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Xuejun Jiang
Life Science
University of Chinese Academy of Sciences
Beijing
Language: English, Chinese
Autophagy
Egfr
Signaling Pathways
Fungal Metabolites
Cell Death
Cancer
Drug Development
Molecular Biology
Biochemistry
Microbiology
Areas of Focus
- Cell autophagy and epidermal growth factor receptor (EGFR) signaling pathways
- Fungal secondary metabolites and mammalian cell autophagy and death
Work Experience
- 2009-Present - Chinese Academy of Sciences, Institute of Microbiology - Researcher
- 2005-2006 - University of Colorado Health Sciences Center - Senior Visiting Scholar
- 2003-2009 - Chinese Academy of Sciences, Institute of Microbiology - Associate Researcher
- 2000-2002 - University of Colorado Health Sciences Center - Postdoctoral Fellow
- 1999-2000 - University of Utah School of Medicine - Postdoctoral Fellow
- 1998-1999 - Nagoya City University Medical School - Postdoctoral Fellow
- 1989-1992 - Zhangqiu People's Hospital, Shandong Province
- 1983-1988 - Jinan Steel Mingshui Refractory Materials Factory Hospital, Shandong Province
Academic Background & Achievements
- 1995-1998 Ph.D.: Peking University Health Science Center
- 1992-1995 Master's: Qingdao University Medical College
- 1980-1983 Diploma: Shandong Heze Medical School
Publications
- PARP and RIP 1 are required for autophagy induced by 11'-deoxyverticillin A, which precedes caspase-dependent apoptosis, Nan Zhang, Yali Chen, Ruixuan Jiang, Erwei Li, Xiuling Chen, Zhijun Xi, Yinglu Guo, Xingzhong Liu, Yuguang Zhou, Yongsheng Che and Xuejun Jiang, 2011
- Animal genes identification and mTOR signaling reactivation in Autophagy, Xuejun Jiang, 2010
- Mitochondrially localized EGFR is independent of its endocytosis and associates with cell viability, Yuan Yao, Gang Wang, Zhe Li, Bing Yan, Yinglu Guo, Xuejun Jiang, and Zhijun Xi, 2010
- Autophagy augmented by troglitazone is independent of EGFR transactivation and correlated with AMP-activated protein kinase signaling, Yan J, Yang H, Wang G, Sun L, Zhou Y, Guo Y, Xi Z, Jiang X, 2010
- Autophagy is involved in influenza A virus replication, Zhou Z, Jiang X, Liu D, Fang Z, Hu X, Yan J, Wang M, Gao GF, 2009
- Mitochondrially localized EGFR is subjected to autophagic regulation and implicated in cell survival, Yue X, Song W, Zhang W, Chen L, Xi Z, Xin Z, Jiang X, 2008
- Autophagy protects LNCaP cells under androgen deprivation conditions, Li M, Jiang X, Liu D, Na Y, Gao GF, Xi Z, 2008
- Epidermal Growth Factor Receptor Internalization through Clathrin-coated Pits requires Cbl RING finger and Proline-rich domains but not receptor Polyubiquitylation, Xuejun Jiang, Alexander Sorkin, 2003
- Coordinated Traffic of Grb2 and Ras during Epidermal Growth Factor Receptor Endocytosis Visualized in Living Cells, Xuejun Jiang, Alexander Sorkin, 2002
- Grb2 Regulates Internalization of EGF Receptors through Clathrin-coated Pits, Xuejun Jiang, Fangtian Huang, Andriy Marusyk, Alexander Sorkin, 2003
- Expression of osteopontin mRNA in normal and stone forming rat kidney, Jiang XJ, Feng T, Chang LS, Kong XT, Wang G, Zhang ZW, Guo YL, 1998
- Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain, F Huang, D Kirkpatrick, X Jiang, S Gygi, A Sorkin, 2006
- Tyrosine phosphorylation of the β2 subunit of clathrin adaptor complex AP-2 reveals the role of a di-leucine motif in the EGFR receptor trafficking, Fangtian Huang, Xuejun Jiang, Alexander Sorkin, 2003
- Troglitazone inhibits cell proliferation by attenuation of epidermal growth factor receptor signaling independent of peroxisome proliferator-activated receptor gamma, Li X, Yang X, Xu Y, Jiang X, Li X, Nan F, Tang H, 2009
