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Zhen Liu
Life Science
University of Chinese Academy of Sciences
Shanghai
Language: Chinese, English
Development
Embryo
Reproduction
Physiology
Cell
Reprogramming
Neuroendocrinology
Hormones
Genetics
Stem Cells
Areas of Focus
- Embryonic Development
- Reproductive Physiology
- Cell Reprogramming
- Neuroendocrinology of Reproduction
Work Experience
- 2018-09~Present - Chinese Academy of Sciences Center for Excellence in Brain Science and Intelligence Technology - Researcher
- 2017-07~2018-08 - Institute of Neuroscience, Chinese Academy of Sciences - Postdoctoral Fellow
- 2013-07~2014-08 - Institute of Neuroscience, Chinese Academy of Sciences - Research Intern
Academic Background & Achievements
- 2014-09--2017-06 PhD: University of Chinese Academy of Sciences
- 2010-09--2013-06 Master's: University of Chinese Academy of Sciences
- 2006-09--2010-06 Bachelor's: Shandong Normal University
Publications
- Base-edited cynomolgus monkeys mimic core symptoms of STXBP1 encephalopathy, Corresponding Author, 2022
- Mitochondrial replacement in macaque monkey offspring by first polar body transfer, Corresponding Author, 2021
- Efficient and risk-reduced genome editing using double nicks enhanced by bacterial recombination factors in multiple species, Third Author, 2020
- Single-cell CAS-seq reveals a class of short PIWI-interacting RNAs in human oocytes, Fifth Author, 2019
- Serum anti-Mullerian hormone predicts ovarian response in (Macaca fascicularis) monkeys, Seventh Author, 2018
- Cloning of Macaque Monkeys by Somatic Cell Nuclear Transfer, First Author, 2018
- Efficient generation of mouse models of human diseases via ABE- and BE-mediated base editing, First Author, 2018
- Generation of knock-in cynomolgus monkey via CRISPR/Cas9 editing, Second Author, 2018
- Homology-mediated end joining-based targeted integration using crispr/cas9, Fourth Author, 2017
- One-step generation of complete gene knockout mice and monkeys by crispr/cas9-mediated gene editing with multiple sgrnas, Seventh Author, 2017
- Generation of macaques with sperm derived from juvenile monkey testicular xenografts, First Author, 2016
- Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2, First Author, 2016
- Generation of haploid embryonic stem cells from Macaca fascicularis monkey parthenotes, Second Author, 2013
Awards
- Shanghai Science and Technology Award (2023): First Prize, Provincial Level
- Outstanding Young Researcher in Stem Cells (2023): Other
- China Youth May Fourth Medal (2021): Ministerial Level
- Shanghai Youth May Fourth Medal (2021): Provincial Level
- Advanced Worker of the Chinese Academy of Sciences (2019): Institute Level
- Ho Leung Ho Lee Foundation Science and Technology Innovation Award (2019): Special
- CAS Innovation Cross Team (2018): Academy Level
- CAS President's Special Award (2016): Academy Level
