Areas of Focus
- Cell Biology: Lipid Droplet Biology, Lipid Storage and Metabolism, Mechanisms of Metabolic Diseases
Work Experience
- 2009-09 to Present - Nanjing University - Part-time Professor
- 2008-07 to Present - Institute of Biophysics, Chinese Academy of Sciences - Research Group Leader
- 2002-09 to Present - Guizhou University - Part-time Professor
- 1999-07 to 2008-07 - University of Texas Southwestern Medical Center - Research Assistant Professor
- 1997-07 to 1999-07 - University of Texas Southwestern Medical Center - Instructor
- 1994-09 to 1997-07 - University of Texas Southwestern Medical Center - Postdoctoral Fellow
Academic Background & Achievements
- 1987-09 to 1994-07 PhD: Clarkson University, NY, USA
- 1982-09 to 1985-07 Master's Degree: China National Light Industry Institute
- 1978-09 to 1982-07 Bachelor's Degree: Guizhou University
Publications
- HDAC6 Suppresses Age-Dependent Ectopic Fat Accumulation by Maintaining the Proteostasis of PLIN2 in Drosophila, 6th Author, 2017
- Omic studies reveal the pathogenic lipid droplet proteins in non-alcoholic fatty liver disease, Corresponding Author, 2017
- Bacterial lipid droplets bind to DNA via an intermediary protein that enhances survival under stress, Corresponding Author, 2017
- Lipid droplet proteins and metabolic diseases, Corresponding Author, 2017
- The lipid droplet: A conserved cellular organelle, Corresponding Author, 2017
- Comparative Proteomic Study of Fatty Acid-treated Myoblasts Reveals Role of Cox-2 in Palmitate-induced Insulin Resistance, Corresponding Author, 2016
- Construction of Nano-Droplet/Adiposome and Artificial Lipid Droplets, Corresponding Author, 2016
- Comparative proteomics reveals abnormal binding of ATGL and dysferlin on lipid droplets from pressure overload-induced dysfunctional rat hearts, Corresponding Author, 2016
- Morphologically and Functionally Distinct Lipid Droplet Subpopulations, Corresponding Author, 2016
- Proteomic analysis of murine testes lipid droplets, Corresponding Author, 2016
- Lipid droplet remodeling and interaction with mitochondria in mouse brown adipose tissue during cold treatment, Corresponding Author, 2015
- Identification of lipid droplet structure-like/resident proteins in Caenorhabditis elegans, Corresponding Author, 2015
- Proteomic analysis of murine testes lipid droplets, Corresponding Author, 2015
- Integrated omics study delineates the dynamics of lipid droplets in Rhodococcus opacus PD63, Corresponding Author, 2014
- Comparative proteomic study reveals 17β-HSD13 as a pathogenic protein in non-alcoholic fatty liver disease, Corresponding Author, 2014
- Isolating lipid droplets from multiple specie, Corresponding Author, 2013
- Proteomic Study and Marker Protein Identification of Caenorhabditis elegans Lipid Droplets, Corresponding Author, 2012
- The proteomics of lipid droplets: structure, dynamics, and functions of the organelle conserved from bacteria to humans, Corresponding Author, 2012
- Oleate blocks palmitate-induced abnormal lipid distribution, endoplasmic reticulum expansion and stress, and insulin resistance in skeletal muscle, Corresponding Author, 2011
- Identification of the major functional proteins of prokaryotic lipid droplets, Corresponding Author, 2011
- Proteome of Skeletal Muscle Lipid Droplet Reveals Association with Mitochondria and Apolipoprotein A-I, Corresponding Author, 2011
- Reducing COD and BOD, as well as Producing Triacylglycerol by LDS5 Grown in CTMP Effluent, Corresponding Author, 2011
- Alteration of microRNA expression correlates to fatty acid-mediated insulin resistance in mouse myoblasts, Corresponding Author, 2011
- Palmitic acid acutely stimulates glucose uptake via activation of Akt and ERK1/2 in skeletal muscle cells, Corresponding Author, 2011
- A role for lipid droplets in inter-membrane, Corresponding Author, 2009
- Dynamic activity of lipid droplets: protein phosphorylation and GTP-mediated protein translocation, Corresponding Author, 2007
- Lipidomics reveals that adiposomes store ether lipids and mediate phospholipids traffic, Corresponding Author, 2007
- Proteomics reveals CHO cell lipid droplets are metabolic organelles involved membrane traffic, 1st Author, 2004
- Multiple functions of caveolin-1, 1st Author, 2002
- Caveolin-1, an integral membrane protein of caveolae, is secreted as a lipoprotein by serous exocrine cells, 1st Author, 1999
- Platelet-derived growth factor activates mitogen-activated protein kinase in isolated caveolae, 1st Author, 1997
- Localization of PDGF-stimulated phosphorylation cascade to caveolae, 1st Author, 1996
- The IL-1β-mediated ceramide signaling in human fibroblasts originates in caveolae, 1st Author, 1995