2003-09 to 2009-06 PhD: Peking University, School of Physics and Center for Theoretical Biology
1999-09 to 2003-07 Bachelor's: Wuhan University, School of Physics
2013-03 to 2019-06 - Chinese Academy of Sciences, Institute of Microbiology - Researcher
2011-09 to 2013-01 - Massachusetts Institute of Technology (MIT) - Postdoctoral Researcher
2009-08 to 2011-08 - University of California, San Francisco (UCSF) - Postdoctoral Researcher
Research
Design of Artificial Life Forms Gene Circuit Design and Application in Mammalian Cells Pathogen Vaccine Development Safety and Controllability of Artificial Life Forms Design of Artificial Phages Targeting Intracellular Mycobacterium Tuberculosis in Macrophages
Precise programming of multigene expression stoichiometry in mammalian cells by a modular and programmable transcriptional system., Chenrui Qin, Yanhui Xiang, Jie Liu, Ruilin Zhang, Ziming Liu, Tingting Li, Zhi Sun, Xiaoyi Ouyang, Yeqing Zong, Haoqian M. Zhang, Qi Ouyang, Long Qian, Chunbo Lou., 2023
The Topological Characteristics of Biological Ratio-Sensing Networks., Chen, Xinmao, Wang, Tianze, Guan, Ying, Ouyang, Qi, Lou, Chunbo, Qian, Long., 2023
Improving cooperativity of transcription activators by oligomerization domains in mammalian cells., Xinmao Chen, Ziming Liu, Chunbo Lou, Ying Guan, Qi Ouyang, Yanhui Xiang., 2022
Multiplexed Promoter Engineering for Improving Thaxtomin A Production in Heterologous Streptomyces Hosts., Xuejin Zhao, Yeqing Zong, Weijia Wei, Chunbo Lou, Pasquale Stano, Jun Ni., 2022
Mitigating Host Burden of Genetic Circuits by Engineering Autonegatively Regulated Parts and Improving Functional Prediction., Guan, Ying, Chen, Xinmao, Shao, Bin, Ji, Xiangyu, Xiang, Yanhui, Jiang, Guoqiang, Xu, Lina, Lin, Zhanglin, Ouyang, Qi, Lou, Chunbo., 2022
Engineered DNase-inactive Cpf1 variants to improve targeting scope for base editing in E. coli., Chen, Zehua, Sun, Jinyuan, Guan, Ying, Li, Ming, Lou, Chunbo, Wu, Bian., 2021
CRISPR-Based Genetic Switches and Other Complex Circuits: Research and Application., Pei Du, Chunbo Lou, Xuejin Zhao, Qihui Wang, Xiangyu Ji, Weijia Wei, Llus Ribas de Pouplana., 2021
De novo design of an intercellular signaling toolbox for multi-channel cell-cell communication and biological computation., Pei Du, Huiwei Zhao, Haoqian Zhang, Ruisha Wang, Jianyi Huang, Ye Tian, Xudong Luo, Xunxun Luo, Min Wang, Yanhui Xiang, Long Qian, Yihua Chen, Yong Tao, Chunbo Lou., 2020
CRISPRi/dCpf1-mediated dynamic metabolic switch to enhance butenoic acid production in Escherichia coli., Ji, Xiangyu, Zhao, Huiwei, Zhu, Hua, Zhu, Kun, Tang, ShuangYan, Lou, Chunbo., 2020
A tight cold-inducible switch built by coupling thermosensitive transcriptional and proteolytic regulatory parts., Zheng, Yang, Meng, Fankang, Zhu, Zihui, Wei, Weijia, Sun, Zhi, Chen, Jinchun, Yu, Bo, Lou, Chunbo, Chen, GuoQiang.
Systematically investigating the key features of the DNase deactivated Cpf1 for tunable transcription regulation in prokaryotic cells., Miao, Chensi, Zhao, Huiwei, Qian, Long, Lou, Chunbo., 2019
Engineering the Ultrasensitive Transcription Factors by Fusing a Modular Oligomerization Domain., Hou, Junran, Zeng, Weiqian, Zong, Yeqing, Chen, Zehua, Miao, Chensi, Wang, Baojun, Lou, Chunbo., 2018
人工遗传改造生命体的防逃逸技术研究进展., 孟凡康, 娄春波., 2018
Paired Design of dCas9 as a Systematic Platform for the Detection of Featured Nucleic Acid Sequences in Pathogenic Strains., Zhang, Yihao, Qian, Long, Wei, Weijia, Wang, Yu, Wang, Beining, Lin, Pingping, Liu, Wenchao, Xu, Luze, Li, Xiang, Liu, Dongming, Cheng, Sida, Li, Jiaofeng, Ye, Yixuan, Li, Hang, Zhang, Xiaohan, Dong, Yiming, Zhao, Xuejin, Liu, Cuihua, Zhang, Haoqian M, Ouyang, Qi, Lou, Chunbo., 2017
Construction of an easy-to-use CRISPR-Cas9 system by patching a newly designed EXIT circuit., Tang, Qiang, Lou, Chunbo, Liu, ShuangJiang., 2017
人工基因元件的生理学研究进展., 季翔宇, 赵会伟, 娄春波., 2017
Insulated transcriptional elements enable precise design of genetic circuits., Yeqing Zong, Haoqian M Zhang, Cheng Lyu, Xiangyu Ji, Junran Hou, Xian Guo, Qi Ouyang, Chunbo Lou., 2017
Semirational Approach for Ultrahigh Poly(3-hydroxybutyrate) Accumulation in Escherichia coli by Combining One-Step Library Construction and High-Throughput Screening., Li, Teng, Ye, Jianwen, Shen, Rui, Zong, Yeqing, Zhao, Xuejin, Lou, Chunbo, Chen, GuoQiang., 2016
Intermediate-sensor assisted push-pull strategy and its application in heterologous deoxyviolacein production in Escherichia coli., Fang, Mingyue, Wang, Tianmin, Zhang, Chong, Bai, Jili, Zheng, Xiang, Zhao, Xuejin, Lou, Chunbo, Xing, XinHui., 2016
Exploiting a precise design of universal synthetic modular regulatory elements to unlock the microbial natural products in Streptomyces., Bai, Chaoxian, Zhang, Yang, Zhao, Xuejin, Hu, Yiling, Xiang, Sihai, Miao, Jin, Lou, Chunbo, Zhang, Lixin.
Cas9-Assisted Targeting of CHromosome segments CATCH enables one-step targeted cloning of large gene clusters., Jiang, Wenjun, Zhao, Xuejin, Gabrieli, Tslil, Lou, Chunbo, Ebenstein, Yuval, Zhu, Ting F., 2015
Ribozyme-based insulator parts buffer synthetic circuits from genetic context., Lou, Chunbo, Stanton, Brynne, Chen, YingJa, Munsky, Brian, Voigt, Christopher A., 2012
Genetic programs constructed from layered logic gates in single cells., Moon, Tae Seok, Lou, Chunbo, Tamsir, Alvin, Stanton, Brynne C, Voigt, Christopher A.
A molecular model for persister in E. coli., Lou, Chunbo, Li, Zhengyan, Qi Ouyang., 2008
A quantitative study of lambda-phage SWITCH and its components., Lou, Chunbo, Yang, Xiaojing, Liu, Xili, He, Bin, Qi Ouyang., 2007
Paired dCas9 design as a nucleic acid detection platform for pathogenic strains., Yihao Zhang, Yu Wang, Luze Xu, Chunbo Lou, Qi Ouyang, Long Qian., 2021
