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Zhihua Liu
Life Science
University of Chinese Academy of Sciences
Beijing
Language: Chinese, English
Intestinal Mucosa
Gut Microbiota
Molecular Mechanisms
Physiological Significance
Germ-Free Animals
Gnotobiotic Animals
Intestinal Barrier
Cellular Activities
Homeostasis
Regulation
Areas of Focus
- Molecular mechanisms and physiological significance of interactions between specialized intestinal mucosal cells and gut microbiota
Work Experience
- 2006-2011 - National Institutes of Health - Postdoctoral Researcher
- 2012-Present - Institute of Biophysics, Chinese Academy of Sciences - Researcher
Academic Background & Achievements
- 1995-1999 Bachelor: Peking University
- 1999-2005 PhD: Harvard University
- Achievement: National 'Youth' Award
- Achievement: CAS-Novo Nordisk 'Great Wall Professor'
Publications
- LRRK2 enhances Nod1/2-mediated inflammatory cytokine production by promoting Rip2 phosphorylation, Zhihua Liu, 2017
- Rip2 Is Required for Nod2-Mediated Lysozyme Sorting in Paneth Cells, Zhihua Liu, 2017
- Commensal bacteria direct selective cargo sorting to promote symbiosis, Zhihua Liu, 2015
- Leucine-rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER-Golgi export, Zhihua Liu, 2014
- The role of LRRK2 in inflammatory bowel disease, Zhihua Liu, 2012
- LRRK2 is a regulator of NFAT that modulates the severity of inflammatory bowel disease, Zhihua Liu, 2011
- Membrane-associated farnesylated UCH-L1 promotes alpha-synuclein neurotoxicity and is a therapeutic target for Parkinsons disease, Zhihua Liu, 2009
- Reactive oxygen species regulate autophagy through redox-sensitive proteases, Zhihua Liu, 2006
- The UCH-L1 gene encodes two opposing enzymatic activities that affect alpha-synuclein degradation and Parkinsons disease susceptibility, Zhihua Liu, 2002
- Correlation between transcritptome and interactome mapping data from Saccharomyces cerevisiae, Zhihua Liu, 2001
Awards
- 2012: National 'Youth' Award
- 2012: CAS-Novo Nordisk 'Great Wall Professor'
- 2015: National 'Outstanding Youth Fund'
