2006-09--2012-01 PhD: Shanghai Institute of Life Sciences, Chinese Academy of Sciences
2001-09--2006-07 Bachelor: Zhengzhou University
2023-10~Present - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Researcher
2017-03~2024-02 - Southern University of Science and Technology - Associate Professor, Researcher
2013-01~2017-03 - National Institutes of Health (NIH) - Postdoctoral Fellow
2012-01~2012-12 - Shanghai Institute of Life Sciences, Chinese Academy of Sciences - Assistant Researcher
2022: Outstanding Graduate Advisor, Southern University of Science and Technology
2022: Excellent Graduate Advisor, Southern University of Science and Technology
2019: Guangdong Pearl River Talent Plan Young Top Talent
Research
Development and integration of omics technologies and bioinformatics methods to enhance precision medicine Integration of multi-omics data to construct a holistic cell atlas and analyze cellular responses to external stimuli Utilization of single-cell technologies to analyze tumor microenvironment and tumor microevolution, and development of precision immunotherapy
Sirpα on tumor-associated myeloid cells restrains antitumor immunity in colorectal cancer independent of its interaction with CD47, Wenfei Jin, 2024
Single cell analyses of cancer cells identified two regulatorily and functionally distinct categories in differentially expressed genes among tumor subclones, Wenfei Jin, 2024
Proline uptake promotes activation of lymphoid tissue inducer cells to maintain gut homeostasis, Wenfei Jin, 2023
A fast and globally optimal solution for RNA-seq quantification, Wenfei Jin, 2023
ISSAAC-seq enables sensitive and flexible multimodal profiling of chromatin accessibility and gene expression in single cells, Wenfei Jin, 2022
Reinvestigation of Classic T Cell Subsets and Identification of Novel Cell Subpopulations by Single-Cell RNA Sequencing, Wenfei Jin, 2022
Single-Cell RNA Sequencing Unravels Upregulation of Immune Cell Crosstalk in Relapsed Pediatric Ependymoma, Wenfei Jin, 2022
Dissecting Complex Traits Using Omics Data: A Review on the Linear Mixed Models and Their Application in GWAS, Wenfei Jin, 2022
Comprehensive mapping of alternative polyadenylation site usage and its dynamics at single-cell resolution, Wenfei Jin, 2022
A topology-preserving dimensionality reduction method for single-cell RNA-seq data using graph autoencoder, Wenfei Jin, 2021
Integrated decoding hematopoiesis and leukemogenesis using single-cell sequencing and its medical implication, Wenfei Jin, 2021
Kssd: sequence dimensionality reduction by k-mer substring space sampling enables real-time large-scale datasets analysis, Wenfei Jin, 2021
Cross-Tissue Characterization of Heterogeneities of Mesenchymal Stem Cells and Their Differentiation Potentials, Wenfei Jin, 2021
A plate-based single-cell ATAC-seq workflow for fast and robust profiling of chromatin accessibility, Wenfei Jin, 2021
A Comprehensive Characterization of Monoallelic Expression During Hematopoiesis and Leukemogenesis via Single-Cell RNA-Sequencing, Wenfei Jin, 2021
The Tyrosine Kinase-Driven Networks of Novel Long Non-coding RNAs and Their Molecular Targets in Myeloproliferative Neoplasms, Wenfei Jin, 2021
Focal adhesion protein Kindlin-2 regulates bone homeostasis in mice, Wenfei Jin, 2020
H4K20me3 methyltransferase SUV420H2 shapes the chromatin landscape of pluripotent embryonic stem cells, Wenfei Jin, 2020
Diploid genome architecture revealed by multi-omic data of hybrid mice, Wenfei Jin, 2020
Kindlin-2 regulates skeletal homeostasis by modulating PTH1R in mice, Wenfei Jin, 2020
Single-Cell Transcriptome Analysis Reveals Six Subpopulations Reflecting Distinct Cellular Fates in Senescent Mouse Embryonic Fibroblasts, Wenfei Jin, 2020
Inhibition of Glycolysis in Pathogenic T(H)17 Cells through Targeting a miR-21-Peli1-c-Rel Pathway Prevents Autoimmunity, Wenfei Jin, 2020
Exploring the changing landscape of cell-to-cell variation after CTCF knockdown via single cell RNA-seq, Wenfei Jin, 2019
Principles of nucleosome organization revealed by single-cell micrococcal nuclease sequencing (vol 562, pg 281, 2018), Wenfei Jin, 2018
Trac-looping measures genome structure and chromatin accessibility, Wenfei Jin, 2018
Principles of nucleosome organization revealed by single-cell micrococcal nuclease sequencing, Wenfei Jin, 2018
Transformation of Accessible Chromatin and 3D Nucleome Underlies Lineage Commitment of Early T Cells, Wenfei Jin, 2018
CTCF-Mediated Enhancer-Promoter Interaction Is a Critical Regulator of Cell-to-Cell Variation of Gene Expression, Wenfei Jin, 2017
Genome-wide identification of histone H2A and histone variant H2A.Z-interacting proteins by bPPI-seq, Wenfei Jin, 2017
Genome-wide incorporation dynamics reveal distinct categories of turnover for the histone variant H3.3 (vol 14, R121, 2013), Wenfei Jin, 2016
Evaluating information content of SNPs for sample-tagging in re-sequencing projects, Wenfei Jin, 2015
Copy number variations and genetic admixtures in three *** ethnic minority groups, Wenfei Jin, 2015
Genome-wide detection of DNase I hypersensitive sites in single cells and FFPE tissue samples, Wenfei Jin, 2015
Y Chromosomes of 40% Chinese Descend from Three Neolithic Super-Grandfathers, Wenfei Jin, 2014
Distribution of ancestral chromosomal segments in admixed genomes and its implications for inferring population history and admixture mapping, Wenfei Jin, 2014
A panel of ancestry informative markers to estimate and correct potential effects of population stratification in Han Chinese, Wenfei Jin, 2014
Association of Two Variants in SMAD7 with the Risk of Congenital Heart Disease in the Han Chinese Population, Wenfei Jin, 2013
Genome-wide incorporation dynamics reveal distinct categories of turnover for the histone variant H3.3, Wenfei Jin, 2013
A systematic characterization of genes underlying both complex and Mendelian diseases, Wenfei Jin, 2012
Genome-wide detection of natural selection in African Americans pre- and post-admixture, Wenfei Jin, 2012
Exploring Population Admixture Dynamics via Empirical and Simulated Genome-wide Distribution of Ancestral Chromosomal Segments, Wenfei Jin, 2012
A Map of Copy Number Variations in Chinese Populations, Wenfei Jin, 2011
A Genome-Wide Search for Signals of High-Altitude Adaptation in Tibetans, Wenfei Jin, 2011
Area of Focus
Ai | Omics | Precision Medicine | Bioinformatics | Data Analysis | Genomics | Crispr | Machine Learning | Drug Design | Single-Cell Analysis
