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Lanlan Liu
Life Science
University of Chinese Academy of Sciences
Guangdong
Language: Chinese, English
Micro/Nano
Biomimetic
Drug Delivery
Gene Therapy
Anti-Tumor
Photoimmunotherapy
Cancer
Nanoparticles
Biomedical
Therapeutics
Areas of Focus
- Micro/Nano Biomimetic Drug Delivery
- Gene Therapy
- Anti-tumor Photoimmunotherapy
Work Experience
- 2020-01 to Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher
- 2017-01 to 2019-12 - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Assistant Researcher
- 2012-07 to 2016-12 - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Research Assistant
Academic Background & Achievements
- 2017-09 to 2020-06 PhD: University of Chinese Academy of Sciences
- Outstanding Graduate: University of Chinese Academy of Sciences
- Outstanding Graduate: Beijing Municipal Universities
- CAS President's Excellence Award
- National Scholarship for Doctoral Students
- Zhu Li Yuehua Scholarship
Publications
- Reconstructing Tumor Microenvironment Using Photoresponsive Cyanobacteria to Reversal Chemoresistance for Robust Chemotherapy, Lanlan Liu, 2023
- A Dual-Biomineralized Yeast Micro-/Nanorobot with Self-Driving Penetration for Gastritis Therapy and Motility Recovery, Lanlan Liu, 2023
- Biomimetic Nanosonosensitizers Combined with Noninvasive Ultrasound Actuation to Reverse Drug Resistance and Sonodynamic-Enhanced Chemotherapy against Orthotopic Glioblastoma, Lanlan Liu, 2022
- Biomimetic Active Materials Guided Immunogenic Cell Death for Enhanced Cancer Immunotherapy, Lanlan Liu, 2022
- Cell/Bacteria-Based Bioactive Materials for Cancer Immune Modulation and Precision Therapy, Lanlan Liu, 2021
- Click CAR-T cell engineering for robustly boosting cell immunotherapy in blood and subcutaneous xenograft tumor, Lanlan Liu, 2021
- Noninvasively immunogenic sonodynamic therapy with manganese protoporphyrin liposomes against triple-negative breast cancer, Lanlan Liu, 2021
- In situ poly I:C released from living cell drug nanocarriers for macrophage-mediated antitumor immunotherapy, Lanlan Liu, 2021
- In Situ Photocatalyzed Oxygen Generation with Photosynthetic Bacteria to Enable Robust Immunogenic Photodynamic Therapy in Triple-Negative Breast Cancer, Lanlan Liu, 2020
- Up-regulation of miR-27a promotes monocyte-mediated inflammatory responses in Kawasaki disease by inhibiting function of B10 cells, Lanlan Liu, 2020
- Tumor-targeted nanoplatform for in situ oxygenation-boosted immunogenic phototherapy of colorectal cancer, Lanlan Liu, 2020
- Bioorthogonal Metabolic Labeling Utilizing Protein Biosynthesis for Dynamic Visualization of Nonenveloped Enterovirus 71 Infection, Lanlan Liu, 2020
- Synergistic effect of all-trans-retinal and triptolide encapsulated in an inflammation-targeted nanoparticle on collagen-induced arthritis in mice, Lanlan Liu, 2020
- Smart gold nanocages for mild heat-triggered drug release and breaking chemoresistance, Lanlan Liu, 2020
- Bio-Orthogonal T Cell Targeting Strategy for Robustly Enhancing Cytotoxicity against Tumor Cells, Lanlan Liu, 2019
- Glycometabolic Bioorthogonal Chemistry-Guided Viral Transduction for Robust Human T Cell Engineering, Lanlan Liu, 2019
- Bioinspired Hybrid Protein Oxygen Nanocarrier Amplified Photodynamic Therapy for Eliciting Anti-tumor Immunity and Abscopal Effect, Lanlan Liu, 2018
- Oxygen-boosted immunogenic photodynamic therapy with gold nanocages@manganese dioxide to inhibit tumor growth and metastases, Lanlan Liu, 2018
- Ros-inducing micelles sensitize tumor-associated macrophages to tlr3 stimulation for potent immunotherapy, Lanlan Liu, 2018
