huayue Xing, Xiaoyan Zhu, Pei Hao, Fan Guo, Xiaolong Liu., 2018
A survey on cellular RNA editing activity in response to Candida albicans infections., Huang, Yaowei, Cao, Yingying, Li, Jiarui, Liu, Yuanhua, Zhong, Wu, Li, Xuan, Chen, Chen, Hao, Pei., 2018
Modelling BioNano optical data and simulation study of genome map assembly., Chen, Ping, Jing, Xinyun, Ren, Jian, Cao, Han, Hao, Pei, Li, Xuan., 2018
A comprehensive study on cellular RNA editing activity in response to infections with different subtypes of influenza a viruses., Cao, Yingying, Cao, Ruiyuan, Huang, Yaowei, Zhou, Hongxia, Liu, Yuanhua, Li, Xuan, Zhong, Wu, Hao, Pei., 2018
Veratramine modulates AP-1-dependent gene transcription by directly binding to programmable DNA., Bai, Fang, Liu, Kangdong, Li, Huiliang, Wang, Jiawei, Zhu, Junsheng, Hao, Pei, Zhu, Lili, Zhang, Shoude, Shan, Lei, Ma, Weiya, Bode, Ann M, Zhang, Weidong, Li, Honglin, Dong, Zigang., 2018
Implementation of the CRISPR-Cas13a system in fission yeast and its repurposing for precise RNA editing., Jing, Xinyun, Xie, Bingran, Chen, Longxian, Zhang, Niubing, Jiang, Yiyi, Qin, Hang, Wang, Hongbing, Hao, Pei, Yang, Sheng, Li, Xuan., 2018
Elaboration of tetravalent antibody responses against dengue viruses using a subunit vaccine comprised of a single consensus dengue envelope sequence., Sun, Jin, Li, Min, Wang, Yinan, Hao, Pei, Jin, Xia., 2017
Comprehensive mapping of antigen specific T cell responses in hepatitis C virus infected patients with or without spontaneous viral clearance., Zhang, Chao, Hua, Rui, Cui, Yuanyuan, Wang, Shasha, Yan, Hongqing, Li, Dongmei, Zhang, Yonghong, Tu, Zhengkun, Hao, Pei, Chen, Xinyue, Zhong, Jin, Niu, Junqi, Jin, Xia., 2017
The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection., 郝沛., 2017
Pediatric Drug Nitazoxanide: A Potential Choice for Control of Zika., Cao, RuiYuan, Xu, Yongfen, Zhang, TianHong, Yang, JingJing, Yuan, Ye, Hao, Pei, Shi, Yi, Zhong, Jin, Zhong, Wu., 2017
Differential responses of innate immunity triggered by different subtypes of influenza a viruses in human and avian hosts., Cao, Yingying, Huang, Yaowei, Xu, Ke, Liu, Yuanhua, Li, Xuan, Xu, Ye, Zhong, Wu, Hao, Pei., 2017
Global transcriptome analysis reveals extensive gene remodeling, alternative splicing and differential transcription profiles in non-seed vascular plant Selaginella moellendorffii., Zhu, Yan, Chen, Longxian, Zhang, Chengjun, Hao, Pei, Jing, Xinyun, Li, Xuan., 2017
The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection., Yu, Yao, Zhou, Hongxia, Kong, Yimeng, Pan, Bohu, Chen, Longxian, Wang, Hongbing, Hao, Pei, Li, Xuan., 2016
The evolutionary landscape of intergenic trans-splicing events in insects., Kong, Yimeng, Zhou, Hongxia, Yu, Yao, Chen, Longxian, Hao, Pei, Li, Xuan., 2015
The Domain Landscape of Virus-Host Interactomes., Zheng, LuLu, Li, Chunyan, Ping, Jie, Zhou, Yanhong, Li, Yixue, Hao, Pei., 2014
Designing Peptide-Based HIV Vaccine for Chinese., Shu, Jiayi, Fan, Xiaojuan, Ping, Jie, Jin, Xia, Hao, Pei., 2014
Structure and Linkage Disequilibrium Analysis of Adamantane Resistant Mutations in Influenza Virus M2 Proton Channel., Yu, Yao, Li, Xuan, Hao, Pei, Wang, JingFang, Chou, KuoChen., 2014
Causal co-expression method with module analysis to screen drugs with specific target., Yu, Shuhao, Zheng, Lulu, Li, Yixue, Li, Chunyan, Ma, Chenchen, Yu, Yang, Li, Xuan, Hao, Pei., 2013
Expression Sensitivity Analysis of Human Disease Related Genes., Ma, LiangXiao, Wang, YaJun, Wang, JingFang, Li, Xuan, Hao, Pei., 2013
Molecular Dynamics Studies on the Conformational Transitions of Adenylate Kinase: A Computational Evidence for the Conformational Selection Mechanism., Ping, Jie, Hao, Pei, Li, YiXue, Wang, JingFang., 2013

Bioinformatics Computational Biology Genomics Systems Biology Virus Molecular Evolution Mrna Vaccines Sars-Cov-2 Rna Editing Crispr Nanopore Sequencing

Qi Liu - Tongji University

Xiaoou Zhang - Tongji University

Guifen Liu - Tongji University

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