- Dissecting complicated viral spreading of enterovirus 71 using in situ bioorthogonal fluorescent labeling, Lanlan Liu, 2018
- Tumor-targeted hybrid protein oxygen carrier to simultaneously enhance hypoxia-dampened chemotherapy and photodynamic therapy at a single dose, Lanlan Liu, 2018
- Cancer Cell Membrane-Biomimetic Oxygen Nanocarrier for Breaking Hypoxia-Induced Chemoresistance, Lanlan Liu, 2017
- Tumor associated macrophage-targeted microRNA delivery with dual-responsive polypeptide nanovectors for anti-cancer therapy, Lanlan Liu, 2017
- In Situ Bioorthogonal Metabolic Labeling for Fluorescence Imaging of Virus Infection In Vivo., Lanlan Liu, 2017
- Cancer Cell Membrane-Biomimetic Nanoparticles for Homologous-Targeting Dual-Modal Imaging and Photothermal Therapy, Lanlan Liu, 2016
- Retinal-conjugated pH-sensitive micelles induce tumor senescence for boosting breast cancer chemotherapy, Lanlan Liu, 2016
- Self-adjuvanted nanovaccine for cancer immunotherapy: Role of lysosomal rupture-induced ROS in MHC class I antigen presentation, Lanlan Liu, 2016
- Synergistic Therapy of Doxorubicin and miR-129-5p with Self-Cross-Linked Bioreducible Polypeptide Nanoparticles Reverses Multidrug Resistance in Cancer Cells, Lanlan Liu, 2016
- Integrated Nanovaccine with MicroRNA-148a Inhibition Reprograms Tumor-Associated Dendritic Cells by Modulating miR-148a/DNMT1/SOCS1 Axis, Lanlan Liu, 2016
- Sialic Acid-Targeted Nanovectors with Phenylboronic Acid-Grafted Polyethylenimine Robustly Enhance siRNA-Based Cancer Therapy, Lanlan Liu, 2016
- Lymphatic-targeted cationic liposomes: A robust vaccine adjuvant for promoting long-term immunological memory, Lanlan Liu, 2015
- Co-delivery of poly I:C and STAT3 siRNA by nanovaccines effectively overcomes tumor-associated dendritic cell dysfunction and elicits anti-tumor immune response, Lanlan Liu, 2015
- Nanovaccine loaded with poly I:C and STAT3 siRNA robustly elicits anti-tumor immune responses through modulating tumor-associated dendritic cells invivo, Lanlan Liu, 2015
- Autophagy mediates avian influenza H5N1 pseudotyped particle-induced lung inflammation through NF-kappa B and p38 MAPK signaling pathways, Lanlan Liu, 2014
- Noninvasive Visualization of Respiratory Viral Infection Using Bioorthogonal Conjugated Near-Infrared-Emitting Quantum Dots, Lanlan Liu, 2014
- Lymphatic-targeted cationic liposomes: A robust vaccine adjuvant for promoting long-term immunological memory, Lanlan Liu, 2014
- Functionalized quantum dots induce proinflammatory responses in vitro: the role of terminal functional group-associated endocytic pathways, Lanlan Liu, 2013
- Inhibition of Oxidative Stress-Elicited AKT Activation Facilitates PPAR gamma Agonist-Mediated Inhibition of Stem Cell Character and Tumor Growth of Liver Cancer Cells, Lanlan Liu, 2013
- Bioreducible alginate-poly(ethylenimine) nanogels as an antigen-delivery system robustly enhance vaccine-elicited humoral and cellular immune responses, Lanlan Liu, 2013
Awards
- Outstanding Employee (2021): Research Institute
- Shenzhen Natural Science Award, First Prize (2020): Municipal Level
- Outstanding Graduate (2020): University of Chinese Academy of Sciences
- Outstanding Graduate (2020): Beijing Municipal Universities
- Outstanding Employee (2020): Research Institute
- CAS President's Excellence Award (2019): Institute Level
- National Scholarship for Doctoral Students (2019): National Level
- Zhu Li Yuehua Scholarship (2019): Research Institute
- Outstanding Employee (2018): Research Institute
- Outstanding Employee (2017): Research Institute
- Outstanding Employee (2016): Research Institute
